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In healthcare, it is essential to explain the decision-making process of machine learning models to establish the trustworthiness of clinicians. This paper introduces BI-RADS-Net, a novel explainable deep learning approach for cancer…

Computer Vision and Pattern Recognition · Computer Science 2021-10-11 Boyu Zhang , Aleksandar Vakanski , Min Xian

Pathology is the study of microscopic inspection of tissue, and a pathology diagnosis is often the medical gold standard to diagnose disease. Pathology images provide a unique challenge for computer-vision-based analysis: a single pathology…

Accurate classification of laryngeal vascular as benign or malignant is crucial for early detection of laryngeal cancer. However, organizations with limited access to laryngeal vascular images face challenges due to the lack of large and…

Computer Vision and Pattern Recognition · Computer Science 2025-01-17 Xinyi Fang , Xu Yang , Chak Fong Chong , Kei Long Wong , Yapeng Wang , Tiankui Zhang , Sio-Kei Im

This paper presents a novel approach to accurately classify the hallmarks of cancer, which is a crucial task in cancer research. Our proposed method utilizes the Bidirectional Encoder Representations from Transformers (BERT) architecture,…

Computation and Language · Computer Science 2023-06-08 Sultan Zavrak , Seyhmus Yilmaz

The rapid development of digital pathology and modern deep learning has facilitated the emergence of pathology foundation models that are expected to solve general pathology problems under various disease conditions in one unified model,…

Computer Vision and Pattern Recognition · Computer Science 2025-07-10 Yutong Sun , Sichen Zhu , Peng Qiu

Diffusion MRI tractography technique enables non-invasive visualization of the white matter pathways in the brain. It plays a crucial role in neuroscience and clinical fields by facilitating the study of brain connectivity and neurological…

Computer Vision and Pattern Recognition · Computer Science 2025-03-06 Yiqiong Yang , Yitian Yuan , Baoxing Ren , Ye Wu , Yanqiu Feng , Xinyuan Zhang

Prevention and early diagnosis of breast cancer (BC) is an essential prerequisite for the selection of proper treatment. The substantial pressure due to the increase of demand for faster and more precise diagnostic results drives for…

Image and Video Processing · Electrical Eng. & Systems 2021-06-29 Peter Bokor , Lukas Hudec , Ondrej Fabian , Wanda Benesova

Cancer is the second leading cause of death in the world. Diagnosing cancer early on can save many lives. Pathologists have to look at tissue microarray (TMA) images manually to identify tumors, which can be time-consuming, inconsistent and…

Machine Learning · Computer Science 2024-09-04 Iris Yan

We present WeakSTIL, an interpretable two-stage weak label deep learning pipeline for scoring the percentage of stromal tumor infiltrating lymphocytes (sTIL%) in H&E-stained whole-slide images (WSIs) of breast cancer tissue. The sTIL% score…

Image and Video Processing · Electrical Eng. & Systems 2021-09-14 Yoni Schirris , Mendel Engelaer , Andreas Panteli , Hugo Mark Horlings , Efstratios Gavves , Jonas Teuwen

Current multimodal fusion approaches in computational oncology primarily focus on integrating multi-gigapixel histology whole slide images (WSIs) with genomic or transcriptomic data, demonstrating improved survival prediction. We…

Computer Vision and Pattern Recognition · Computer Science 2025-09-25 Manahil Raza , Ayesha Azam , Talha Qaiser , Nasir Rajpoot

The integration of AI in digital pathology, particularly in whole slide image (WSI) and spatial transcriptomics (ST) analysis, holds immense potential for enhancing our understanding of diseases. Despite challenges such as training pattern…

Quantitative Methods · Quantitative Biology 2024-11-18 Chao-Hui Huang , Sara Lichtarge , Diane Fernandez

Clinical cystoscopy, the current standard for bladder cancer diagnosis, suffers from significant reliance on physician expertise, leading to variability and subjectivity in diagnostic outcomes. There is an urgent need for objective,…

Image and Video Processing · Electrical Eng. & Systems 2025-08-22 Jinliang Yu , Mingduo Xie , Yue Wang , Tianfan Fu , Xianglai Xu , Jiajun Wang

Brain tumors present a grave risk to human life, demanding precise and timely diagnosis for effective treatment. Inaccurate identification of brain tumors can significantly diminish life expectancy, underscoring the critical need for…

Image and Video Processing · Electrical Eng. & Systems 2025-06-10 Md. Alamin Talukder , Md. Manowarul Islam , Md Ashraf Uddin

Representation learning of the task-oriented attention while tracking instrument holds vast potential in image-guided robotic surgery. Incorporating cognitive ability to automate the camera control enables the surgeon to concentrate more on…

Computer Vision and Pattern Recognition · Computer Science 2021-12-16 Mobarakol Islam , Vibashan VS , Chwee Ming Lim , Hongliang Ren

Predicting the risk of developing breast cancer is an important clinical tool to guide early intervention and tailoring personalized screening strategies. Early risk models have limited performance and recently machine learning-based…

Image and Video Processing · Electrical Eng. & Systems 2025-05-29 Zhengbo Zhou , Dooman Arefan , Margarita Zuley , Jules Sumkin , Shandong Wu

Tumor burden assessment by magnetic resonance imaging (MRI) is central to the evaluation of treatment response for glioblastoma. This assessment is complex to perform and associated with high variability due to the high heterogeneity and…

Brain tumor is one of the leading causes of cancer death. The high-grade brain tumors are easier to recurrent even after standard treatment. Therefore, developing a method to predict brain tumor recurrence location plays an important role…

Image and Video Processing · Electrical Eng. & Systems 2023-04-28 Tongxue Zhou , Alexandra Noeuveglise , Romain Modzelewski , Fethi Ghazouani , Sébastien Thureau , Maxime Fontanilles , Su Ruan

Iris segmentation is a deterministic part of the iris recognition system. Unreliable segmentation of iris regions especially the limbic area is still the bottleneck problem, which impedes more accurate recognition. To make further efforts…

Computer Vision and Pattern Recognition · Computer Science 2021-11-19 Jianze Wei , Huaibo Huang , Muyi Sun , Yunlong Wang , Min Ren , Ran He , Zhenan Sun

The rapidly emerging field of deep learning-based computational pathology has shown promising results in utilizing whole slide images (WSIs) to objectively prognosticate cancer patients. However, most prognostic methods are currently…

Computer Vision and Pattern Recognition · Computer Science 2023-11-21 Mingxin Liu , Yunzan Liu , Hui Cui , Chunquan Li , Jiquan Ma

Spatial transcriptomics enables interrogating the molecular composition of tissue with ever-increasing resolution and sensitivity. However, costs, rapidly evolving technology, and lack of standards have constrained computational methods in…

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