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Recent advances in generative AI have accelerated the discovery of novel chemicals and materials. However, scaling these discoveries to industrial production remains a major bottleneck due to the synthesis gap -- the need to develop…

Machine Learning · Computer Science 2025-08-19 Sakhinana Sagar Srinivas , Shivam Gupta , Venkataramana Runkana

Scientific Deep Research (DR) agents answer user queries by synthesizing research papers into multi-section reports. User feedback can improve their utility, but existing protocols only score the final report, making it hard to study and…

In the field of Human-Computer Interaction (HCI), interactive devices with embedded mechanical computation are gaining attention. The rise of these cutting-edge devices has created a need for specialized design tools that democratize the…

Human-Computer Interaction · Computer Science 2024-10-31 Qiuyu Lu , Jiawei Fang , Zhihao Yao , Yue Yang , Shiqing Lyu , Haipeng Mi , Lining Yao

Building on the conceptual framework presented in our previous work on agentic AI for pharmaceutical research, this paper provides a comprehensive technical analysis of Tippy's multi-agent system implementation for drug discovery laboratory…

Large Language Model (LLM) agents are increasingly applied to engineering design tasks, yet existing evaluation frameworks do not adequately address multi-agent systems that combine simulation, retrieval, and manufacturing preparation. We…

Artificial Intelligence · Computer Science 2026-05-28 Gioele Molinari , Florian Felten , Soheyl Massoudi , Mark Fuge

Malicious code in open-source repositories such as PyPI poses a growing threat to software supply chains. Traditional rule-based tools often overlook the semantic patterns in source code that are crucial for identifying adversarial…

Software Engineering · Computer Science 2026-01-27 Muhammad Umar Zeshan , Motunrayo Ibiyo , Claudio Di Sipio , Phuong T. Nguyen , Davide Di Ruscio

Modern software engineers operate across 5-10 disconnected tools daily: GitHub, GitLab, Jira, Slack, calendar applications, CI dashboards, AI coding assistants, and container platforms. This fragmentation creates cognitive overhead that…

Software Engineering · Computer Science 2026-04-21 Happy Bhati

In the rapidly evolving field of Electronic Design Automation (EDA), the deployment of Large Language Models (LLMs) for Register-Transfer Level (RTL) design has emerged as a promising direction. However, silicon-grade correctness remains…

Hardware Architecture · Computer Science 2026-01-28 Jiale Liu , Taiyu Zhou , Tianqi Jiang

The increasing presence of large-scale distributed systems highlights the need for scalable control strategies where only local communication is required. Moreover, in safety-critical systems it is imperative that such control strategies…

Optimization and Control · Mathematics 2022-03-16 Carmen Amo Alonso , Jing Shuang Li , James Anderson , Nikolai Matni

Discrete Choice Experiments (DCEs) are widely used to elicit preferences for products or services by analyzing choices among alternatives described by their attributes. The quality of the insights obtained from a DCE heavily depends on the…

Econometrics · Economics 2026-03-23 Daniel Pérez-Troncoso

Many modern embedded systems have end-to-end (EtoE) latency constraints that necessitate precise timing to ensure high reliability and functional correctness. The combination of High-Level Synthesis (HLS) and Design Space Exploration (DSE)…

Hardware Architecture · Computer Science 2024-09-26 Yuchao Liao , Tosiron Adegbija , Roman Lysecky

The continuously increasing degree of automation in many areas (e.g. manufacturing engineering, public infrastructure) lead to the construction of cyber-physical systems and cyber-physical networks. To both, time and energy are the most…

Networking and Internet Architecture · Computer Science 2019-05-29 Stefan Reif , Andreas Schmidt , Timo Hönig , Thorsten Herfet , Wolfgang Schröder-Preikschat

Agentic systems augment large language models with external tools and iterative decision making, enabling complex tasks such as deep research, function calling, and coding. However, their long and intricate execution traces make failure…

Multi-agent LLM systems fail in production at rates between 41% and 87%, mostly due to coordination defects rather than base-model capability. Existing responses split between cataloguing failure modes empirically and shipping declarative…

Multiagent Systems · Computer Science 2026-05-06 Maksym Nechepurenko , Pavel Shuvalov

Agentic AI marks an important transition from single-step generative models to systems capable of reasoning, planning, acting, and adapting over long-lasting tasks. By integrating memory, tool use, and iterative decision cycles, these…

Cryptography and Security · Computer Science 2026-01-12 Sahaya Jestus Lazer , Kshitiz Aryal , Maanak Gupta , Elisa Bertino

Resistive crossbars enabling analog In-Memory Computing (IMC) have emerged as a promising architecture for Deep Neural Network (DNN) acceleration, offering high memory bandwidth and in-situ computation. However, the manual,…

Hardware Architecture · Computer Science 2025-03-18 Deepak Vungarala , Md Hasibul Amin , Pietro Mercati , Arnob Ghosh , Arman Roohi , Ramtin Zand , Shaahin Angizi

Although fabrication capabilities of Silicon Dangling Bonds have rapidly advanced from manual labor-driven laboratory work to automated manufacturing in just recent years, sub-nanometer substrate defects still pose a hindrance to production…

This paper presents CRADLE, a conversational framework for design space exploration of RTL designs using LLM-based multi-agent systems. Unlike existing rigid approaches, CRADLE enables user-guided flows with internal self-verification,…

Robotics · Computer Science 2025-08-13 Lukas Krupp , Maximilian Schöffel , Elias Biehl , Norbert Wehn

As large language models are integrated into autonomous robotic systems for task planning and control, compromised inputs or unsafe model outputs can propagate through the planning pipeline to physical-world consequences. Although prior…

Cryptography and Security · Computer Science 2026-05-05 Neha Nagaraja , Hayretdin Bahsi , Carlo R. da Cunha

Large Language Model (LLM)-based agents are increasingly employed to automate complex software engineering tasks, such as program repair and issue resolution. These agents operate by autonomously generating natural language thoughts,…

Software Engineering · Computer Science 2025-10-09 Islem Bouzenia , Michael Pradel
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