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Lung cancer classification in screening computed tomography (CT) scans is one of the most crucial tasks for early detection of this disease. Many lives can be saved if we are able to accurately classify malignant/cancerous lung nodules.…

Image and Video Processing · Electrical Eng. & Systems 2021-09-20 Mundher Al-Shabi , Kelvin Shak , Maxine Tan

Lung cancer is the leading cause of cancer-related death worldwide. Early diagnosis of pulmonary nodules in Computed Tomography (CT) chest scans provides an opportunity for designing effective treatment and making financial and care plans.…

Computer Vision and Pattern Recognition · Computer Science 2018-06-19 Raunak Dey , Zhongjie Lu , Yi Hong

Early detection of lung cancer has been proven to decrease mortality significantly. A recent development in computed tomography (CT), spectral CT, can potentially improve diagnostic accuracy, as it yields more information per scan than…

Computer Vision and Pattern Recognition · Computer Science 2020-07-01 Linde S. Hesse , Pim A. de Jong , Josien P. W. Pluim , Veronika Cheplygina

Different types of Convolutional Neural Networks (CNNs) have been applied to detect cancerous lung nodules from computed tomography (CT) scans. However, the size of a nodule is very diverse and can range anywhere between 3 and 30…

Computer Vision and Pattern Recognition · Computer Science 2019-12-17 Mundher Al-Shabi , Hwee Kuan Lee , Maxine Tan

This study proposes a novel approach combining Multimodal Deep Learning with intrinsic eXplainable Artificial Intelligence techniques to predict pathological response in non-small cell lung cancer patients undergoing neoadjuvant therapy.…

Computer Vision and Pattern Recognition · Computer Science 2026-02-16 Alice Natalina Caragliano , Claudia Tacconi , Carlo Greco , Lorenzo Nibid , Edy Ippolito , Michele Fiore , Giuseppe Perrone , Sara Ramella , Paolo Soda , Valerio Guarrasi

Lung cancer is the deadliest type of cancer worldwide and late detection is the major factor for the low survival rate of patients. Low dose computed tomography has been suggested as a potential screening tool but manual screening is…

Recently, computer-aided diagnosis systems have been developed to support diagnosis, but their performance depends heavily on the quality and quantity of training data. However, in clinical practice, it is difficult to collect the large…

Image and Video Processing · Electrical Eng. & Systems 2026-01-19 Kaito Urata , Maiko Nagao , Atsushi Teramoto , Kazuyoshi Imaizumi , Masashi Kondo , Hiroshi Fujita

Since radiologists have different training and clinical experiences, they may provide various segmentation annotations for a lung nodule. Conventional studies choose a single annotation as the learning target by default, but they waste…

Image and Video Processing · Electrical Eng. & Systems 2022-06-08 Han Yang , Lu Shen , Mengke Zhang , Qiuli Wang

This paper proposes a novel and efficient method to build a Computer-Aided Diagnoses (CAD) system for lung nodule detection based on Computed Tomography (CT). This task was treated as an Object Detection on Video (VID) problem by imitating…

Computer Vision and Pattern Recognition · Computer Science 2017-12-15 Ning Li , Haopeng Liu , Bin Qiu , Wei Guo , Shijun Zhao , Kungang Li , Jie He

Early detection of pulmonary nodules in computed tomography (CT) images is essential for successful outcomes among lung cancer patients. Much attention has been given to deep convolutional neural network (DCNN)-based approaches to this…

Computer Vision and Pattern Recognition · Computer Science 2019-03-26 Hao Tang , Daniel R. Kim , Xiaohui Xie

Diagnosing lung cancer typically involves physicians identifying lung nodules in Computed tomography (CT) scans and generating diagnostic reports based on their morphological features and medical expertise. Although advancements have been…

Computer Vision and Pattern Recognition · Computer Science 2025-11-27 Cheng Yang , Hui Jin , Xinlei Yu , Zhipeng Wang , Yaoqun Liu , Fenglei Fan , Dajiang Lei , Gangyong Jia , Changmiao Wang , Ruiquan Ge

The field of lung nodule detection and cancer prediction has been rapidly developing with the support of large public data archives. Previous studies have largely focused on cross-sectional (single) CT data. Herein, we consider longitudinal…

Recently, lung nodule detection methods based on deep learning have shown excellent performance in the medical image processing field. Considering that only a few public lung datasets are available and lung nodules are more difficult to…

Image and Video Processing · Electrical Eng. & Systems 2024-03-08 Yujiang Chen , Mei Xie

Lung cancer, a severe form of malignant tumor that originates in the tissues of the lungs, can be fatal if not detected in its early stages. It ranks among the top causes of cancer-related mortality worldwide. Detecting lung cancer manually…

Computer Vision and Pattern Recognition · Computer Science 2025-04-22 Santanu Roy , Shweta Singh , Palak Sahu , Ashvath Suresh , Debashish Das

Purpose: The lung nodules localization in CT scan images is the most difficult task due to the complexity of the arbitrariness of shape, size, and texture of lung nodules. This is a challenge to be faced when coming to developing different…

Image and Video Processing · Electrical Eng. & Systems 2023-01-06 Haytham Al Ewaidat , Youness El Brag

Lung cancer is the commonest cause of cancer deaths worldwide, and its mortality can be reduced significantly by performing early diagnosis and screening. Since the 1960s, driven by the pressing needs to accurately and effectively interpret…

Computer Vision and Pattern Recognition · Computer Science 2020-04-27 Bo Liu , Wenhao Chi , Xinran Li , Peng Li , Wenhua Liang , Haiping Liu , Wei Wang , Jianxing He

Background and Objective: Early detection of lung cancer is crucial as it has high mortality rate with patients commonly present with the disease at stage 3 and above. There are only relatively few methods that simultaneously detect and…

Image and Video Processing · Electrical Eng. & Systems 2020-12-18 Kelvin Shak , Mundher Al-Shabi , Andrea Liew , Boon Leong Lan , Wai Yee Chan , Kwan Hoong Ng , Maxine Tan

Accurate tumor staging in lung cancer is crucial for prognosis and treatment planning and is governed by explicit anatomical criteria under fixed guidelines. However, most existing deep learning approaches treat this spatially structured…

Computer Vision and Pattern Recognition · Computer Science 2026-04-23 Saniah Kayenat Chowdhury , Rusab Sarmun , Muhammad E. H. Chowdhury , Sohaib Bassam Zoghoul , Israa Al-Hashimi , Adam Mushtak , Amith Khandakar

Automated detection and segmentation of pulmonary nodules on lung computed tomography (CT) scans can facilitate early lung cancer diagnosis. Existing supervised approaches for automated nodule segmentation on CT scans require voxel-based…

Computer Vision and Pattern Recognition · Computer Science 2018-02-26 Xinyang Feng , Jie Yang , Andrew F. Laine , Elsa D. Angelini

Computed tomography imaging is a standard modality for detecting and assessing lung cancer. In order to evaluate the malignancy of lung nodules, clinical practice often involves expert qualitative ratings on several criteria describing a…

Computer Vision and Pattern Recognition · Computer Science 2016-09-22 Mario Buty , Ziyue Xu , Mingchen Gao , Ulas Bagci , Aaron Wu , Daniel J. Mollura