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Quantum machine learning is one of the many potential applications of quantum computing, each of which is hoped to provide some novel computational advantage. However, quantum machine learning applications often fail to outperform classical…

Quantum Physics · Physics 2025-11-07 Gennaro De Luca , Andrew Vlasic , Michael Vitz , Anh Pham

Parametrized quantum circuits initialized with random initial parameter values are characterized by barren plateaus where the gradient becomes exponentially small in the number of qubits. In this technical note we theoretically motivate and…

Quantum Physics · Physics 2019-12-11 Edward Grant , Leonard Wossnig , Mateusz Ostaszewski , Marcello Benedetti

Quantum generative models use the intrinsic probabilistic nature of quantum mechanics to learn and reproduce complex probability distributions. In this paper, we present an implementation of a 3-qubit quantum circuit Born machine trained to…

Quantum Physics · Physics 2025-08-04 Soumyadip Sarkar

Generative quantum machine learning models are trained to deduce the probability distribution underlying a given dataset, and to produce new, synthetic samples from it. The majority of such models proposed in the literature, like the…

Quantum Physics · Physics 2026-03-25 Michael Krebsbach , Florentin Reiter , Thomas Wellens , Hagen-Henrik Kowalski , Ali Abedi

Longitudinal biomedical studies play a vital role in tracking disease progression, treatment response, and the emergence of resistance mechanisms, particularly in complex disorders such as cancer and neurodegenerative diseases. However, the…

Quantitative Methods · Quantitative Biology 2025-04-28 Maria Demidik , Filippo Utro , Alexey Galda , Karl Jansen , Daniel Blankenberg , Laxmi Parida

There has been intensive research on increasing the utility and performance of Parameterized Quantum Circuits (PQCs) in the past couple of years. Owing to this research, there are now several inductive biases available to a quantum…

Quantum Physics · Physics 2026-04-24 Ankit Kulshrestha , Sarvagya Upadhyay

The class of commuting quantum circuits known as IQP (instantaneous quantum polynomial-time) has been shown to be hard to simulate classically, assuming certain complexity-theoretic conjectures. Here we study the power of IQP circuits in…

Quantum Physics · Physics 2017-04-26 Michael J. Bremner , Ashley Montanaro , Dan J. Shepherd

We study the problem of training and certifying adversarially robust quantized neural networks (QNNs). Quantization is a technique for making neural networks more efficient by running them using low-bit integer arithmetic and is therefore…

Machine Learning · Computer Science 2022-11-30 Mathias Lechner , Đorđe Žikelić , Krishnendu Chatterjee , Thomas A. Henzinger , Daniela Rus

Generative modeling is a flavor of machine learning with applications ranging from computer vision to chemical design. It is expected to be one of the techniques most suited to take advantage of the additional resources provided by…

Quantum generative models exploit quantum superposition and entanglement to enhance learning efficiency for both classical and quantum data. Recently, inspired by classical diffusion frameworks, the quantum denoising diffusion probabilistic…

Machine Learning · Computer Science 2026-04-16 Haipeng Cao , Kaining Zhang , Dacheng Tao , Zhaofeng Su

Quantum mechanics is inherently probabilistic in light of Born's rule. Using quantum circuits as probabilistic generative models for classical data exploits their superior expressibility and efficient direct sampling ability. However,…

Quantum Physics · Physics 2019-05-15 Jinfeng Zeng , Yufeng Wu , Jin-Guo Liu , Lei Wang , Jiangping Hu

Generative modelling is an important unsupervised task in machine learning. In this work, we study a hybrid quantum-classical approach to this task, based on the use of a quantum circuit Born machine. In particular, we consider training a…

Quantum Physics · Physics 2021-10-11 Chiara Leadbeater , Louis Sharrock , Brian Coyle , Marcello Benedetti

Quantum randomness relies heavily on the accurate characterization of the generator implementation, where the device imperfection or inaccurate characterization can lead to incorrect entropy estimation and practical bias, significantly…

Quantum Physics · Physics 2024-09-12 You-Qi Nie , Hongyi Zhou , Bing Bai , Qi Xu , Xiongfeng Ma , Jun Zhang , Jian-Wei Pan

Quantum machine learning for classical data is currently perceived to have a scalability problem due to (i) a bottleneck at the point of loading data into quantum states, (ii) the lack of clarity around good optimization strategies, and…

Quantum Physics · Physics 2025-01-09 Sonika Johri

Variational quantum algorithms are promising candidates for near-term quantum computing but can be hindered by barren plateaus, where gradients vanish exponentially and optimization becomes intractable. Noise-Induced Barren Plateaus (NIBP)…

Quantum Physics · Physics 2026-03-10 Sebastian Schmitt , Linus Ekstrøm , Alberto Bottarelli , Xavier Bonet-Monroig

Quantum Supremacy is a demonstration of a computation by a quantum computer that can not be performed by the best classical computer in a reasonable time. A well-studied approach to demonstrating this on near-term quantum computers is to…

Quantum Physics · Physics 2025-09-22 Julien Codsi , John van de Wetering

The impressive progress in fabricating and controlling superconducting devices for quantum information processing has reached a level where reliable theoretical predictions need to account for quantum correlations that are not captured by…

When compared to fault-tolerant quantum computational strategies, variational quantum algorithms stand as one of the candidates with the potential of achieving quantum advantage for real-world applications in the near term. However, the…

In this work, we aim at augmenting the decisions output by quantum models with "error bars" that provide finite-sample coverage guarantees. Quantum models implement implicit probabilistic predictors that produce multiple random decisions…

Quantum Physics · Physics 2023-10-24 Sangwoo Park , Osvaldo Simeone

Understanding the theoretical capabilities and limitations of quantum machine learning (QML) models to solve machine learning tasks is crucial to advancing both quantum software and hardware developments. Similarly to the classical setting,…

Quantum Physics · Physics 2026-03-31 Qiuhao Chen , Yuling Jiao , Yinan Li , Xiliang Lu , Jerry Zhijian Yang