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The hierarchical equations of motion (HEOM) provide a numerically exact approach for computing the reduced dynamics of a quantum system linearly coupled to a bath. We have found that HEOM contains temperature-dependent instabilities that…

Chemical Physics · Physics 2019-05-13 Ian S. Dunn , Roel Tempelaar , David R. Reichman

We present sMolBoxes, a dataflow representation for the exploration and analysis of long molecular dynamics (MD) simulations. When MD simulations reach millions of snapshots, a frame-by-frame observation is not feasible anymore. Thus,…

Quantitative Methods · Quantitative Biology 2022-10-04 Pavol Ulbrich , Manuela Waldner , Katarína Furmanová , Sérgio M. Marques , David Bednář , Barbora Kozlikova , Jan Byška

Efficient and accurate prediction of Multiphysics evolution across diverse cell geometries is fundamental to the design, management and safety of lithium-ion batteries. However, existing computational frameworks struggle to capture the…

Computational Engineering, Finance, and Science · Computer Science 2026-03-19 Zhiwei Zhao , Changqing Liu , Jie Lin , Fan Yang , Yifan Zhang , Yan Jin , Yingguang Li

Motivation: In systems biology, modelling strategies aim to decode how molecular components interact to generate dynamical behaviour. Boolean modelling is more and more used, but the description of the dynamics from two-levels components…

Molecular Networks · Quantitative Biology 2024-07-16 Nadine Ben Boina , Brigitte Mossé , Anaïs Baudot , Élisabeth Remy

Molecular Dynamics (MD) simulations are essential for understanding the atomic-level behavior of molecular systems, giving insights into their transitions and interactions. However, classical MD techniques are limited by the trade-off…

Biomolecules · Quantitative Biology 2026-04-21 Ziyang Yu , Wenbing Huang , Yang Liu

Methyl benzoate (MB) is studied as a model compound for the development of new IR pulse schemes with possible applicability to biomolecules. Anharmonic vibrational modes of MB are calculated on different level (MP2, SCS, CCSD(T) with…

Chemical Physics · Physics 2014-01-03 Kiran Sankar Maiti , Christoph Scheurer

A framework for performant Brownian Dynamics (BD) many-body simulations with adaptive timestepping is presented. Contrary to the Euler-Maruyama scheme in common non-adaptive BD, we employ an embedded Heun-Euler integrator for the…

Statistical Mechanics · Physics 2022-03-11 Florian Sammüller , Matthias Schmidt

This review article revisits and outlines the perfectly matched layer (PML) method and its various formulations developed over the past 25 years for the numerical modeling and simulation of wave propagation in unbounded media. Based on the…

Classical Physics · Physics 2021-04-21 Florent Pled , Christophe Desceliers

Machine learning (ML)-based steering can improve the performance of ensemble-based simulations by allowing for online selection of more scientifically meaningful computations. We present DeepDriveMD, a framework for ML-driven steering of…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-07-13 Alexander Brace , Igor Yakushin , Heng Ma , Anda Trifan , Todd Munson , Ian Foster , Arvind Ramanathan , Hyungro Lee , Matteo Turilli , Shantenu Jha

The powerful molecular dynamics (MD) simulation is basically based on a picture that the atoms experience classical-like trajectories under the exertion of classical force field determined by the quantum mechanically solved electronic…

Chemical Physics · Physics 2013-12-16 Wei Feng , Luting Xu , Xin-Qi Li , Weihai Fang

Rapid and accurate simulations of fluid dynamics around complicated geometric bodies are critical in a variety of engineering and scientific applications, including aerodynamics and biomedical flows. However, while scientific machine…

It is well known that the number of particles should be scaled up to enable industrial scale simulation. The calculations are more computationally intensive when the motion of the surrounding fluid is considered. Besides the advances in…

Computational Physics · Physics 2014-07-28 Hao Zhang , F. Xavier Trias , Assensi Oliva , Dongmin Yang , Yuanqiang Tan , Shi Shu , Yong Sheng

Modal synthesis methods are a long-standing approach for modelling distributed musical systems. In some cases extensions are possible in order to handle geometric nonlinearities. One such case is the high-amplitude vibration of a string,…

Sound · Computer Science 2025-05-16 Victor Zheleznov , Stefan Bilbao , Alec Wright , Simon King

Mixtures of linear dynamical systems (MoLDS) provide a path to model time-series data that exhibit diverse temporal dynamics across trajectories. However, its application remains challenging in complex and noisy settings, limiting its…

Machine Learning · Computer Science 2026-03-02 Lulu Gong , Shreya Saxena

We describe a framework for interactive molecular dynamics in a multiuser virtual reality environment, combining rigorous cloud-mounted physical atomistic simulation with commodity virtual reality hardware, which we have made accessible to…

Simulating atomic-scale processes, such as protein dynamics and catalytic reactions, is crucial for advancements in biology, chemistry, and materials science. Machine learning force fields (MLFFs) have emerged as powerful tools that achieve…

Chemical Physics · Physics 2024-12-30 Lars L. Schaaf , Ilyes Batatia , Christoph Brunken , Thomas D. Barrett , Jules Tilly

PiNNAcLe is an implementation of our adaptive learn-on-the-fly algorithm for running machine-learning potential (MLP)-based molecular dynamics (MD) simulations -- an emerging approach to simulate the large-scale and long-time dynamics of…

Statistical Mechanics · Physics 2024-09-16 Yunqi Shao , Chao Zhang

A proof-of-concept framework for identifying molecules of unknown elemental composition and structure using experimental rotational data and probabilistic deep learning is presented. Using a minimal set of input data determined…

Chemical Physics · Physics 2020-07-01 Michael C. McCarthy , Kin Long Kelvin Lee

Molecular dynamics (MD) simulations of ions (K$^+$, Na$^+$, Ca$^{2+}$ and Cl$^-$) in aqueous solutions are investigated. Water is described using the SPC/E model. A stochastic coarse-grained description for ion behaviour is presented and…

Computational Physics · Physics 2016-04-27 Radek Erban

This paper presents a hierarchical Bayesian modeling framework for the uncertainty quantification in modal identification of linear dynamical systems using multiple vibration data sets. This novel framework integrates the state-of-the-art…

Methodology · Statistics 2020-05-19 Omid Sedehi , Lambros S. Katafygiotis , Costas Papadimitriou
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