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Hybrid quantum-classical applications pose significant resource management challenges due to heterogeneity and dynamism in both infrastructure and workloads. Quantum-HPC environments integrate quantum processing units (QPUs) with diverse…

Quantum Physics · Physics 2026-04-07 Pradeep Mantha , Florian J. Kiwit , Nishant Saurabh , Shantenu Jha , Andre Luckow

Quantum machine learning has emerged as a promising approach for medical image analysis, particularly in settings where compact models and expressive feature representations are desired. This paper presents a hybrid classical--quantum…

Computer Vision and Pattern Recognition · Computer Science 2026-05-01 Shabnam Sodagari , Tommy Long

Current quantum systems have significant limitations affecting the processing of large datasets with high dimensionality, typical of high energy physics. In the present paper, feature and data prototype selection techniques were studied to…

High Energy Physics - Phenomenology · Physics 2023-12-18 Miguel Caçador Peixoto , Nuno Filipe Castro , Miguel Crispim Romão , Maria Gabriela Jordão Oliveira , Inês Ochoa

We present a comprehensive study of the commute time kernel method via the effective resistance framework analyzing the quantum complexity of the originally classical approach. Our study reveals that while there is a trade-off between…

Quantum Physics · Physics 2026-01-06 Adam Wesołowski , Karim Essafi

We demonstrate the feasibility of quantum computing for large-scale, realistic chemical systems through the development of a new interface using a quantum circuit simulator and CP2K, a highly efficient first-principles calculation software.…

Chemical Physics · Physics 2025-06-24 Tomoya Shiota , Klaas Gunst , Toshio Mori , Toru Shiozaki , Wataru Mizukami

A sophisticated hybrid quantum convolutional neural network (HQCNN) is conceived for handling the pilot assignment task in cell-free massive MIMO systems, while maximizing the total ergodic sum throughput. The existing model-based solutions…

Information Theory · Computer Science 2025-07-10 Doan Hieu Nguyen , Xuan Tung Nguyen , Seon-Geun Jeong , Trinh Van Chien , Lajos Hanzo , Won Joo Hwang

Quantum Computers offer an intriguing challenge in modern Computer Science. With the inevitable physical limitations to Moore's Law, quantum hardware provides avenues to solve grander problems faster by utilizing Quantum Mechanical…

Emerging Technologies · Computer Science 2024-07-17 Samuel T. Bieberich , Ketan C. Maheshwari , Sean R. Wilkinson , Prasanna Date , In-Saeng Suh , Rafael Ferreira da Silva

Ab initio wavefunction methods provide accurate molecular simulations but their computational scaling restricts applications to small systems. We develop a workflow combining quantum embedding to decompose a molecule into fragments with a…

Quantum computing is moving beyond its early stage and seeking for commercial applications in chemical and biomedical sciences. In the current noisy intermediate-scale quantum computing era, quantum resource is too scarce to support these…

Quantum Physics · Physics 2023-03-08 Honghui Shang , Yi Fan , Li Shen , Chu Guo , Jie Liu , Xiaohui Duan , Fang Li , Zhenyu Li

Clinical trials are pivotal in the drug discovery process to determine the safety and efficacy of a drug candidate. The high failure rates of these trials are attributed to deficiencies in clinical model development and protocol design.…

The search for meaningful structure in biological data has relied on cutting-edge advances in computational technology and data science methods. However, challenges arise as we push the limits of scale and complexity in biological problems.…

Quantum machine learning (QML) presents potential for early industrial adoption, yet limited access to quantum hardware remains a significant bottleneck for deployment of QML solutions. This work explores the use of classical surrogates to…

Quantum machine learning is a rapidly growing field at the intersection of quantum technology and artificial intelligence. This review provides a two-fold overview of several key approaches that can offer advancements in both the…

Quantum Physics · Physics 2023-03-07 Alexey Melnikov , Mohammad Kordzanganeh , Alexander Alodjants , Ray-Kuang Lee

With the growing complexity of computational and experimental facilities, many scientific researchers are turning to machine learning (ML) techniques to analyze large scale ensemble data. With complexities such as multi-component workflows,…

Quantum computing is a promising paradigm that may overcome the current computational power bottlenecks. The increasing maturity of quantum processors provides more possibilities for the development and implementation of quantum algorithms.…

Quantum Physics · Physics 2025-10-15 Ge Yan , Wenjie Wu , Yuheng Chen , Kaisen Pan , Xudong Lu , Zixiang Zhou , Yuhan Wang , Ruocheng Wang , Junchi Yan

Hybrid quantum-high performance computing (Q-HPC) workflows are emerging as a key strategy for running quantum applications at scale in current noisy intermediate-scale quantum (NISQ) devices. These workflows must operate seamlessly across…

The convergence of HPC and data-intensive methodologies provide a promising approach to major performance improvements. This paper provides a general description of the interaction between traditional HPC and ML approaches and motivates the…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-03-01 Geoffrey Fox , James A. Glazier , JCS Kadupitiya , Vikram Jadhao , Minje Kim , Judy Qiu , James P. Sluka , Endre Somogyi , Madhav Marathe , Abhijin Adiga , Jiangzhuo Chen , Oliver Beckstein , Shantenu Jha

Recent advances in high-throughput genomic technologies coupled with exponential increases in computer processing and memory have allowed us to interrogate the complex aberrant molecular underpinnings of human disease from a genome-wide…

Cancer is one of the leading causes of death worldwide. It is caused by a variety of genetic mutations, which makes every instance of the disease unique. Since chemotherapy can have extremely severe side effects, each patient requires a…

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