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The availability of large-scale chest X-ray datasets is a requirement for developing well-performing deep learning-based algorithms in thoracic abnormality detection and classification. However, biometric identifiers in chest radiographs…

Image and Video Processing · Electrical Eng. & Systems 2024-10-28 Kai Packhäuser , Lukas Folle , Florian Thamm , Andreas Maier

Recent advances in synthetic imaging open up opportunities for obtaining additional data in the field of surgical imaging. This data can provide reliable supplements supporting surgical applications and decision-making through computer…

Image and Video Processing · Electrical Eng. & Systems 2023-12-07 Simeon Allmendinger , Patrick Hemmer , Moritz Queisner , Igor Sauer , Leopold Müller , Johannes Jakubik , Michael Vössing , Niklas Kühl

Generative AI models hold great potential in creating synthetic brain MRIs that advance neuroimaging studies by, for example, enriching data diversity. However, the mainstay of AI research only focuses on optimizing the visual quality (such…

Image and Video Processing · Electrical Eng. & Systems 2023-10-10 Wei Peng , Tomas Bosschieter , Jiahong Ouyang , Robert Paul , Ehsan Adeli , Qingyu Zhao , Kilian M. Pohl

Locating lesions is important in the computer-aided diagnosis of X-ray images. However, box-level annotation is time-consuming and laborious. How to locate lesions accurately with few, or even without careful annotations is an urgent…

Computer Vision and Pattern Recognition · Computer Science 2021-02-02 Gangming Zhao , Baolian Qi , Jinpeng Li

Counterfactual generation offers a principled framework for simulating hypothetical changes in medical imaging, with potential applications in understanding disease mechanisms and generating physiologically plausible data. However,…

Image and Video Processing · Electrical Eng. & Systems 2025-08-25 Pengwei Sun , Wei Peng , Lun Yu Li , Yixin Wang , Kilian M. Pohl

Histopathology image classification is crucial for the accurate identification and diagnosis of various diseases but requires large and diverse datasets. Obtaining such datasets, however, is often costly and time-consuming due to the need…

Computer Vision and Pattern Recognition · Computer Science 2024-09-25 Leire Benito-Del-Valle , Aitor Alvarez-Gila , Itziar Eguskiza , Cristina L. Saratxaga

Deep generative models and synthetic medical data have shown significant promise in addressing key challenges in healthcare, such as privacy concerns, data bias, and the scarcity of realistic datasets. While research in this area has grown…

Machine Learning · Computer Science 2025-02-05 Krishan Agyakari Raja Babu , Supriti Mulay , Om Prabhu , Mohanasankar Sivaprakasam

Generative adversarial networks have been successfully applied to inpainting in natural images. However, the current state-of-the-art models have not yet been widely adopted in the medical imaging domain. In this paper, we investigate the…

Graphics · Computer Science 2018-09-06 Ecem Sogancioglu , Shi Hu , Davide Belli , Bram van Ginneken

Chest X-rays are widely used to diagnose thoracic diseases, but the lack of detailed information about these abnormalities makes it challenging to develop accurate automated diagnosis systems, which is crucial for early detection and…

Computer Vision and Pattern Recognition · Computer Science 2024-05-24 S. M. Nabil Ashraf , Md. Adyelullahil Mamun , Hasnat Md. Abdullah , Md. Golam Rabiul Alam

Clinical systems operate in safety-critical environments and are not intended to function autonomously; however, they are currently designed to replicate clinicians' diagnoses rather than assist them in the diagnostic process. To enable…

Human-Computer Interaction · Computer Science 2025-04-07 Kailas Dayanandan , Brejesh Lall

The synthesis of high-quality 3D assets from textual or visual inputs has become a central objective in modern generative modeling. Despite the proliferation of 3D generation algorithms, they frequently grapple with challenges such as…

Computer Vision and Pattern Recognition · Computer Science 2025-01-17 Hwan Heo , Jangyeong Kim , Seongyeong Lee , Jeong A Wi , Junyoung Choi , Sangjun Ahn

Generative models capable of capturing nuanced clinical features in medical images hold great promise for facilitating clinical data sharing, enhancing rare disease datasets, and efficiently synthesizing annotated medical images at scale.…

Image and Video Processing · Electrical Eng. & Systems 2023-06-23 Shenghuan Sun , Gregory M. Goldgof , Atul Butte , Ahmed M. Alaa

In clinical applications, the utility of segmentation models is often based on the accuracy of derived downstream metrics such as organ size, rather than by the pixel-level accuracy of the segmentation masks themselves. Thus, uncertainty…

Image and Video Processing · Electrical Eng. & Systems 2026-03-03 Matt Y. Cheung , Ashok Veeraraghavan , Guha Balakrishnan

Recently, chest X-ray report generation, which aims to automatically generate descriptions of given chest X-ray images, has received growing research interests. The key challenge of chest X-ray report generation is to accurately capture and…

Computer Vision and Pattern Recognition · Computer Science 2023-04-12 Fenglin Liu , Changchang Yin , Xian Wu , Shen Ge , Yuexian Zou , Ping Zhang , Yuexian Zou , Xu Sun

Perturbation-based explainability methods such as KernelSHAP provide model-agnostic attributions but are typically impractical for patch-based 3D medical image segmentation due to the large number of coalition evaluations and the high cost…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Ricardo Coimbra Brioso , Giulio Sichili , Damiano Dei , Nicola Lambri , Pietro Mancosu , Marta Scorsetti , Daniele Loiacono

Foundation diffusion models can generate photorealistic natural images, but adapting them to medical imaging remains challenging. In medical adaptation, limited labeled data can exacerbate hallucination-like and clinically implausible…

Computer Vision and Pattern Recognition · Computer Science 2026-05-14 Yunsung Chung , Alex El Darzi , Carlo El Khoury , Han Feng , Nassir Marrouche , Jihun Hamm

Advancements in generative Artificial Intelligence (AI) hold great promise for automating radiology workflows, yet challenges in interpretability and reliability hinder clinical adoption. This paper presents an automated radiology report…

Supervised training of an automated medical image analysis system often requires a large amount of expert annotations that are hard to collect. Moreover, the proportions of data available across different classes may be highly imbalanced…

Computer Vision and Pattern Recognition · Computer Science 2019-12-10 Yuan Xue , Jiarong Ye , Rodney Long , Sameer Antani , Zhiyun Xue , Xiaolei Huang

Multimodal medical image fusion integrates complementary information from different imaging modalities to enhance diagnostic accuracy and treatment planning. While deep learning methods have advanced performance, existing approaches face…

Image and Video Processing · Electrical Eng. & Systems 2025-08-06 Meng Zhou , Farzad Khalvati

Chimeric antigen receptor (CAR)-T and NK cell immunotherapies have transformed cancer treatment, and recent studies suggest that the quality of the CAR-T/NK cell immunological synapse (IS) may serve as a functional biomarker for predicting…

Computer Vision and Pattern Recognition · Computer Science 2026-02-04 Xiang Zhang , Boxuan Zhang , Alireza Naghizadeh , Mohab Mohamed , Dongfang Liu , Ruixiang Tang , Dimitris Metaxas , Dongfang Liu