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Whole Slide Image (WSI) analysis plays a crucial role in modern digital pathology, enabling large-scale feature extraction from tissue samples. However, traditional feature extraction pipelines based on tools like CellProfiler often involve…

Image and Video Processing · Electrical Eng. & Systems 2025-01-13 Yuechen Yang , Yu Wang , Tianyuan Yao , Ruining Deng , Mengmeng Yin , Shilin Zhao , Haichun Yang , Yuankai Huo

The exchange of large and complex slide microscopy imaging data in biomedical research and pathology practice is impeded by a lack of data standardization and interoperability, which is detrimental to the reproducibility of scientific…

Physics and computer science have a long tradition of cross-fertilization. One of the latest outcomes of this mutually beneficial relationship is quantum information science, which comprises the study of information processing tasks that…

Quantum Physics · Physics 2020-06-17 Fei Yan , Salvador E. Venegas-Andraca , Kaoru Hirota

The microscopic examination of surgical tissue remains a cornerstone of disease classification but relies on subjective interpretations and access to highly specialized experts, which can compromise accuracy and clinical care. While…

To achieve minimum DNA input and tumor purity requirements for next-generation sequencing (NGS), pathologists visually estimate macrodissection and slide count decisions. Misestimation may cause tissue waste and increased laboratory costs.…

Statistical Parametric Mapping (SPM) is an integrated set of methods for testing hypotheses about the brain's structure and function, using data from imaging devices. These methods are implemented in an open source software package, SPM,…

We describe QWalk, a new computational package capable of performing Quantum Monte Carlo electronic structure calculations for molecules and solids with many electrons. We describe the structure of the program and its implementation of…

Computational Physics · Physics 2007-10-25 Lucas K. Wagner , Michal Bajdich , Lubos Mitas

This article reviews recent hybrid approaches to optical quantum information processing, in which both discrete and continuous degrees of freedom are exploited. There are well-known limitations to optical single-photon-based qubit and…

Quantum Physics · Physics 2010-02-26 Peter van Loock

This paper describes an ongoing multi-scale visual analytics approach for exploring and analyzing biomedical knowledge at scale.We utilize global and local views, hierarchical and flow-based graph layouts, multi-faceted search, neighborhood…

Human-Computer Interaction · Computer Science 2021-10-22 Fahd Husain , Rosa Romero-Gomez , Emily Kuang , Dario Segura , Adamo Carolli , Lai Chung Liu , Manfred Cheung , Yohann Paris

The qubit mapping problem is a challenge in quantum computing that is related to mapping logical qubits to the physical ones on the quantum computer. Due to the diversity of quantum computer topologies and circuits, numerous approaches…

Quantum Physics · Physics 2026-03-03 Gabrielius Keibas , Linas Petkevičius

Quasi Static Elasticity Imaging (QSEI) aims to computationally reconstruct the inhomogeneous distribution of the elastic modulus using a measured displacement field. QSEI is a well-established imaging modality used in medical imaging for…

Computational Physics · Physics 2018-02-27 Danny Smyl , Sven Bossuyt , Dong Liu

Recent studies have made significant progress in developing large language models (LLMs) in the medical domain, which can answer expert-level questions and demonstrate the potential to assist clinicians in real-world clinical scenarios.…

Computation and Language · Computer Science 2025-04-18 Sangwook Kim , Soonyoung Lee , Jongseong Jang

We introduce the MATLAB-based software QuITO (Quasi-Interpolation based Trajectory Optimization) to numerically solve a wide class of constrained nonlinear optimal control problems (OCP). The solver is based on the QuITO (the same…

Optimization and Control · Mathematics 2023-12-29 Siddhartha Ganguly , Nakul Randad , Rihan Aaron D'Silva , Mukesh S Raj , Debasish Chatterjee

Histopathological image analysis is an essential process for the discovery of diseases such as cancer. However, it is challenging to train CNN on whole slide images (WSIs) of gigapixel resolution considering the available memory capacity.…

Image and Video Processing · Electrical Eng. & Systems 2019-10-11 Shusuke Takahama , Yusuke Kurose , Yusuke Mukuta , Hiroyuki Abe , Masashi Fukayama , Akihiko Yoshizawa , Masanobu Kitagawa , Tatsuya Harada

Web browsers are increasingly used as middleware platforms offering a central access point for service provision. Using backend containerization, RESTful APIs, and distributed computing allows for complex systems to be realized that address…

Distributed, Parallel, and Cluster Computing · Computer Science 2017-10-03 Rudolph Pienaar , Ata Turk , Jorge Bernal-Rusiel , Nicolas Rannou , Daniel Haehn , P. Ellen Grant , Orran Krieger

OpenFMO framework, an open-source software (OSS) platform for Fragment Molecular Orbital (FMO) method, is extended to multi-physics simulations (MPS). After reviewing the several FMO implementations on distributed computer environments, the…

Distributed, Parallel, and Cluster Computing · Computer Science 2009-09-29 Toshiya Takami , Jun Maki , Jun'ichi Ooba , Yuuichi Inadomi , Hiroaki Honda , Ryutaro Susukita , Koji Inoue , Taizo Kobayashi , Rie Nogita , Mutsumi Aoyagi

The lack of flexible annotation tools has hindered the deployment of AI models in some scientific areas. Most existing image annotation software requires users to upload a precollected dataset, which limits support for on-demand pipelines…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Uriel Garcilazo-Cruz , Joseph O. Okeme , Rodrigo A. Vargas-Hernández

The histopathology analysis is of great significance for the diagnosis and prognosis of cancers, however, it has great challenges due to the enormous heterogeneity of gigapixel whole slide images (WSIs) and the intricate representation of…

Image and Video Processing · Electrical Eng. & Systems 2024-02-09 Mingxin Liu , Yunzan Liu , Pengbo Xu , Jiquan Ma

We describe 2DPHOT, a general purpose analysis environment for source detection and analysis in deep wide-field images. 2DPHOT is an automated tool to obtain both integrated and surface photometry of galaxies in an image, to perform…

We have designed and implemented a novel way to process wide-field astronomical data within a distributed environment of hardware resources and humanpower. The system is characterized by integration of archiving, calibration, and…

Instrumentation and Methods for Astrophysics · Physics 2011-10-17 J. P. McFarland , G. Verdoes-Kleijn , G. Sikkema , E. M. Helmich , D. R. Boxhoorn , E. A. Valentijn