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Machine learning (ML) continues to permeate all layers of academia, industry and society. Despite its successes, mental frameworks to capture and represent machine learning workflows in a consistent and coherent manner are lacking. For…

Software Engineering · Computer Science 2022-08-04 Laurens Martin Tetzlaff

The evolution of molecular dynamics (MD) simulations has been intimately linked to that of computing hardware. For decades following the creation of MD, simulations have improved with computing power along the three principal dimensions of…

Unified multimodal models (UMMs) that integrate understanding, reasoning, generation, and editing face inherent trade-offs between maintaining strong semantic comprehension and acquiring powerful generation capabilities. In this report, we…

Molecular simulations in an open environment, involving ion exchange, are necessary to study various systems, from biosystems to confined electrolytes. However, grand-canonical simulations are often computationally demanding in condensed…

Chemical Physics · Physics 2023-11-13 Jeongmi Kim , Luc Belloni , Benjamin Rotenberg

In this paper, we use support vector machines (SVM) to develop a machine learning framework to discover phase space structures that distinguish between distinct reaction pathways. The SVM model is trained using data from trajectories of…

Chemical Physics · Physics 2022-01-06 Vladimír Krajňák , Shibabrat Naik , Stephen Wiggins

We propose a hybrid meta-learning framework for forecasting and anomaly detection in nonlinear dynamical systems characterized by nonstationary and stochastic behavior. The approach integrates a physics-inspired simulator that captures…

Machine Learning · Computer Science 2025-06-18 Abdullah Burkan Bereketoglu

In this work we develop a model for an undamped vibration in the presence of an overdamped bath. This two-bath model involves a new derivation of the hierarchical equations of motion (HEOM) for an overdamped Lorentz-Drude (LD) environment…

Quantum Physics · Physics 2025-07-21 Ben S. Humphries , Dale Green , Garth A. Jones

The symmetrical quasi-classical dynamics method based on the Meyer-Miller mapping Hamiltonian (MM-SQC) shows the great potential in the treatment of the nonadiabatic dynamics of complex systems. We performed the comprehensive benchmark…

Chemical Physics · Physics 2019-03-12 Yu Xie , Jie Zheng , Zhenggang Lan

Unsupervised spectral unmixing consists of representing each observed pixel as a combination of several pure materials called endmembers with their corresponding abundance fractions. Beyond the linear assumption, various nonlinear unmixing…

Computer Vision and Pattern Recognition · Computer Science 2023-03-16 Tingting Fang , Fei Zhu , Jie Chen

Model merging aims to combine multiple task-specific expert models into a single model without joint retraining, offering a practical alternative to multi-task learning when data access or computational budget is limited. Existing methods,…

Machine Learning · Computer Science 2026-05-14 Kaiyang Li , Shaobo Han , Qing Su , Shihao Ji

The convergence of statistical learning and molecular physics is transforming our approach to modeling biomolecular systems. Physics-informed machine learning (PIML) offers a systematic framework that integrates data-driven inference with…

Biomolecules · Quantitative Biology 2025-11-11 Aaryesh Deshpande

Self-similarity is widely considered the reference framework for modeling the scaling properties of real-world data. However, most theoretical studies and their practical use have remained univariate. Operator Fractional Brownian Motion…

Probability · Mathematics 2016-09-07 Jordan Frecon , Gustavo Didier , Nelly Pustelnik , Patrice Abry

Simulations of biological macromolecules play an important role in understanding the physical basis of a number of complex processes such as protein folding. Even with increasing computational power and evolution of specialized…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-09-18 Hyungro Lee , Heng Ma , Matteo Turilli , Debsindhu Bhowmik , Shantenu Jha , Arvind Ramanathan

We propose a system identification method, Non-Markovian Optimization-based Modeling for Approximate Dynamics with Spatially-homogeneous memory (NOMADS), for identifying linear dynamical systems from a set of multi-dimensional time-series…

Optimization and Control · Mathematics 2026-01-27 Ryoji Anzaki , Kazuhiro Sato

In this work, we introduce a novel approach for predicting thermodynamic properties of binary mixtures, which we call the similarity-based method (SBM). The method is based on quantifying the pairwise similarity of components, which we…

Chemical Physics · Physics 2025-02-20 Nicolas Hayer , Thomas Specht , Justus Arweiler , Dominik Gond , Hans Hasse , Fabian Jirasek

Multimodal Large Language Models (MLLMs) are undergoing rapid progress and represent the frontier of AI development. However, their training and inference efficiency have emerged as a core bottleneck in making MLLMs more accessible and…

We present an open-source MLatom@XACS software ecosystem for on-the-fly surface hopping nonadiabatic dynamics based on the Landau-Zener-Belyaev-Lebedev (LZBL) algorithm. The dynamics can be performed via Python API with a wide range of…

Many-body localization (MBL), characterized by the absence of thermalization and the violation of conventional thermodynamics, has elicited much interest both as a fundamental physical phenomenon and for practical applications in quantum…

Disordered Systems and Neural Networks · Physics 2019-12-17 Pai Peng , Zeyang Li , Haoxiong Yan , Ken Xuan Wei , Paola Cappellaro

Prominent features of simulated moving bed (SMB) chromatography processes in the downstream processing is based on the determination of operating conditions. However, effects of different types of uncertainties have to be studied and…

Computational Engineering, Finance, and Science · Computer Science 2021-07-16 Qiao-Le He , Liming Zhao

We present a hybrid method for the simulation of colloidal systems, that combines molecular dynamics (MD) with the Lattice-Boltzmann (LB) scheme. The LB method is used as a model for the solvent in order to take into account the…

Soft Condensed Matter · Physics 2009-11-11 Apratim Chatterji , Juergen Horbach