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The two main thrusts of computational science are more accurate predictions and faster calculations; to this end, the zeitgeist in molecular dynamics (MD) simulations is pursuing machine learned and data driven interatomic models, e.g.…

Computational Physics · Physics 2020-02-24 Saaketh Desai , Samuel Temple Reeve , James F. Belak

Agent-based cellular models simulate tissue evolution by capturing the behavior of individual cells, their interactions with neighboring cells, and their responses to the surrounding microenvironment. An important challenge in the field is…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-02-06 Jose-Luis Estragues-Muñoz , Carlos Alvarez , Arnau Montagud , Daniel Jimenez-Gonzalez , Alfonso Valencia

This article introduces a highly parallel algorithm for molecular dynamics simulations with short-range forces on single node multi- and many-core systems. The algorithm is designed to achieve high parallel speedups for strongly…

Computational Physics · Physics 2013-11-20 R. Meyer

We present in this paper our work regarding simulating a type of P system known as a spiking neural P system (SNP system) using graphics processing units (GPUs). GPUs, because of their architectural optimization for parallel computations,…

Distributed, Parallel, and Cluster Computing · Computer Science 2011-04-13 Francis Cabarle , Henry Adorna , Miguel A. Martinez-del-Amor

We present a novel, hardware-agnostic implementation strategy for lattice Boltzmann (LB) simulations, which yields massive performance on homogeneous and heterogeneous many-core platforms. Based solely on C++17 Parallel Algorithms, our…

Computational Physics · Physics 2021-05-11 Jonas Latt , Christophe Coreixas , Joël Beny

Bloom filters are a fundamental data structure for approximate membership queries, with applications ranging from data analytics to databases and genomics. Several variants have been proposed to accommodate parallel architectures. GPUs,…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-12-18 Daniel Jünger , Kevin Kristensen , Yunsong Wang , Xiangyao Yu , Bertil Schmidt

In this paper we solve on GPUs massive problems with large amount of data, which are not appropriate for solution with the SIMD technology. For the given problem we consider a three-level parallelization. The multithreading of CPU is used…

Distributed, Parallel, and Cluster Computing · Computer Science 2014-02-18 Natalya Litvinenko

Real-world applications are now processing big-data sets, often bottlenecked by the data movement between the compute units and the main memory. Near-memory computing (NMC), a modern data-centric computational paradigm, can alleviate these…

Hardware Architecture · Computer Science 2021-06-30 Stefano Corda , Madhurya Kumaraswamy , Ahsan Javed Awan , Roel Jordans , Akash Kumar , Henk Corporaal

We consider a parallel computational model that consists of $P$ processors, each with a fast local ephemeral memory of limited size, and sharing a large persistent memory. The model allows for each processor to fault with bounded…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-06-15 Guy E. Blelloch , Phillip B. Gibbons , Yan Gu , Charles McGuffey , Julian Shun

In the last three years, the largest dense deep learning models have grown over 1000x to reach hundreds of billions of parameters, while the GPU memory has only grown by 5x (16 GB to 80 GB). Therefore, the growth in model scale has been…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-04-19 Samyam Rajbhandari , Olatunji Ruwase , Jeff Rasley , Shaden Smith , Yuxiong He

Video diffusion models (VDMs) perform attention computation over the 3D spatio-temporal domain. Compared to large language models (LLMs) processing 1D sequences, their memory consumption scales cubically, necessitating parallel serving…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-12-09 Zhiyuan Wu , Shuai Wang , Li Chen , Kaihui Gao , Dan Li , Yanyu Ren , Qiming Zhang , Yong Wang

To achieve high performance on modern computers, it is vital to map algorithmic parallelism to that inherent in the hardware. From an application developer's perspective, it is also important that code can be maintained in a portable manner…

Distributed, Parallel, and Cluster Computing · Computer Science 2016-06-20 Alan Gray , Kevin Stratford

Mixture of Experts (MoE) models enhance neural network scalability by dynamically selecting relevant experts per input token, enabling larger model sizes while maintaining manageable computation costs. However, efficient training of…

We introduce a variant of the Gatenby-Gawlinski model for acid-mediated tumor invasion, accounting for anisotropic and heterogeneous diffusion of the lactic acid across the surrounding healthy tissues. Numerical simulations are performed…

Medical Physics · Physics 2020-06-03 Corrado Mascia , Donato Pera , Chiara Simeoni

Current multi-agent Large Language Model (LLM) frameworks suffer from linear memory scaling, rendering "System 2" parallel reasoning impractical on consumer hardware. We present Warp Cortex, an asynchronous architecture that theoretically…

Machine Learning · Computer Science 2026-01-06 Jorge L. Ruiz Williams

Typical biomolecular systems such as cellular membranes, DNA, and protein complexes are highly charged. Thus, efficient and accurate treatment of electrostatic interactions is of great importance in computational modelling of such systems.…

Soft Condensed Matter · Physics 2007-05-23 Michael Patra , Marja T. Hyvonen , Emma Falck , Mohsen Sabouri-Ghomi , Ilpo Vattulainen , Mikko Karttunen

In this work, we have developed a multiscale computational algorithm to couple finite element method with an open source molecular dynamics code --- the Large scale Atomic/Molecular Massively Parallel Simulator (LAMMPS) --- to perform…

Soft Condensed Matter · Physics 2019-09-17 Takahiro Murashima , Shingo Urata , Shaofan Li

Molecular dynamics simulations can generate atomically detailed trajectories of complex systems, but analyzing these dynamics can be challenging when systems lack well-established quantitative descriptors (features). Graph neural networks…

Machine Learning · Computer Science 2025-12-09 Zihan Pengmei , Spencer C. Guo , Chatipat Lorpaiboon , Aaron R. Dinner

Large-scale recommendation systems are pivotal to process an immense volume of daily user interactions, requiring the effective modeling of high cardinality and heterogeneous features to ensure accurate predictions. In prior work, we…

Information Retrieval · Computer Science 2025-08-19 Yue Dong , Han Li , Shen Li , Nikhil Patel , Xing Liu , Xiaodong Wang , Chuanhao Zhuge

The latest trends in high-performance computing systems show an increasing demand on the use of a large scale multicore systems in a efficient way, so that high compute-intensive applications can be executed reasonably well. However, the…

Distributed, Parallel, and Cluster Computing · Computer Science 2013-02-25 Juliana M. N. Silva , Cristina Boeres , Lúcia M. A. Drummond , Artur A. Pessoa