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We propose a dual pathway, 11-layers deep, three-dimensional Convolutional Neural Network for the challenging task of brain lesion segmentation. The devised architecture is the result of an in-depth analysis of the limitations of current…

Computer Vision and Pattern Recognition · Computer Science 2017-01-10 Konstantinos Kamnitsas , Christian Ledig , Virginia F. J. Newcombe , Joanna P. Simpson , Andrew D. Kane , David K. Menon , Daniel Rueckert , Ben Glocker

Diffusion MRI (dMRI) is a valuable imaging technique to study the brain in vivo. However, the resolution of dMRI is limited by the low signal-to-noise ratio (SNR) of this technique. Various acquisition strategies have been developed to…

Medical Physics · Physics 2023-05-30 Sajjad Feizollah , Christine L. Tardif

Neuroanatomical segmentation in magnetic resonance imaging (MRI) of the brain is a prerequisite for volume, thickness and shape measurements. This work introduces a new highly accurate and versatile method based on 3D convolutional neural…

Quantitative Methods · Quantitative Biology 2019-02-07 Philip Novosad , Vladimir Fonov , D. Louis Collins

High-resolution (HR) magnetic resonance images (MRI) provide detailed anatomical information important for clinical application and quantitative image analysis. However, HR MRI conventionally comes at the cost of longer scan time, smaller…

Computer Vision and Pattern Recognition · Computer Science 2018-06-12 Yuhua Chen , Feng Shi , Anthony G. Christodoulou , Zhengwei Zhou , Yibin Xie , Debiao Li

Purpose: To implement a brain segmentation pipeline based on convolutional neural networks, which rapidly segments 3D volumes into 27 anatomical structures. To provide an extensive, comparative study of segmentation performance on various…

Image and Video Processing · Electrical Eng. & Systems 2020-08-12 Jonathan Zopes , Moritz Platscher , Silvio Paganucci , Christian Federau

Background: Three-dimensional, whole heart, balanced steady state free precession (WH-bSSFP) sequences provide delineation of intra-cardiac and vascular anatomy. However, they have long acquisition times. Here, we propose significant speed…

Image and Video Processing · Electrical Eng. & Systems 2019-12-24 Jennifer A. Steeden , Michael Quail , Alexander Gotschy , Andreas Hauptmann , Simon Arridge , Rodney Jones , Vivek Muthurangu

Magnetic Resonance Spectroscopic Imaging (MRSI) is a powerful tool for non-invasive mapping of brain metabolites, providing critical insights into neurological conditions. However, its utility is often limited by missing or corrupted data…

Image and Video Processing · Electrical Eng. & Systems 2025-05-13 Tan-Hanh Pham , Ovidiu C. Andronesi , Xianqi Li , Kim-Doang Nguyen

Medical image super-resolution (MedSR) is essential for improving diagnostic precision across diverse imaging modalities such as MRI, CT, X-ray, Ultrasound, and Fundus imaging. Despite rapid advances in deep learning, challenges remain in…

Computer Vision and Pattern Recognition · Computer Science 2026-05-06 Subhash Gurappa , Trivikram Satharasi , Yashas Hariprasad , Sundararaj Sitharama Iyengar

We propose ReMiDi, a novel method for inferring neuronal microstructure as arbitrary 3D meshes using a differentiable diffusion Magnetic Resonance Imaging (dMRI) simulator. We first implemented in PyTorch a differentiable dMRI simulator…

Image and Video Processing · Electrical Eng. & Systems 2025-03-03 Prathamesh Pradeep Khole , Zahra Kais Petiwala , Shri Prathaa Magesh , Ehsan Mirafzali , Utkarsh Gupta , Jing-Rebecca Li , Andrada Ianus , Razvan Marinescu

In this paper we propose a 2D deep residual Unet with 104 convolutional layers (DR-Unet104) for lesion segmentation in brain MRIs. We make multiple additions to the Unet architecture, including adding the 'bottleneck' residual block to the…

Image and Video Processing · Electrical Eng. & Systems 2021-05-05 Jordan Colman , Lei Zhang , Wenting Duan , Xujiong Ye

Segmentation in 3D scans is playing an increasingly important role in current clinical practice supporting diagnosis, tissue quantification, or treatment planning. The current 3D approaches based on convolutional neural networks usually…

Computer Vision and Pattern Recognition · Computer Science 2019-03-12 Alexey Novikov , David Major , Maria Wimmer , Dimitrios Lenis , Katja Bühler

Volumetric biomedical microscopy has the potential to increase the diagnostic information extracted from clinical tissue specimens and improve the diagnostic accuracy of both human pathologists and computational pathology models.…

Image and Video Processing · Electrical Eng. & Systems 2024-04-16 Cheng Jiang , Alexander Gedeon , Yiwei Lyu , Eric Landgraf , Yufeng Zhang , Xinhai Hou , Akhil Kondepudi , Asadur Chowdury , Honglak Lee , Todd Hollon

In this paper, a 3D patch-based fully dense and fully convolutional network (FD-FCN) is proposed for fast and accurate segmentation of subcortical structures in T1-weighted magnetic resonance images. Developed from the seminal FCN with an…

Image and Video Processing · Electrical Eng. & Systems 2020-05-01 Binbin Yang , Weiwei Zhang

Segmentation of brain structures on MRI is the primary step for further quantitative analysis of brain diseases. Manual segmentation is still considered the gold standard in terms of accuracy; however, such data is extremely time-consuming…

Image and Video Processing · Electrical Eng. & Systems 2024-10-16 Mengyu Li , Magnus Magnusson , Thilo van Eimeren , Lotta M. Ellingsen

High-resolution diffusion tensor imaging (DTI) is beneficial for probing tissue microstructure in fine neuroanatomical structures, but long scan times and limited signal-to-noise ratio pose significant barriers to acquiring DTI at…

Image and Video Processing · Electrical Eng. & Systems 2021-02-19 Qiyuan Tian , Ziyu Li , Qiuyun Fan , Chanon Ngamsombat , Yuxin Hu , Congyu Liao , Fuyixue Wang , Kawin Setsompop , Jonathan R. Polimeni , Berkin Bilgic , Susie Y. Huang

In this work we propose an adversarial learning approach to generate high resolution MRI scans from low resolution images. The architecture, based on the SRGAN model, adopts 3D convolutions to exploit volumetric information. For the…

Computer Vision and Pattern Recognition · Computer Science 2019-01-01 Irina Sanchez , Veronica Vilaplana

Purpose: To propose a self-supervised deep learning-based compressed sensing MRI (DL-based CS-MRI) method named "Adaptive Self-Supervised Consistency Guided Diffusion Model (ASSCGD)" to accelerate data acquisition without requiring fully…

Image and Video Processing · Electrical Eng. & Systems 2025-02-11 Mojtaba Safari , Zach Eidex , Shaoyan Pan , Richard L. J. Qiu , Xiaofeng Yang

Diffusion Magnetic Resonance Imaging (dMRI) is a non-invasive method for depicting brain microstructure in vivo. Fiber orientation distributions (FODs) are mathematical representations extensively used to map white matter fiber…

Image and Video Processing · Electrical Eng. & Systems 2025-04-22 Rizhong Lin , Hamza Kebiri , Ali Gholipour , Yufei Chen , Jean-Philippe Thiran , Davood Karimi , Meritxell Bach Cuadra

Medical imaging modalities are inherently susceptible to noise contamination that degrades diagnostic utility and clinical assessment accuracy. This paper presents a comprehensive comparative evaluation of three state-of-the-art deep…

Image and Video Processing · Electrical Eng. & Systems 2025-08-26 Asadullah Bin Rahman , Masud Ibn Afjal , Md. Abdulla Al Mamun

Deep learning models in medical contexts face challenges like data scarcity, inhomogeneity, and privacy concerns. This study focuses on improving ventricular segmentation in brain MRI images using synthetic data. We employed two latent…

Computer Vision and Pattern Recognition · Computer Science 2024-11-05 Tim Ruschke , Jonathan Frederik Carlsen , Adam Espe Hansen , Ulrich Lindberg , Amalie Monberg Hindsholm , Martin Norgaard , Claes Nøhr Ladefoged
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