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Systematic deflection of microparticles off of initial streamlines is a fundamental task in microfluidics, aiming at applications including sorting, accumulation, or capture of the transported particles. In a large class of setups,…

Fluid Dynamics · Physics 2026-04-01 Partha Kumar Das , Xuchen Liu , Sascha Hilgenfeldt

Manipulation of small-scale particles across streamlines is the elementary task of microfluidic devices. Many such devices operate at very low Reynolds numbers and deflect particles using arrays of obstacles, but a systematic quantification…

Fluid Dynamics · Physics 2025-03-19 Xuchen Liu , Partha Kumar Das , Sascha Hilgenfeldt

The main motivation of this work is the quantitative prediction and description of particle manipulation (displacement across streamlines) in microfluidic flow. Much attention has been paid recently to placing particles in fast oscillatory…

Fluid Dynamics · Physics 2026-03-24 Xuchen Liu

We use a macromodel of a flow-driven deterministic lateral displacement (DLD) microfluidic system to investigate conditions leading to size-separation of suspended particles. This model system can be easily reconfigured to establish an…

Fluid Dynamics · Physics 2016-04-27 Siqi Du , German Drazer

We investigate both experimentally and theoretically the traffic of particles flowing in microfluidic obstacle networks. We show that the traffic dynamics is a non-linear process: the particle current does not scale with the particle…

Statistical Mechanics · Physics 2015-05-19 Nicolas Champagne , Romain Vasseur , Adrien Montourcy , Denis Bartolo

The ability to separate and analyze chemical species with high resolution, sensitivity, and throughput is central to the development of microfluidics systems. Deterministic lateral displacement (DLD) is a continuous separation method based…

Fluid Dynamics · Physics 2014-04-15 Timothy J. Bowman , German Drazer , Joelle Frechette

The manipulation and control of microparticles through non-intrusive methods is pivotal in biomedical applications such as cell sorting and cell focusing. Although several experimental and numerical studies have been dedicated to single…

Fluid Dynamics · Physics 2023-12-20 Giancarlo Esposito , Gaetano D'Avino , Massimiliano Maria Villone

A flowing pair of particles in inertial microfluidics gives important insights into understanding and controlling the collective dynamics of particles like cells or droplets in microfluidic devices. They are applied in medical cell analysis…

Fluid Dynamics · Physics 2018-05-25 Christian Schaaf , Felix Rühle , Holger Stark

The identification of cells and particles based on their transport properties in microfluidic devices is crucial for numerous applications in biology and medicine. Neutrally buoyant particles transported in microfluidic channels, migrate…

In this paper, we describe the unification and extension of multiple kinematic theories on the advection of colloidal particles through periodic obstacle lattices of arbitrary geometry and infinitesimally small obstacle size. We focus…

Computational Physics · Physics 2020-03-25 Arnaldo Rodriguez-Gonzalez , Jason P. Gleghorn , Brian J. Kirby

Transport phenomena in complex and dynamic microscopic environments are fundamentally shaped by hydrodynamic interactions. In particular, microparticle transport in porous media is governed by the delicate interplay between…

A colloidal particle driven by externally actuated rotation can self-propel parallel to a rigid boundary by exploiting the hydrodynamic coupling that surfaces induce between translation and rotation. As such a roller moves along the…

Fluid Dynamics · Physics 2020-02-20 Alexander Chamolly , Eric Lauga , Soichiro Tottori

Inertial lift forces are exploited within inertial microfluidic devices to position, segregate, and sort particles or droplets. However the forces and their focusing positions can currently only be predicted by numerical simulations, making…

Fluid Dynamics · Physics 2016-07-21 Kaitlyn Hood , Sungyon Lee , Marcus Roper

An electrokinetically-driven deterministic lateral displacement (e-DLD) device is proposed for the continuous, two-dimensional fractionation of suspensions in microfluidic platforms. The suspended species are driven through an array of…

Fluid Dynamics · Physics 2016-05-04 Srinivas Hanasoge , Raghavendra Devendra , Javier F. Diez , German Drazer

In inertial microfluidics lift forces cause a particle to migrate across streamlines to specific positions in the cross section of a microchannel. We control the rotational motion of a particle and demonstrate that this allows to manipulate…

Fluid Dynamics · Physics 2014-02-11 Christopher Prohm , Nikolas Zöller , Holger Stark

Within microcentrifuge devices, a microfluidic vortex separates larger particles from a heterogeneous suspension using inertial migration, a phenomenon that causes particles to migrate across streamlines. The ability to selectively capture…

Fluid Dynamics · Physics 2023-03-14 Samuel Christensen , Marcus Roper

The capture of a soft spherical particle by a rectangular slit leads to a non-monotonic pressure-flow rate relation at low Reynolds number. In the presence of the trapped particle the flow-induced deformations focus the streamlines and…

Soft Condensed Matter · Physics 2023-02-22 Charles Paul Moore , Julien Husson , Arezki Boudaoud , Gabriel Amselem , Charles N. Baroud

The controllability of passive microparticles that are advected with the fluid flow generated by an actively controlled one is studied. The particles are assumed to be suspended in a viscous fluid and well separated so that the far-field…

Fluid Dynamics · Physics 2025-02-05 Henry Shum , Marta Zoppello , Michael Astwood , Marco Morandotti

Deterministic lateral displacement (DLD) microfluidic devices promise versatile and precise processing of biological samples. However, this prospect has been realized so far only for rigid spherical particles and remains limited for…

Soft Condensed Matter · Physics 2024-06-03 Wei Chien , Zunmin Zhang , Gerhard Gompper , Dmitry A. Fedosov

We study colloidal particles in a nematic-liquid-crystal-filled microfluidic channel and show how elastic interactions between the particle and the channel wall lead to different particle dynamics compared with conventional microfluidics.…

Soft Condensed Matter · Physics 2017-07-31 Sourav Mondal , Apala Majumdar , Ian M. Griffiths
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