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Discriminating lung nodules as malignant or benign is still an underlying challenge. To address this challenge, radiologists need computer aided diagnosis (CAD) systems which can assist in learning discriminative imaging features…

Computer Vision and Pattern Recognition · Computer Science 2018-10-15 Maria J. M. Chuquicusma , Sarfaraz Hussein , Jeremy Burt , Ulas Bagci

Lung cancer is a major cause of cancer-related deaths, and early diagnosis and treatment are crucial for improving patients' survival outcomes. In this paper, we propose to employ convolutional neural networks to model the non-linear…

Image and Video Processing · Electrical Eng. & Systems 2024-08-20 Xiawei Wang , James Sharpnack , Thomas C. M. Lee

Generative AI framework-based modeling and prediction of longitudinal human brain images offer an efficient mechanism to track neurodegenerative progression, essential for the assessment of diseases like Alzheimer's. Among the existing…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Ayantika Das , Keerthi Ram , Mohanasankar Sivaprakasam

Early detection of lung cancer is essential in reducing mortality. Recent studies have demonstrated the clinical utility of low-dose computed tomography (CT) to detect lung cancer among individuals selected based on very limited clinical…

Computer Vision and Pattern Recognition · Computer Science 2019-02-25 Jiachen Wang , Riqiang Gao , Yuankai Huo , Shunxing Bao , Yunxi Xiong , Sanja L. Antic , Travis J. Osterman , Pierre P. Massion , Bennett A. Landman

Lung cancer remains one of the leading causes of cancer-related mortality worldwide, with early and accurate diagnosis playing a pivotal role in improving patient outcomes. Automated detection of pulmonary nodules in computed tomography…

Computer Vision and Pattern Recognition · Computer Science 2025-04-10 Abhinav Roy , Bhavesh Gyanchandani , Aditya Oza

Lung adenocarcinoma (LUAD) is a morphologically heterogeneous disease, characterized by five primary histological growth patterns. The classification of such patterns is crucial due to their direct relation to prognosis but the high…

Image and Video Processing · Electrical Eng. & Systems 2025-01-15 Arwa Al-Rubaian , Gozde N. Gunesli , Wajd A. Althakfi , Ayesha Azam , David Snead , Nasir M. Rajpoot , Shan E Ahmed Raza

Pulmonary nodule detection plays an important role in lung cancer screening with low-dose computed tomography (CT) scans. It remains challenging to build nodule detection deep learning models with good generalization performance due to…

Computer Vision and Pattern Recognition · Computer Science 2020-02-10 Yuemeng Li , Yong Fan

Detection of pulmonary nodules in chest CT imaging plays a crucial role in early diagnosis of lung cancer. Manual examination is highly time-consuming and error prone, calling for computer-aided detection, both to improve efficiency and…

Computer Vision and Pattern Recognition · Computer Science 2018-07-17 Zhongliu Xie

Existing learning models often utilise CT-scan images to predict lung diseases. These models are posed by high uncertainties that affect lung segmentation and visual feature learning. We introduce MARL, a novel Multimodal Attentional…

Computer Vision and Pattern Recognition · Computer Science 2021-05-04 Ali Hamdi , Amr Aboeleneen , Khaled Shaban

The spatial distributions of different types of cells could reveal a cancer cell growth pattern, its relationships with the tumor microenvironment and the immune response of the body, all of which represent key hallmarks of cancer. However,…

Computer Vision and Pattern Recognition · Computer Science 2018-09-28 Shidan Wang , Tao Wang , Lin Yang , Faliu Yi , Xin Luo , Yikun Yang , Adi Gazdar , Junya Fujimoto , Ignacio I. Wistuba , Bo Yao , ShinYi Lin , Yang Xie , Yousheng Mao , Guanghua Xiao

The ability of deep learning to predict with uncertainty is recognized as key for its adoption in clinical routines. Moreover, performance gain has been enabled by modelling uncertainty according to empirical evidence. While previous work…

Computer Vision and Pattern Recognition · Computer Science 2021-02-09 Jiawei Yang , Yuan Liang , Yao Zhang , Weinan Song , Kun Wang , Lei He

We are developing a computer-aided detection (CAD) system for the identification of small pulmonary nodules in screening CT scans. The main modules of our system, i.e. a dot-enhancement filter for nodule candidate selection and a neural…

Medical Physics · Physics 2009-04-15 P. Delogu , M. E. Fantacci , I. Gori , A. Preite Martinez , A. Retico , A. Tata

Detection of pulmonary nodules by CT is used for screening lung cancer in early stages.omputer aided diagnosis (CAD) based on deep-learning method can identify the suspected areas of pulmonary nodules in CT images, thus improving the…

Image and Video Processing · Electrical Eng. & Systems 2023-03-24 Yang Liu , Yue-Jie Hou , Chen-Xin Qin , Xin-Hui Li , Si-Jing Li , Bin Wang , Chi-Chun Zhou

Objective: In clinical practice, small lung nodules can be easily overlooked by radiologists. The paper aims to provide an efficient and accurate detection system for small lung nodules while keeping good performance for large nodules.…

Image and Video Processing · Electrical Eng. & Systems 2021-06-09 Sunyi Zheng , Ludo J. Cornelissen , Xiaonan Cui , Xueping Jing , Raymond N. J. Veldhuis , Matthijs Oudkerk , Peter M. A. van Ooijen

In this work, we introduce Brain Latent Progression (BrLP), a novel spatiotemporal disease progression model based on latent diffusion. BrLP is designed to predict the evolution of diseases at the individual level on 3D brain MRIs. Existing…

Computer Vision and Pattern Recognition · Computer Science 2025-07-15 Lemuel Puglisi , Daniel C. Alexander , Daniele Ravì

Recent studies show that deep learning models achieve good performance on medical imaging tasks such as diagnosis prediction. Among the models, multimodality has been an emerging trend, integrating different forms of data such as chest…

Machine Learning · Computer Science 2022-02-10 Haodi Zhang , Chenyu Xu , Peirou Liang , Ke Duan , Hao Ren , Weibin Cheng , Kaishun Wu

Although diffusion models have achieved remarkable progress in multi-modal magnetic resonance imaging (MRI) translation tasks, existing methods still tend to suffer from anatomical inconsistencies or degraded texture details when handling…

Image and Video Processing · Electrical Eng. & Systems 2026-03-16 Jianqiang Lin , Zhiqiang Shen , Peng Cao , Jinzhu Yang , Osmar R. Zaiane , Xiaoli Liu

Generative data augmentation with latent diffusion models is a promising strategy for addressing class imbalance in medical imaging, yet current approaches focus on perceptual fidelity and domain-specific autoencoder fine-tuning while…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Mischa Dombrowski , Felix Nützel , Bernhard Kainz

Medical image analysis relies on accurate segmentation, and benefits from controllable synthesis (of new training images). Yet both tasks of the cyclical pipeline face spatial imbalance: lesions occupy small regions against vast…

Computer Vision and Pattern Recognition · Computer Science 2026-03-06 Anugunj Naman , Ayushman Singh , Gaibo Zhang , Yaguang Zhang

PURPOSE: This study aimed to develop a deep learning-based tool to detect and localize lung nodules with chest radiographs(CXRs). We expected it to enhance the efficiency of interpreting CXRs and reduce the possibilities of delayed…

Image and Video Processing · Electrical Eng. & Systems 2022-03-14 Yang Tai , Yu-Wen Fang , Fang-Yi Su , Jung-Hsien Chiang