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Related papers: Tokenization Tradeoffs in Structured EHR Foundatio…

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Objectives: Electronic health records (EHRs) are only a first step in capturing and utilizing health-related data - the challenge is turning that data into useful information. Furthermore, EHRs are increasingly likely to include data…

Artificial Intelligence · Computer Science 2012-08-20 Casey Bennett , Tom Doub , Rebecca Selove

Clinical language models have achieved strong performance on downstream tasks by pretraining on domain specific corpora such as discharge summaries and medical notes. However, most approaches treat the electronic health record as a static…

Computation and Language · Computer Science 2025-04-28 Tatsunori Tanaka , Fi Zheng , Kai Sato , Zhifeng Li , Yuanyun Zhang , Shi Li

This study proposes a Transformer-based longitudinal modeling method to address challenges in clinical risk classification with heterogeneous Electronic Health Record (EHR) data, including irregular temporal patterns, large modality…

Machine Learning · Computer Science 2025-11-07 Anzhuo Xie , Wei-Chen Chang

Structured electronic health records (EHR) are essential for clinical prediction. While count-based learners continue to perform strongly on such data, no benchmarking has directly compared them against more recent mixture-of-agents LLM…

Artificial Intelligence · Computer Science 2025-11-04 Jifan Gao , Michael Rosenthal , Brian Wolpin , Simona Cristea

The widespread adoption of electronic health records (EHRs) enables the acquisition of heterogeneous clinical data, spanning lab tests, vital signs, medications, and procedures, which offer transformative potential for artificial…

Signal Processing · Electrical Eng. & Systems 2026-03-17 Mingcheng Zhu , Yu Liu , Zhiyao Luo , Tingting Zhu

Electronic health records (EHRs) are longitudinal records of a patient's interactions with healthcare systems. A patient's EHR data is organized as a three-level hierarchy from top to bottom: patient journey - all the experiences of…

Machine Learning · Computer Science 2020-09-29 Xueping Peng , Guodong Long , Tao Shen , Sen Wang , Jing Jiang , Chengqi Zhang

Deep learning-based predictive models, leveraging Electronic Health Records (EHR), are receiving increasing attention in healthcare. An effective representation of a patient's EHR should hierarchically encompass both the temporal…

Machine Learning · Computer Science 2024-05-08 Jiayuan Chen , Changchang Yin , Yuanlong Wang , Ping Zhang

Foundation models trained on patient electronic health records (EHRs) require tokenizing medical data into sequences of discrete vocabulary items. Existing tokenizers treat medical codes from EHRs as isolated textual tokens. However, each…

Computation and Language · Computer Science 2025-07-01 Xiaorui Su , Shvat Messica , Yepeng Huang , Ruth Johnson , Lukas Fesser , Shanghua Gao , Faryad Sahneh , Marinka Zitnik

Token representations in high-dimensional latent spaces often exhibit redundancy, limiting computational efficiency and reducing structural coherence across model layers. Hierarchical latent space folding introduces a structured…

Computation and Language · Computer Science 2025-08-11 Fenella Harcourt , Naderdel Piero , Gilbert Sutherland , Daphne Holloway , Harriet Bracknell , Julian Ormsby

While large-scale pretraining has revolutionized language modeling, its potential remains underexplored in healthcare with structured electronic health records (EHRs). We present RAVEN, a novel generative pretraining strategy for sequential…

We investigate the impact of tokeniser pretraining on the accuracy and efficiency of physics emulation. Modern high-resolution simulations produce vast volumes of data spanning diverse physical regimes and scales. Training foundation models…

Machine Learning · Computer Science 2026-03-13 Hadi Sotoudeh , Payel Mukhopadhyay , Ruben Ohana , Michael McCabe , Neil D. Lawrence , Shirley Ho , Miles Cranmer

The widespread application of Electronic Health Records (EHR) data in the medical field has led to early successes in disease risk prediction using deep learning methods. These methods typically require extensive data for training due to…

Machine Learning · Computer Science 2024-11-28 Shibo Li , Hengliang Cheng , Weihua Li

Tokenization is an understudied and often neglected component of modern LLMs. Most published works use a single tokenizer for all experiments, often borrowed from another model, without performing ablations or analysis to optimize…

Computation and Language · Computer Science 2024-02-08 Gautier Dagan , Gabriel Synnaeve , Baptiste Rozière

Effective modeling of electronic health records (EHR) is rapidly becoming an important topic in both academia and industry. A recent study showed that using the graphical structure underlying EHR data (e.g. relationship between diagnoses…

Machine Learning · Computer Science 2020-01-22 Edward Choi , Zhen Xu , Yujia Li , Michael W. Dusenberry , Gerardo Flores , Yuan Xue , Andrew M. Dai

Electronic Health Record (EHR) data can be represented as discrete counts over a high dimensional set of possible procedures, diagnoses, and medications. Supervised topic models present an attractive option for incorporating EHR data as…

Machine Learning · Computer Science 2019-11-21 Jason Ren , Russell Kunes , Finale Doshi-Velez

Electronic Health Records (EHRs) contain rich patient information and are crucial for clinical research and practice. In recent years, deep learning models have been applied to EHRs, but they often rely on massive features, which may not be…

Machine Learning · Computer Science 2024-06-11 Ran Xu , Yiwen Lu , Chang Liu , Yong Chen , Yan Sun , Xiao Hu , Joyce C Ho , Carl Yang

Electronic Health Records (EHRs) contain rich temporal dynamics that conventional encoding approaches fail to adequately capture. While Large Language Models (LLMs) show promise for EHR modeling, they struggle to reason about sequential…

Artificial Intelligence · Computer Science 2025-10-01 Zekai Chen , Arda Pekis , Kevin Brown

The wide adoption of Electronic Health Records (EHR) has resulted in large amounts of clinical data becoming available, which promises to support service delivery and advance clinical and informatics research. Deep learning techniques have…

Machine Learning · Computer Science 2022-02-14 Thanh Nguyen-Duc , Natasha Mulligan , Gurdeep S. Mannu , Joao H. Bettencourt-Silva

The modelling of Electronic Health Records (EHRs) has the potential to drive more efficient allocation of healthcare resources, enabling early intervention strategies and advancing personalised healthcare. However, EHRs are challenging to…

Machine Learning · Computer Science 2020-12-08 Joseph Enguehard , Dan Busbridge , Adam Bozson , Claire Woodcock , Nils Y. Hammerla

Electronic Health Records (EHRs) contain rich, longitudinal patient information across structured (e.g., labs, vitals, and imaging) and unstructured (e.g., clinical notes) modalities. While deep learning models such as RNNs and Transformers…

Machine Learning · Computer Science 2026-02-18 Mohammad Al Olaimat , Shaika Chowdhury , Serdar Bozdag