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Predicting the response of a specific cancer to a therapy is a major goal in modern oncology that should ultimately lead to a personalised treatment. High-throughput screenings of potentially active compounds against a panel of genomically…

Lung cancer has been one of the most prevalent disease in recent years. According to the research of this field, more than 200,000 cases are identified each year in the US. Uncontrolled multiplication and growth of the lung cells result in…

Image and Video Processing · Electrical Eng. & Systems 2022-01-04 Hesamoddin Hosseini , Reza Monsefi , Shabnam Shadroo

The recent development of imaging and sequencing technologies enables systematic advances in the clinical study of lung cancer. Meanwhile, the human mind is limited in effectively handling and fully utilizing the accumulation of such…

Machine Learning · Computer Science 2022-03-29 Yawei Li , Xin Wu , Ping Yang , Guoqian Jiang , Yuan Luo

Understanding how deep learning models predict oncology patient risk can provide critical insights into disease progression, support clinical decision-making, and pave the way for trustworthy and data-driven precision medicine. Building on…

Computer Vision and Pattern Recognition · Computer Science 2024-11-13 Marvin Sextro , Gabriel Dernbach , Kai Standvoss , Simon Schallenberg , Frederick Klauschen , Klaus-Robert Müller , Maximilian Alber , Lukas Ruff

Radiation response in cancer is shaped by complex, patient specific biology, yet current treatment strategies often rely on uniform dose prescriptions without accounting for tumor heterogeneity. In this study, we introduce a meta learning…

Medical Physics · Physics 2025-08-12 Hao Peng , Yuanyuan Zhang , Steve Jiang , Robert Timmerman , John Minna

Lung cancer is a major issue in worldwide public health, requiring early diagnosis using stable techniques. This work begins a thorough investigation of the use of machine learning (ML) methods for precise classification of lung cancer…

Computer Vision and Pattern Recognition · Computer Science 2025-01-31 Shayli Farshchiha , Salman Asoudeh , Maryam Shavali Kuhshuri , Mehrshad Eisaeid , Mohamadreza Azadie , Saba Hesaraki

Since, cancer is curable when diagnosed at an early stage, lung cancer screening plays an important role in preventive care. Although both low dose computed tomography (LDCT) and computed tomography (CT) scans provide more medical…

Image and Video Processing · Electrical Eng. & Systems 2020-07-28 Worawate Ausawalaithong , Sanparith Marukatat , Arjaree Thirach , Theerawit Wilaiprasitporn

Lung cancer remains one of the most prevalent and fatal diseases worldwide, demanding accurate and timely diagnosis and treatment. Recent advancements in large AI models have significantly enhanced medical image understanding and clinical…

Image and Video Processing · Electrical Eng. & Systems 2025-07-01 Jiachen Zhong , Yiting Wang , Di Zhu , Ziwei Wang

Lung cancer is the leading cause of cancer death and morbidity worldwide. Many studies have shown machine learning models to be effective at detecting lung nodules from chest X-ray images. However, these techniques have yet to be embraced…

Image and Video Processing · Electrical Eng. & Systems 2021-08-31 Michael J. Horry , Subrata Chakraborty , Biswajeet Pradhan , Manoranjan Paul , Douglas P. S. Gomes , Anwaar Ul-Haq

In this proposed work, we identified the significant research issues on lung cancer risk factors. Capturing and defining symptoms at an early stage is one of the most difficult phases for patients. Based on the history of patients records,…

Image and Video Processing · Electrical Eng. & Systems 2023-04-12 Muhammad Sohaib , Mary Adewunmi

Gene expression profiles obtained through DNA microarray have proven successful in providing critical information for cancer detection classifiers. However, the limited number of samples in these datasets poses a challenge to employ complex…

Machine Learning · Computer Science 2024-08-20 Arya Hadizadeh Moghaddam , Mohsen Nayebi Kerdabadi , Cuncong Zhong , Zijun Yao

Cancer claims millions of lives yearly worldwide. While many therapies have been made available in recent years, by in large cancer remains unsolved. Exploiting computational predictive models to study and treat cancer holds great promise…

Quantitative Methods · Quantitative Biology 2022-11-22 Alexander Partin , Thomas S. Brettin , Yitan Zhu , Oleksandr Narykov , Austin Clyde , Jamie Overbeek , Rick L. Stevens

Cancer is a term that denotes a group of diseases caused by abnormal growth of cells that can spread in different parts of the body. According to the World Health Organization (WHO), cancer is the second major cause of death after…

Machine Learning · Computer Science 2023-01-31 Fadi Alharbi , Aleksandar Vakanski

Early detection of lung cancer is critical to improving survival outcomes. We present a deep learning framework for automated lung cancer screening from chest computed tomography (CT) images with integrated explainability. Using the…

Image and Video Processing · Electrical Eng. & Systems 2026-01-07 Nishan Rai , Sujan Khatri , Devendra Risal

Deep learning has shown remarkable results for image analysis and is expected to aid individual treatment decisions in health care. To achieve this, deep learning methods need to be promoted from the level of mere associations to being able…

Machine Learning · Computer Science 2022-05-02 Wouter A. C. van Amsterdam , Marinus J. C. Eijkemans

This paper explores interpretability techniques for two of the most successful learning algorithms in medical decision-making literature: deep neural networks and random forests. We applied these algorithms in a real-world medical dataset…

Machine Learning · Computer Science 2020-02-24 Catarina Moreira , Renuka Sindhgatta , Chun Ouyang , Peter Bruza , Andreas Wichert

Interpretability of deep learning is widely used to evaluate the reliability of medical imaging models and reduce the risks of inaccurate patient recommendations. For models exceeding human performance, e.g. predicting RNA structure from…

Quantitative Methods · Quantitative Biology 2022-08-31 Mara Graziani , Niccolò Marini , Nicolas Deutschmann , Nikita Janakarajan , Henning Müller , María Rodríguez Martínez

Lung cancer is the leading cause of death among different types of cancers. Every year, the lives lost due to lung cancer exceed those lost to pancreatic, breast, and prostate cancer combined. The survival rate for lung cancer patients is…

Image and Video Processing · Electrical Eng. & Systems 2023-02-17 Saleh Abunajm , Nelly Elsayed , Zag ElSayed , Murat Ozer

Metastasis is the leading cause of cancer-related mortality, yet most predictive models rely on shallow architectures and neglect patient-specific regulatory mechanisms. Here, we integrate classical machine learning and deep learning to…

Other Quantitative Biology · Quantitative Biology 2025-12-29 Jiwei Fu , Chunyu Yang

Cancer is one of the most common diseases worldwide, posing a serious threat to human health and leading to the deaths of a large number of people. It was observed during the drug administration in chemotherapy that immune cells, cancer…

Quantitative Methods · Quantitative Biology 2020-08-20 SeyedMehdi Abtahi , Mojtaba Sharifi
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