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The biological membrane, which compartmentalizes the cell and its organelles, exhibit wide variety of macroscopic shapes of varying morphology and topology. A systematic understanding of the relation of membrane shapes to composition,…

Biological Physics · Physics 2011-09-23 N. Ramakrishnan , P. B. Sunil Kumar , John H. Ipsen

Human pluripotent stem cells (hPSCs) have promising clinical applications in regenerative medicine, drug-discovery and personalised medicine due to their potential to differentiate into all cell types, a property know as pluripotency. A…

Subcellular Processes · Quantitative Biology 2021-02-26 L E Wadkin , S Orozco-Fuentes , I Neganova , M Lako , N G Parker , A Shukurov

The determination of potentials of mean force for solute insertion in a membrane by means of all-atom molecular dynamics simulations is often hampered by sampling issues. A multiscale approach to conformational sampling was recently…

Chemical Physics · Physics 2017-10-09 Roberto Menichetti , Kurt Kremer , Tristan Bereau

The design and engineering of molecular communication (MC) components capable of processing chemical concentration signals is the key to unleashing the potential of MC for interdisciplinary applications. By controlling the signaling pathway…

Information Theory · Computer Science 2023-10-19 Rinrada Jadsadaphongphaibool , Dadi Bi , Yansha Deng

Metasurface-generated holography has emerged as a promising route for fully reproducing vivid scenes by manipulating the optical properties of light using ultra-compact devices. However, achieving multiple holographic images using a single…

This paper investigates a cell-free massive MIMO (multiple-input multiple-output) system where distributed access points (APs) perform integrated sensing and communications (ISAC) tasks, enabling simultaneous user communication and target…

Information Theory · Computer Science 2025-03-11 Sergi Liesegang , Stefano Buzzi , Carmen D'Andrea

We present Implicit-Scale 3D Reconstruction from Monocular Multi-Food Images, a benchmark dataset designed to advance geometry-based food portion estimation in realistic dining scenarios. Existing dietary assessment methods largely rely on…

Computer Vision and Pattern Recognition · Computer Science 2026-02-16 Yuhao Chen , Gautham Vinod , Siddeshwar Raghavan , Talha Ibn Mahmud , Bruce Coburn , Jinge Ma , Fengqing Zhu , Jiangpeng He

Epigenetic Tracking is a mathematical model of biological cells, originally conceived to study embryonic development. Computer simulations proved the capacity of the model to generate complex 3-dimensional cellular structures, and the…

Cell Behavior · Quantitative Biology 2015-07-07 Alessandro Fontana

Multilayer networks allow one to represent diverse and coupled connectivity patterns --- e.g., time-dependence, multiple subsystems, or both --- that arise in many applications and which are difficult or awkward to incorporate into standard…

Social and Information Networks · Computer Science 2020-05-06 Marya Bazzi , Lucas G. S. Jeub , Alex Arenas , Sam D. Howison , Mason A. Porter

A wide variety of real random composites can be studied by means of prototypes of multiphase microstructures with a controllable spatial inhomogeneity. To create them, we propose a versatile model of randomly overlapping super-spheres of a…

Materials Science · Physics 2017-09-26 D. Frączek , R. Piasecki , W. Olchawa , R. Wiśniowski

The inverse design of metasurfaces faces inherent challenges due to the nonlinear and highly complex relationship between geometric configurations and their electromagnetic behavior. Traditional optimization approaches often suffer from…

The development of novel pharmaceuticals represents a significant challenge in modern science, with substantial costs and time investments. Deep generative models have emerged as promising tools for accelerating drug discovery by…

Atomic Physics · Physics 2025-05-20 Adarsh Singh

The intentional growth of metastable surface structures of organic molecules adsorbed on inorganic substrates is a challenging task. It is usually unclear which kinetic mechanism leads to the metastable surface polymorph after a deposition…

Materials Science · Physics 2025-07-18 Simon B. Hollweger , Anna Werkovits , Oliver T. Hofmann

A critical step in tissue engineering is the design and synthesis of 3D biocompatible matrices (scaffolds) to support and guide the proliferation of cells and tissue growth. Most existing techniques rely on the processing of scaffolds under…

Soft Condensed Matter · Physics 2020-06-16 C. S. Dias , C. A. Custodio , G. C. Antunes , M. M. Telo da Gama , J. F. Mano , N. A. M. Araujo

We develop an automated computational modeling framework for rapid gradient-based design of multistable soft mechanical structures composed of non-identical bistable unit cells with appropriate geometric parameterization. This framework…

Numerical Analysis · Mathematics 2023-09-12 Mehran Mirramezani , Deniz Oktay , Ryan P. Adams

The dynamics of cellular aggregates is driven by the interplay of mechanochemical processes and cellular activity. Although deterministic models may capture mechanical features, local chemical fluctuations trigger random cell responses,…

Soft Condensed Matter · Physics 2024-01-17 Ana Carpio , Elena Cebrian

Performing long-term experimentation or large-scale data collection for machine learning in the field of soft robotics is challenging, due to the hardware robustness and experimental flexibility required. In this work, we propose a modular…

Robotics · Computer Science 2024-09-06 Kiyn Chin , Carmel Majidi , Abhinav Gupta

Physical interactive robotics, ranging from wearable devices to collaborative humanoid robots, require close coordination between mechanical design and control. However, evaluating interactive dynamics is challenging due to complex human…

Robotics · Computer Science 2026-03-11 Chenhui Zuo , Jinhao Xu , Michael Qian Vergnolle , Yanan Sui

The phase field model can accurately simulate the evolution of microstructures with complex morphologies, and it has been widely used for cell modeling in the last two decades. However, compared to other cellular models such as the…

Biological Physics · Physics 2022-06-13 Xiangyu Kuang , Guoye Guan , Chao Tang , Lei Zhang

Encapsulation of chemicals using polymer membranes enables to control their transport and delivery for applications such as agrochemistry or detergency. To rationalize the design of polymer capsules, it is necessary to understand how the…

Soft Condensed Matter · Physics 2018-12-18 Corentin Tregouët , Thomas Salez , Mathilde Reyssat , Cécile Monteux