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Movement and pose assessment of newborns lets experienced pediatricians predict neurodevelopmental disorders, allowing early intervention for related diseases. However, most of the newest AI approaches for human pose estimation methods…

Computer Vision and Pattern Recognition · Computer Science 2022-12-27 Xu Cao , Xiaoye Li , Liya Ma , Yi Huang , Xuan Feng , Zening Chen , Hongwu Zeng , Jianguo Cao

State-of-the-art whole-body pose estimators often lack robustness, producing anatomically implausible predictions in challenging scenes. We posit this failure stems from spurious correlations learned from visual context, a problem we…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Bohao Li , Zhicheng Cao , Huixian Li , Yangming Guo

Designing antibody sequences to better resemble those observed in natural human repertoires is a key challenge in biologics development. We introduce IgCraft: a multi-purpose model for paired human antibody sequence generation, built on…

Biomolecules · Quantitative Biology 2025-04-16 Matthew Greenig , Haowen Zhao , Vladimir Radenkovic , Aubin Ramon , Pietro Sormanni

Understanding the structure of the protein-ligand complex is crucial to drug development. Existing virtual structure measurement and screening methods are dominated by docking and its derived methods combined with deep learning. However,…

Artificial Intelligence · Computer Science 2024-08-22 Kelei He , Tiejun Dong , Jinhui Wu , Junfeng Zhang

Relative pose estimation is fundamental for SLAM, visual localization, and 3D reconstruction. Existing Relative Pose Regression (RPR) methods face a key trade-off: feature-matching pipelines achieve high accuracy but block gradient flow via…

Computer Vision and Pattern Recognition · Computer Science 2026-03-23 Jun Wang , Xiaoyan Huang

We present GigaPose, a fast, robust, and accurate method for CAD-based novel object pose estimation in RGB images. GigaPose first leverages discriminative "templates", rendered images of the CAD models, to recover the out-of-plane rotation…

Computer Vision and Pattern Recognition · Computer Science 2024-03-18 Van Nguyen Nguyen , Thibault Groueix , Mathieu Salzmann , Vincent Lepetit

This letter presents KGpose, a novel end-to-end framework for 6D pose estimation of multiple objects. Our approach combines keypoint-based method with learnable pose regression through `keypoint-graph', which is a graph representation of…

Computer Vision and Pattern Recognition · Computer Science 2024-07-15 Andrew Jeong

We propose a sparse end-to-end multi-person pose regression framework, termed QueryPose, which can directly predict multi-person keypoint sequences from the input image. The existing end-to-end methods rely on dense representations to…

Computer Vision and Pattern Recognition · Computer Science 2022-12-16 Yabo Xiao , Kai Su , Xiaojuan Wang , Dongdong Yu , Lei Jin , Mingshu He , Zehuan Yuan

Recent advancements in computer vision have seen a rise in the prominence of applications using neural networks to understand human poses. However, while accuracy has been steadily increasing on State-of-the-Art datasets, these datasets…

Computer Vision and Pattern Recognition · Computer Science 2022-06-10 Ghazal Alinezhad Noghre , Armin Danesh Pazho , Justin Sanchez , Nathan Hewitt , Christopher Neff , Hamed Tabkhi

Learning 3D human pose prior is essential to human-centered AI. Here, we present GFPose, a versatile framework to model plausible 3D human poses for various applications. At the core of GFPose is a time-dependent score network, which…

Computer Vision and Pattern Recognition · Computer Science 2022-12-19 Hai Ci , Mingdong Wu , Wentao Zhu , Xiaoxuan Ma , Hao Dong , Fangwei Zhong , Yizhou Wang

6D pose recognition has been a crucial factor in the success of robotic grasping, and recent deep learning based approaches have achieved remarkable results on benchmarks. However, their generalization capabilities in real-world…

Computer Vision and Pattern Recognition · Computer Science 2023-03-10 Hongpeng Cao , Lukas Dirnberger , Daniele Bernardini , Cristina Piazza , Marco Caccamo

AI-powered drug discovery typically relies on the successful prediction of compound-protein interactions, which are pivotal for the evaluation of designed compound molecules in structure-based drug design and represent a core challenge in…

Biomolecules · Quantitative Biology 2025-04-22 Pingfei Zhu , Chenyang Zhao , Haishi Zhao , Bo Yang

Recent works on pose-based gait recognition have demonstrated the potential of using such simple information to achieve results comparable to silhouette-based methods. However, the generalization ability of pose-based methods on different…

Computer Vision and Pattern Recognition · Computer Science 2023-08-16 Yang Fu , Shibei Meng , Saihui Hou , Xuecai Hu , Yongzhen Huang

Deep learning promises to dramatically improve scoring functions for molecular docking, leading to substantial advances in binding pose prediction and virtual screening. To train scoring functions-and to perform molecular docking-one must…

Biomolecules · Quantitative Biology 2023-12-04 Patricia Suriana , Ron O. Dror

Egocentric 3D human pose estimation remains challenging due to severe perspective distortion, limited body visibility, and complex camera motion inherent in first-person viewpoints. Existing methods typically rely on single-frame analysis…

Computer Vision and Pattern Recognition · Computer Science 2026-03-27 Md Mushfiqur Azam , John Quarles , Kevin Desai

Recent advancements in protein design have leveraged diffusion models to generate structural scaffolds, followed by a process known as protein inverse folding, which involves sequence inference on these scaffolds. However, these…

Biomolecules · Quantitative Biology 2025-02-27 Xingyi Zhang , Kun Xie , Ningqiao Huang , Wei Liu , Peilin Zhao , Sibo Wang , Kangfei Zhao , Biaobin Jiang

Despite substantial progress in 3D human pose estimation from a single-view image, prior works rarely explore global and local correlations, leading to insufficient learning of human skeleton representations. To address this issue, we…

Computer Vision and Pattern Recognition · Computer Science 2023-04-28 Ti Wang , Hong Liu , Runwei Ding , Wenhao Li , Yingxuan You , Xia Li

We introduce IgDiff, an antibody variable domain diffusion model based on a general protein backbone diffusion framework which was extended to handle multiple chains. Assessing the designability and novelty of the structures generated with…

Biomolecules · Quantitative Biology 2024-05-14 Daniel Cutting , Frédéric A. Dreyer , David Errington , Constantin Schneider , Charlotte M. Deane

RGB-based novel object pose estimation is critical for rapid deployment in robotic applications, yet zero-shot generalization remains a key challenge. In this paper, we introduce PicoPose, a novel framework designed to tackle this task…

Computer Vision and Pattern Recognition · Computer Science 2025-09-01 Lihua Liu , Jiehong Lin , Zhenxin Liu , Kui Jia

We introduce HybridPose, a novel 6D object pose estimation approach. HybridPose utilizes a hybrid intermediate representation to express different geometric information in the input image, including keypoints, edge vectors, and symmetry…

Computer Vision and Pattern Recognition · Computer Science 2020-10-19 Chen Song , Jiaru Song , Qixing Huang
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