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A central feature of complex systems is the relevance and entanglement of different levels of description. For instance, the dynamics of ecosystems can be alternatively described in terms of large ecological processes and classes of…

Populations and Evolution · Quantitative Biology 2025-10-06 Juan Giral Martínez , Silvia de Monte , Matthieu Barbier

Complex systems are often characterized by the interplay of multiple interconnected dynamical processes operating across a range of temporal scales. This phenomenon is widespread in both biological and artificial scenarios, making it…

Statistical Mechanics · Physics 2025-09-08 Giorgio Nicoletti , Daniel M. Busiello

Species subject to predation and environmental threats commonly exhibit variable periods of population boom and bust over long timescales. Understanding and predicting such behavior, especially given the inherent heterogeneity and…

Populations and Evolution · Quantitative Biology 2024-06-03 Daniel Messenger , Greg Dwyer , Vanja Dukic

Diffusion models have demonstrated remarkable performance in generating high-dimensional samples across domains such as vision, language, and the sciences. Although continuous-state diffusion models have been extensively studied both…

Machine Learning · Computer Science 2026-02-17 Aadithya Srikanth , Mudit Gaur , Vaneet Aggarwal

In this paper we present a new modelling framework combining replicator dynamics (which is the standard model of frequency dependent selection) with the model of an age-structured population. The new framework allows for the modelling of…

Populations and Evolution · Quantitative Biology 2021-04-01 Krzysztof Argasinski , Mark Broom

We show that the semi-implicit time discretization approaches previously introduced for multilayer shallow water models for the barotropic case can be also applied to the variable density case with Boussinesq approximation. Furthermore,…

Numerical Analysis · Mathematics 2021-04-27 Luca Bonaventura , José Garres-Díaz

One of the aims of systems biology is to build multiple layered and multiple scale models of living systems which can efficiently describe phenomena occurring at various level of resolution. Such models should consist of layers of various…

Dynamical Systems · Mathematics 2015-03-03 Jacek Banasiak , Aleksandra Falkiewicz , Proscovia Namayanja

Multiscale modeling of complex systems is crucial for understanding their intricacies. Data-driven multiscale modeling has emerged as a promising approach to tackle challenges associated with complex systems. On the other hand,…

Machine Learning · Computer Science 2024-03-26 Ruyi Tao , Ningning Tao , Yi-zhuang You , Jiang Zhang

Although tissues are usually studied in isolation, this situation rarely occurs in biology, as cells, tissues, and organs, coexist and interact across scales to determine both shape and function. Here, we take a quantitative approach…

Tissues and Organs · Quantitative Biology 2023-02-07 Carles Falcó , Daniel J. Cohen , José A. Carrillo , Ruth E. Baker

The logistic equation is ubiquitous in applied mathematics as a minimal model of saturating growth. Here, we examine a broad generalisation of the logistic growth model to discretely structured populations, motivated by examples that range…

Populations and Evolution · Quantitative Biology 2025-05-15 Benjamin J. Walker , Helen M. Byrne

We perform the discrete-to-continuum limit passage for a microscopic model describing the time evolution of dislocations in a one dimensional setting. This answers the related open question raised by Geers et al. in [GPPS13]. The proof of…

Analysis of PDEs · Mathematics 2014-11-05 Patrick van Meurs , Adrian Muntean

Multistate dynamical processes on networks, where nodes can occupy one of a multitude of discrete states, are gaining widespread use because of their ability to recreate realistic, complex behaviour that cannot be adequately captured by…

Physics and Society · Physics 2017-09-29 Peter G. Fennell , James P. Gleeson

In a complex system, the individual components are neither so tightly coupled or correlated that they can all be treated as a single unit, nor so uncorrelated that they can be approximated as independent entities. Instead, patterns of…

Populations and Evolution · Quantitative Biology 2015-09-15 Blake C. Stacey

We analyze multivariate ordered discrete response models with a lattice structure, modeling decision makers who narrowly bracket choices across multiple dimensions. These models map latent continuous processes into discrete responses using…

Econometrics · Economics 2025-11-06 Tatiana Komarova , William Matcham

We develop a mesoscopic modeling framework for diffusion in a crowded environment, particularly targeting applications in the modeling of living cells. Through homogenization techniques we effectively coarse-grain a detailed microscopic…

Subcellular Processes · Quantitative Biology 2018-09-19 Stefan Engblom , Per Lötstedt , Lina Meinecke

This study presents a generalized multiscale nonlocal elasticity theory that leverages distributed order fractional calculus to accurately capture coexisting multiscale and nonlocal effects within a macroscopic continuum. The nonlocal…

Computational Engineering, Finance, and Science · Computer Science 2022-01-05 Wei Ding , Sansit Patnaik , Fabio Semperlotti

Time-evolving perforated domains arise in many engineering and geoscientific applications, including reactive transport, particle deposition, and structural degradation in porous media. Accurately capturing the macroscopic behavior of such…

Numerical Analysis · Mathematics 2025-06-27 Wei Xie , Viet Ha Hoang , Yin Yang , Yunqing Huang

In this paper we investigate the use of staged tree models for discrete longitudinal data. Staged trees are a type of probabilistic graphical model for finite sample space processes. They are a natural fit for longitudinal data because a…

Methodology · Statistics 2024-01-10 Jack Storror Carter , Manuele Leonelli , Eva Riccomagno , Alessandro Ugolini

Large language models are increasingly used to represent human opinions, values, or beliefs, and their steerability towards these ideals is an active area of research. Existing work focuses predominantly on aligning marginal response…

Computation and Language · Computer Science 2026-04-22 Tristan Williams , Franziska Weeber , Sebastian Padó , Alan Akbik

Different cell types aggregate and sort into hierarchical architectures during the formation of animal tissues. The resulting spatial organization depends (in part) on the strength of adhesion of one cell type to itself relative to other…

Quantitative Methods · Quantitative Biology 2023-08-02 Dhananjay Bhaskar , William Y. Zhang , Alexandria Volkening , Björn Sandstede , Ian Y. Wong
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