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The identification of cancer genes is a critical yet challenging problem in cancer genomics research. Existing computational methods, including deep graph neural networks, fail to exploit the multilayered gene-gene interactions or provide…

Convolutional neural networks (CNN) have been frequently used to extract subject-invariant features from electroencephalogram (EEG) for classification tasks. This approach holds the underlying assumption that electrodes are equidistant…

Shallow Convolution Neural Network (CNN) is a time-tested tool for the information extraction from cancer pathology reports. Shallow CNN performs competitively on this task to other deep learning models including BERT, which holds the…

Renal compartment segmentation on CT images targets on extracting the 3D structure of renal compartments from abdominal CTA images and is of great significance to the diagnosis and treatment for kidney diseases. However, due to the unclear…

We develop a Causal-Deep Neural Network (CDNN) model trained in two stages to infer causal impact estimates at an individual unit level. Using only the pre-treatment features in stage 1 in the absence of any treatment information, we learn…

"Is it possible to predict expression levels of different genes at a given spatial location in the routine histology image of a tumor section by modeling its stain absorption characteristics?" In this work, we propose a "stain-aware"…

The Convolutional Neural Network (CNN) has achieved great success in image classification. The classification model can also be utilized at image or patch level for many other applications, such as object detection and segmentation. In this…

Understanding the morphological changes of primary neuronal cells induced by chemical compounds is essential for drug discovery. Using the data from a single high-throughput imaging assay, a classification model for predicting the…

The goal of exemplar-based texture synthesis is to generate texture images that are visually similar to a given exemplar. Recently, promising results have been reported by methods relying on convolutional neural networks (ConvNets)…

Structural alterations have been thoroughly investigated in the brain during the early onset of schizophrenia (SCZ) with the development of neuroimaging methods. The objective of the paper is an efficient classification of SCZ in 2…

Cell nuclei detection is a challenging research topic because of limitations in cellular image quality and diversity of nuclear morphology, i.e. varying nuclei shapes, sizes, and overlaps between multiple cell nuclei. This has been a topic…

Prostate cancer is one of the most common causes of cancer deaths in men. There is a growing demand for noninvasively and accurately diagnostic methods that facilitate the current standard prostate cancer risk assessment in clinical…

Graph Neural Networks (graph NNs) are a promising deep learning approach for analyzing graph-structured data. However, it is known that they do not improve (or sometimes worsen) their predictive performance as we pile up many layers and add…

Brainwave signals are read through Electroencephalogram (EEG) devices. These signals are generated from an active brain based on brain activities and thoughts. The classification of brainwave signals is a challenging task due to its…

Stress is one of the main issues of nowadays lifestyle. If it becomes chronic it can have adverse effects on the human body. Thus, the early detection of stress is crucial to prevent its hurting effects on the human body and have a…

Optimizing deep neural networks (DNNs) often suffers from the ill-conditioned problem. We observe that the scaling-based weight space symmetry property in rectified nonlinear network will cause this negative effect. Therefore, we propose to…

Convolutional neural networks (CNNs) have been established as the main workhorse in image data processing; nonetheless, they require large amounts of data to train, often produce overconfident predictions, and frequently lack the ability to…

The perceptual loss has been widely used as an effective loss term in image synthesis tasks including image super-resolution, and style transfer. It was believed that the success lies in the high-level perceptual feature representations…

An easily implementable path solution algorithm for 2D spatial problems, based on excitable/programmable characteristics of a specific cellular nonlinear network (CNN) model is presented and numerically investigated. The network is a single…

Few-shot image classification aims at recognizing unseen categories with a small number of labeled training data. Recent metric-based frameworks tend to represent a support class by a fixed prototype (e.g., the mean of the support category)…