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Related papers: Open Biomedical Knowledge Graphs at Scale: Constru…

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We introduce CoDe-KG, an open-source, end-to-end pipeline for extracting sentence-level knowledge graphs by combining robust coreference resolution with syntactic sentence decomposition. Using our model, we contribute a dataset of over…

Computation and Language · Computer Science 2025-11-13 Sydney Anuyah , Mehedi Mahmud Kaushik , Krishna Dwarampudi , Rakesh Shiradkar , Arjan Durresi , Sunandan Chakraborty

Modern data architectures are fragmented across graph databases, vector stores, analytics engines, and optimization solvers, resulting in complex ETL pipelines and synchronization overhead. We present Samyama, a high-performance…

Databases · Computer Science 2026-03-11 Madhulatha Mandarapu , Sandeep Kunkunuru

Pharmacokinetic natural product-drug interactions (NPDIs) occur when botanical natural products are co-consumed with pharmaceutical drugs. Understanding mechanisms of NPDIs is key to preventing adverse events. We constructed a knowledge…

PubMed is an essential resource for the medical domain, but useful concepts are either difficult to extract or are ambiguated, which has significantly hindered knowledge discovery. To address this issue, we constructed a PubMed knowledge…

OBJECTIVE: Leverage existing biomedical NLP tools and DS domain terminology to produce a novel and comprehensive knowledge graph containing dietary supplement (DS) information for discovering interactions between DS and drugs, or…

Thanks to the increasing availability of drug-drug interactions (DDI) datasets and large biomedical knowledge graphs (KGs), accurate detection of adverse DDI using machine learning models becomes possible. However, it remains largely an…

Machine Learning · Computer Science 2021-05-10 Yue Yu , Kexin Huang , Chao Zhang , Lucas M. Glass , Jimeng Sun , Cao Xiao

Biomedical knowledge graphs (KGs) encode vast, heterogeneous information spanning literature, genes, pathways, drugs, diseases, and clinical trials, but leveraging them collectively for scientific discovery remains difficult. Their…

Information Retrieval · Computer Science 2026-01-21 Zifeng Wang , Zheng Chen , Ziwei Yang , Xuan Wang , Qiao Jin , Yifan Peng , Zhiyong Lu , Jimeng Sun

Business Knowledge Graphs (KGs) are important to many enterprises today, providing factual knowledge and structured data that steer many products and make them more intelligent. Despite their promising benefits, building business KG…

The rapid expansion of e-commerce platforms generates vast amounts of unstructured product data, creating significant challenges for information retrieval, recommendation systems, and data analytics. Knowledge Graphs (KGs) offer a…

Artificial Intelligence · Computer Science 2025-11-17 Dimitar Peshevski , Riste Stojanov , Dimitar Trajanov

Large Language Models (LLMs) have shown remarkable capabilities across various tasks but remain prone to hallucinations in knowledge-intensive scenarios. Knowledge Base Question Answering (KBQA) mitigates this by grounding generation in…

Computation and Language · Computer Science 2026-04-15 Shuai Wang , Xixi Wang , Yinan Yu

Biomedical research is growing at such an exponential pace that scientists, researchers, and practitioners are no more able to cope with the amount of published literature in the domain. The knowledge presented in the literature needs to be…

Artificial Intelligence · Computer Science 2024-07-09 Nikola Milosevic , Wolfgang Thielemann

Schema matching is a critical task in data integration, particularly in the medical domain where disparate Electronic Health Record (EHR) systems must be aligned to standard models like OMOP CDM. While Large Language Models (LLMs) have…

Artificial Intelligence · Computer Science 2025-12-02 Mingyu Jeon , Jaeyoung Suh , Suwan Cho

Knowledge graphs and ontologies represent entities and their relationships in a structured way, having gained significance in the development of modern AI applications. Integrating these semantic resources with machine learning models often…

Machine Learning · Computer Science 2025-09-10 Hamid Ahmad , Heiko Paulheim , Rita T. Sousa

Network pharmacology (NP) explores pharmacological mechanisms through biological networks. Multi-omics data enable multi-layer network construction under diverse conditions, requiring integration into NP analyses. We developed POINT, a…

Molecular Networks · Quantitative Biology 2025-03-11 Zihao He , Liu Liu , Dongchen Han , Kai Gao , Lei Dong , Dechao Bu , Peipei Huo , Zhihao Wang , Wenxin Deng , Jingjia Liu , Jin-cheng Guo , Yi Zhao , Yang Wu

To tackle the problem of domain-specific knowledge scarcity within large language models (LLMs), knowledge graph-retrievalaugmented method has been proven to be an effective and efficient technique for knowledge infusion. However, existing…

Computation and Language · Computer Science 2024-06-07 Zhouyu Jiang , Ling Zhong , Mengshu Sun , Jun Xu , Rui Sun , Hui Cai , Shuhan Luo , Zhiqiang Zhang

Structured and unstructured data and facts about drugs, genes, protein, viruses, and their mechanism are spread across a huge number of scientific articles. These articles are a large-scale knowledge source and can have a huge impact on…

Artificial Intelligence · Computer Science 2022-10-13 Md. Rezaul Karim , Hussain Ali , Prinon Das , Mohamed Abdelwaheb , Stefan Decker

Drug-drug interactions (DDIs) remain a major source of preventable harm, and many clinically important mechanisms are still unknown. Existing models either rely on pharmacologic knowledge graphs (KGs), which fail on unseen drugs, or on…

Machine Learning · Computer Science 2025-11-11 Franklin Lee , Tengfei Ma

This comprehensive review aims to provide an overview of the current state of Healthcare Knowledge Graphs (HKGs), including their construction, utilization models, and applications across various healthcare and biomedical research domains.…

In the last decades, people have been consuming and combining more drugs than before, increasing the number of Drug-Drug Interactions (DDIs). To predict unknown DDIs, recently, studies started incorporating Knowledge Graphs (KGs) since they…

Artificial Intelligence · Computer Science 2023-08-14 Lizzy Farrugia , Lilian M. Azzopardi , Jeremy Debattista , Charlie Abela

The increasing reliance on Large Language Models (LLMs) for health information seeking can pose severe risks due to the potential for misinformation and the complexity of these topics. This paper introduces KNOWNET a visualization system…

Human-Computer Interaction · Computer Science 2024-09-27 Youfu Yan , Yu Hou , Yongkang Xiao , Rui Zhang , Qianwen Wang