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Recent work in machine learning shows that deep neural networks can be used to solve a wide variety of inverse problems arising in computational imaging. We explore the central prevailing themes of this emerging area and present a taxonomy…

Image and Video Processing · Electrical Eng. & Systems 2020-05-14 Gregory Ongie , Ajil Jalal , Christopher A. Metzler , Richard G. Baraniuk , Alexandros G. Dimakis , Rebecca Willett

Operator learning offers a robust framework for approximating mappings between infinite-dimensional function spaces. It has also become a powerful tool for solving inverse problems in the computational sciences. This chapter surveys…

Numerical Analysis · Mathematics 2025-12-08 Nicholas H. Nelsen , Yunan Yang

Nonlinear parametric inverse problems appear in several prominent applications; one such application is Diffuse Optical Tomography (DOT) in medical image reconstruction. Such inverse problems present huge computational challenges, mostly…

Nonlinear parametric inverse problems appear in many applications. Here, we focus on diffuse optical tomography (DOT) in medical imaging to recover unknown images of interest, such as cancerous tissue in a given medium, using a mathematical…

Numerical Analysis · Mathematics 2020-07-14 Selin Aslan , Eric de Sturler , Serkan Gugercin

In ultrasound tomography, the speed of sound inside an object is estimated based on acoustic measurements carried out by sensors surrounding the object. An accurate forward model is a prominent factor for high-quality image reconstruction,…

Image and Video Processing · Electrical Eng. & Systems 2021-11-24 Janne Koponen , Timo Lähivaara , Jari Kaipio , Marko Vauhkonen

Bayesian inversion is central to the quantification of uncertainty within problems arising from numerous applications in science and engineering. To formulate the approach, four ingredients are required: a forward model mapping the unknown…

Machine Learning · Statistics 2025-05-15 O. Deniz Akyildiz , Mark Girolami , Andrew M. Stuart , Arnaud Vadeboncoeur

Inverse problems are important mathematical problems that seek to recover model parameters from noisy data. Since inverse problems are often ill-posed, they require regularization or incorporation of prior information about the underlying…

Numerical Analysis · Mathematics 2026-02-09 Oluwatosin Akande , Gabriel P. Langlois , Akwum Onwunta

Diffusion models have recently emerged as powerful generative priors for solving inverse problems. However, training diffusion models in the pixel space are both data-intensive and computationally demanding, which restricts their…

Computer Vision and Pattern Recognition · Computer Science 2024-04-17 Bowen Song , Soo Min Kwon , Zecheng Zhang , Xinyu Hu , Qing Qu , Liyue Shen

Recent efforts on solving inverse problems in imaging via deep neural networks use architectures inspired by a fixed number of iterations of an optimization method. The number of iterations is typically quite small due to difficulties in…

Image and Video Processing · Electrical Eng. & Systems 2021-06-04 Davis Gilton , Gregory Ongie , Rebecca Willett

The inverse medium problem, inherently ill-posed and nonlinear, presents significant computational challenges. This study introduces a novel approach by integrating a Neumann series structure within a neural network framework to effectively…

Mathematical Physics · Physics 2024-09-17 Ziyang Liu , Fukai Chen , Junqing Chen , Lingyun Qiu , Zuoqiang Shi

Recently, deep generative models have been used for posterior inference in inverse problems, including high-stakes applications in medical imaging and scientific discovery, where the uncertainty of a prediction can matter as much as the…

Machine Learning · Computer Science 2026-05-15 Yuxin Guo , Dongrui Deng , Pulkit Grover

In computational inverse problems, it is common that a detailed and accurate forward model is approximated by a computationally less challenging substitute. The model reduction may be necessary to meet constraints in computing time when…

Methodology · Statistics 2018-02-14 Daniela Calvetti , Matthew M. Dunlop , Erkki Somersalo , Andrew M. Stuart

Inverse problems arise anywhere we have indirect measurement. As, in general they are ill-posed, to obtain satisfactory solutions for them needs prior knowledge. Classically, different regularization methods and Bayesian inference based…

Machine Learning · Statistics 2023-08-31 Ali Mohammad-Djafari , Ning Chu , Li Wang , Liang Yu

In statistical inference, a discrepancy between the parameter-to-observable map that generates the data and the parameter-to-observable map that is used for inference can lead to misspecified likelihoods and thus to incorrect estimates. In…

Statistics Theory · Mathematics 2024-07-16 Nada Cvetković , Han Cheng Lie , Harshit Bansal , Karen Veroy

We consider a Bayesian nonparametric approach to a family of linear inverse problems in a separable Hilbert space setting with Gaussian noise. We assume Gaussian priors, which are conjugate to the model, and present a method of identifying…

Statistics Theory · Mathematics 2013-08-05 Sergios Agapiou , Stig Larsson , Andrew M. Stuart

This paper proposes a new method for estimating sparse precision matrices in the high dimensional setting. It has been popular to study fast computation and adaptive procedures for this problem. We propose a novel approach, called Sparse…

Methodology · Statistics 2016-12-23 Weidong Liu , Xi Luo

Computational imaging through scatter generally is accomplished by first characterizing the scattering medium so that its forward operator is obtained; and then imposing additional priors in the form of regularizers on the reconstruction…

Optics · Physics 2017-11-21 Shuai Li , Mo Deng , Justin Lee , Ayan Sinha , George Barbastathis

Transcranial ultrasound imaging is currently limited by attenuation and aberration induced by the skull. First used in contrast-enhanced ultrasound (CEUS), highly echoic microbubbles allowed for the development of novel imaging modalities…

Image and Video Processing · Electrical Eng. & Systems 2025-11-06 Paul Xing , Antoine Malescot , Eric Martineau , Ravi Rungta , Jean Provost

The recent development of compressed sensing has led to spectacular advances in the understanding of sparse linear estimation problems as well as in algorithms to solve them. It has also triggered a new wave of developments in the related…

Information Theory · Computer Science 2016-07-05 Christophe Schülke

Inverse problems challenge existing neural operator architectures because ill-posed inverse maps violate continuity, uniqueness, and stability assumptions. We introduce B2B${}^{-1}$, an inverse basis-to-basis neural operator framework that…

Machine Learning · Computer Science 2025-12-23 Adam J. Thorpe , Stepan Tretiakov , Dibakar Roy Sarkar , Krishna Kumar , Ufuk Topcu