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Unsupervised learning methods are well established in the area of anomaly detection and achieve state of the art performances on outlier datasets. Outliers play a significant role, since they bear the potential to distort the predictions of…

Machine Learning · Computer Science 2024-07-02 Andreas Lohrer , Daniyal Kazempour , Maximilian Hünemörder , Peer Kröger

Conformal prediction is a flexible framework for calibrating machine learning predictions, providing distribution-free statistical guarantees. In outlier detection, this calibration relies on a reference set of labeled inlier data to…

Machine Learning · Statistics 2025-06-17 Meshi Bashari , Matteo Sesia , Yaniv Romano

The desire to train complex machine learning algorithms and to increase the statistical power in association studies drives neuroimaging research to use ever-larger datasets. The most obvious way to increase sample size is by pooling scans…

Computer Vision and Pattern Recognition · Computer Science 2020-10-29 Christian Wachinger , Anna Rieckmann , Sebastian Pölsterl

Functional magnetic resonance imaging (fMRI) data contain high levels of noise and artifacts. To avoid contamination of downstream analyses, fMRI-based studies must identify and remove these noise sources prior to statistical analysis. One…

Methodology · Statistics 2023-05-03 Fatma Parlak , Damon D. Pham , Amanda F. Mejia

Clinical machine learning applications are often plagued with confounders that are clinically irrelevant, but can still artificially boost the predictive performance of the algorithms. Confounding is especially problematic in mobile health…

Applications · Statistics 2018-11-29 Elias Chaibub Neto

Methods based on diffusion models (DMs) for solving inverse problems (IPs) have recently achieved remarkable performance. However, DM-based methods typically struggle against outliers, which are common in real-world measurements. In this…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Yang Zheng , Jiahua Liu , Tongyao Pang , Wen Li , Zhaoqiang Liu

Outliers widely occur in big-data applications and may severely affect statistical estimation and inference. In this paper, a framework of outlier-resistant estimation is introduced to robustify an arbitrarily given loss function. It has a…

Methodology · Statistics 2023-04-20 Yiyuan She , Zhifeng Wang , Jiahui Shen

Deep neural networks are increasingly being used to detect and diagnose medical conditions using medical imaging. Despite their utility, these models are highly vulnerable to adversarial attacks and distribution shifts, which can affect…

Image and Video Processing · Electrical Eng. & Systems 2025-06-23 Josué Martínez-Martínez , Olivia Brown , Mostafa Karami , Sheida Nabavi

In diagnostic test accuracy meta-analysis (DTA-MA), standard inference methods using bivariate random-effects models for jointly synthesizing sensitivity and specificity can be sensitive to outlying studies and may yield misleading…

Methodology · Statistics 2026-05-01 Kotaro Sasaki , Hisashi Noma , Theodoros Evrenoglou

Linear mixed models (LMMs) are a popular class of methods for analyzing longitudinal and clustered data. However, such models can be sensitive to outliers, and this can lead to biased inference on model parameters and inaccurate prediction…

Methodology · Statistics 2025-03-28 Shonosuke Sugasawa , Francis K. C. Hui , Alan H. Welsh

Owing to its pristine soft-tissue contrast and high resolution, structural magnetic resonance imaging (MRI) is widely applied in neurology, making it a valuable data source for image-based machine learning (ML) and deep learning…

Image and Video Processing · Electrical Eng. & Systems 2021-11-18 Merel Kuijs , Catherine R. Jutzeler , Bastian Rieck , Sarah C. Brüningk

Data harmonization is the process by which an equivalence is developed between two variables measuring a common trait. Our problem is motivated by dementia research in which multiple tests are used in practice to measure the same underlying…

Methodology · Statistics 2021-10-13 Steven Wilkins-Reeves , Yen-Chi Chen , Kwun Chuen Gary Chan

In many machine learning tasks, a common approach for dealing with large-scale data is to build a small summary, {\em e.g.,} coreset, that can efficiently represent the original input. However, real-world datasets usually contain outliers…

Machine Learning · Computer Science 2022-01-24 Zixiu Wang , Yiwen Guo , Hu Ding

This paper deals with the problem of outliers in high frequency observation data from diffusion processes. Robust estimation methods are needed because the inclusion of outliers can lead to incorrect statistical inference even in the…

Methodology · Statistics 2026-03-06 Tomoyuki Nakagawa , Yusuke Shimizu

Multi-center neuroimaging studies face technical variability due to batch differences across sites, which potentially hinders data aggregation and impacts study reliability.Recent efforts in neuroimaging harmonization have aimed to minimize…

Computer Vision and Pattern Recognition · Computer Science 2024-09-04 Haoyu Lan , Bino A. Varghese , Nasim Sheikh-Bahaei , Farshid Sepehrband , Arthur W Toga , Jeiran Choupan

Randomized controlled trials (RCTs) are the gold standard for estimating heterogeneous treatment effects, yet they are often underpowered for detecting effect heterogeneity. Large observational studies (OS) can supplement RCTs for…

Machine Learning · Computer Science 2026-04-07 Amir Asiaee , Samhita Pal

Supervised learning models are challenged by the intrinsic complexities of training data such as outliers and minority subpopulations and intentional attacks at inference time with adversarial samples. While traditional robust learning…

Machine Learning · Computer Science 2023-09-12 Shu Hu , Zhenhuan Yang , Xin Wang , Yiming Ying , Siwei Lyu

In this article, we consider the problem of outlier-robust state estimation where the measurement noise can be correlated. Outliers in data arise due to many reasons like sensor malfunctioning, environmental behaviors, communication…

Signal Processing · Electrical Eng. & Systems 2024-08-21 Aamir Hussain Chughtai , Muhammad Tahir , Momin Uppal

Magnetic resonance imaging (MRI) has greatly advanced neuroscience research and clinical diagnostics. However, imaging data collected across different scanners, acquisition protocols, or imaging sites often exhibit substantial…

Image and Video Processing · Electrical Eng. & Systems 2026-04-02 Qinqin Yang , Firoozeh Shomal-Zadeh , Ali Gholipour

When applying a statistical method in practice it often occurs that some observations deviate from the usual assumptions. However, many classical methods are sensitive to outliers. The goal of robust statistics is to develop methods that…

Methodology · Statistics 2008-08-06 Mia Hubert , Peter J. Rousseeuw , Stefan Van Aelst