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Motivation The Burrows-Wheeler transform (BWT) is the foundation of many algorithms for compression and indexing of text data, but the cost of computing the BWT of very large string collections has prevented these techniques from being…

Data Structures and Algorithms · Computer Science 2015-03-20 Anthony J. Cox , Markus J. Bauer , Tobias Jakobi , Giovanna Rosone

Motivation: Despite significant advances in Third-Generation Sequencing (TGS) technologies, Next-Generation Sequencing (NGS) technologies remain dominant in the current sequencing market. This is due to the lower error rates and richer…

Information Theory · Computer Science 2023-04-04 Jia Wang , Yi Niu , Tianyi Xu , Mingming Ma , Dahua Gao , Guangming Shi

DNA sequencing technology has advanced to a point where storage is becoming the central bottleneck in the acquisition and mining of more data. Large amounts of data are vital for genomics research, and generic compression tools, while…

Information Theory · Computer Science 2016-11-15 Bobbie Chern , Idoia Ochoa , Alexandros Manolakos , Albert No , Kartik Venkat , Tsachy Weissman

Current methods which compress multisets at an optimal rate have computational complexity that scales linearly with alphabet size, making them too slow to be practical in many real-world settings. We show how to convert a compression…

Information Theory · Computer Science 2023-02-28 Daniel Severo , James Townsend , Ashish Khisti , Alireza Makhzani , Karen Ullrich

For the last few decades, the application of signal-adaptive transform coding to video compression has been stymied by the large computational complexity of matrix-based solutions. In this paper, we propose a novel parametric approach to…

Image and Video Processing · Electrical Eng. & Systems 2025-05-29 Amir Said , Xin Zhao , Marta Karczewicz , Hilmi E. Egilmez , Vadim Seregin , Jianle Chen

The enhanced Deep Hierarchical Video Compression-DHVC 2.0-has been introduced. This single-model neural video codec operates across a broad range of bitrates, delivering not only superior compression performance to representative methods…

Image and Video Processing · Electrical Eng. & Systems 2024-10-04 Ming Lu , Zhihao Duan , Wuyang Cong , Dandan Ding , Fengqing Zhu , Zhan Ma

Fully Homomorphic Encryption (FHE) enables computation directly on encrypted data but incurs massive computational and memory overheads, often exceeding plaintext execution by several orders of magnitude. While custom ASIC accelerators can…

Composite DNA is a recent novel method to increase the information capacity of DNA-based data storage above the theoretical limit of 2 bits/symbol. In this method, every composite symbol does not store a single DNA nucleotide but a mixture…

Information Theory · Computer Science 2025-01-22 Tuan Thanh Nguyen , Chen Wang , Kui Cai , Yiwei Zhang , Zohar Yakhini

We introduce HiCat (Hybrid Cell Annotation using Transformative embeddings), a novel semi-supervised pipeline for annotating cell types from single-cell RNA sequencing data. HiCat fuses the strengths of supervised learning for known cell…

Biomolecules · Quantitative Biology 2025-08-21 Chang Bi , Kailun Bai , Xing Li , Xuekui Zhang

Genome sequence analysis, which examines the DNA sequences of organisms, drives advances in many critical medical and biotechnological fields. Given its importance and the exponentially growing volumes of genomic sequence data, there are…

With the rapid evolution of autonomous driving technology and intelligent transportation systems, semantic segmentation has become increasingly critical. Precise interpretation and analysis of real-world environments are indispensable for…

Image and Video Processing · Electrical Eng. & Systems 2025-05-29 Zhiyuan Li , Yi Chang , Yuan Wu

Recently, more and more images are compressed and sent to the back-end devices for the machine analysis tasks~(\textit{e.g.,} object detection) instead of being purely watched by humans. However, most traditional or learned image codecs are…

Image and Video Processing · Electrical Eng. & Systems 2022-06-14 Guo Lu , Xingtong Ge , Tianxiong Zhong , Jing Geng , Qiang Hu

Many previous works in spike sorting study spike classification and compression independently. In this paper, a novel algorithm is proposed called MetaSort to address these two problems. To deal with compression, a novel adaptive level…

Signal Processing · Electrical Eng. & Systems 2026-03-10 Luca M. Meyer , Majid Zamani

Predictive coding is attractive for compression onboard of spacecrafts thanks to its low computational complexity, modest memory requirements and the ability to accurately control quality on a pixel-by-pixel basis. Traditionally, predictive…

Information Theory · Computer Science 2014-01-15 Diego Valsesia , Enrico Magli

Audio coding is an essential module in the real-time communication system. Neural audio codecs can compress audio samples with a low bitrate due to the strong modeling and generative capabilities of deep neural networks. To address the poor…

Sound · Computer Science 2023-10-18 Wenzhe Liu , Wei Xiao , Meng Wang , Shan Yang , Yupeng Shi , Yuyong Kang , Dan Su , Shidong Shang , Dong Yu

This paper presents Bancroft, a computational genomics acceleration platform that provides the illusion of practically infinite on-device memory capacity by compressing genomic data movement over PCIe. Bancroft introduces novel…

Hardware Architecture · Computer Science 2025-02-25 Se-Min Lim , Seongyoung Kang , Sang-Woo Jun

The rapid growth of digital data has heightened the demand for efficient lossless compression methods. However, existing algorithms exhibit trade-offs: some achieve high compression ratios, others excel in encoding or decoding speed, and…

Information Theory · Computer Science 2025-10-01 Md. Atiqur Rahman , MM Fazle Rabbi

In the modern era, large volumes of data are being produced continuously, especially in domain-specific fields such as medical records and clinical files, defence logs and HTML-based web traffic. Data with such volume and complexity needs…

Information Retrieval · Computer Science 2025-08-21 Anurag Kumar Ojha

Discrete speech tokenization is a fundamental component in speech codecs. However, in large-scale speech-to-speech systems, the complexity of parallel streams from multiple quantizers and the computational cost of high-time-dimensional…

Sound · Computer Science 2025-07-28 Rongkun Xue , Yazhe Niu , Shuai Hu , Zixin Yin , Yongqiang Yao , Jing Yang

The quadratic cost of attention in transformers motivated the development of efficient approaches: namely sparse and sliding window attention, convolutions and linear attention. Although these approaches result in impressive reductions in…

Machine Learning · Computer Science 2025-11-10 Jatin Prakash , Aahlad Puli , Rajesh Ranganath