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The dynamics of growth of bacterial populations has been extensively studied for planktonic cells in well-agitated liquid culture, in which all cells have equal access to nutrients. In the real world, bacteria are more likely to live in…

Populations and Evolution · Quantitative Biology 2017-11-01 Xinxian Shao , Andrew Mugler , Justin Kim , Ha Jun Jeong , Bruce Levin , Ilya Nemenman

We study the chemotaxis of a population of genetically identical swimming bacteria undergoing run and tumble dynamics driven by stochastic switching between clockwise and counterclockwise rotation of the flagellar rotary system.…

Cell Behavior · Quantitative Biology 2020-07-17 Margaritis Voliotis , Jerko Rosko , Teuta Pilizota , Tanniemola Liverpool

We study analytically the dynamics and the micro-structural changes of a host medium caused by a driven tracer particle moving in a confined, quiescent molecular crowding environment. Imitating typical settings of active micro-rheology…

Statistical Mechanics · Physics 2016-03-17 O. Bénichou , P. Illien , G. Oshanin , A. Sarracino , R. Voituriez

Bacterial processes ranging from gene expression to motility and biofilm formation are constantly challenged by internal and external noise. While the importance of stochastic fluctuations has been appreciated for chemotaxis, it is…

Biological Physics · Physics 2011-07-13 Knut Drescher , Jörn Dunkel , Luis H. Cisneros , Sujoy Ganguly , Raymond E. Goldstein

Flagellar-driven locomotion plays a critical role in bacterial attachment and colonization of surfaces, contributing to the risks of contamination and infection. Tremendous attempts to uncover the underlying principles governing bacterial…

Soft Condensed Matter · Physics 2025-02-19 Xin-Xin Xu , Yangguang Tian , Yuhe Pu , Bingchen Che , Hao Luo , Yanan Liu , Yan-Jun Liu , Guangyin Jing

We study the transport of bacteria in a porous media modeled by a square channel containing one cylindrical obstacle via molecular dynamics simulations coupled to a lattice Boltzmann fluid. Our bacteria model is a rod-shaped rigid body…

Soft Condensed Matter · Physics 2020-11-30 Miru Lee , Christoph Lohrmann , Kai Szuttor , Harold Auradou , Christian Holm

In natural environments, solid surfaces present both opportunities and challenges for bacteria. On one hand, they serve as platforms for biofilm formation, crucial for bacterial colonization and resilience in harsh conditions. On the other…

Biological Physics · Physics 2025-07-01 Antai Tao , Guangzhe Liu , Rongjing Zhang , Junhua Yuan

Cell invasion and spatial pattern formation are two distinct manifestations of cellular self-organisation in development, regeneration, and disease. Here, we develop and analyse a unified theoretical framework that links these two seemingly…

Tissues and Organs · Quantitative Biology 2026-04-30 Carles Falcó , Samuel W. S. Johnson , Mohit P. Dalwadi , Philip K. Maini

Monolayers of growing bacteria, confined within channel geometries, exhibit self-organization into a highly aligned laminar state along the axis of the channel. Although this phenomenon has been observed in experiments and simulations under…

Soft Condensed Matter · Physics 2024-11-04 Blake Langeslay , Will Fahy , Gabriel Juarez

Bacteria organize in a variety of collective states, from swarming, which has been attributed to rapid surface exploration, to biofilms, which are highly dense immobile communities attributed to stress resistance. It has been suggested that…

We study the partitioning of motile bacteria in an aqueous two-phase mixture of dextran (DEX) and polyethylene glycol (PEG), which can phase separate into DEX-rich and PEG-rich phases. While non-motile bacteria partition exclusively into…

Soft Condensed Matter · Physics 2024-12-23 Jiyong Cheon , Kyu Hwan Choi , Kevin J. Modica , Robert J. Mitchell , Sho C. Takatori , Joonwoo Jeong

Collective behavior of bacterial colonies plays critical roles in adaptability, survivability, biofilm expansion and infection. We employ an individual-based model of an interstitial biofilm to study emergent pattern formation based on the…

Adaptation and Self-Organizing Systems · Physics 2017-02-01 Cameron Zachreson , Christian Wolff , Cynthia B. Whitchurch , Milos Toth

We investigate the propagating profiles of a degenerate chemotaxis model describing the bacteria chemotaxis and consumption of oxygen by aerobic bacteria, in particular, the effect of the initial attractant distribution on bacterial…

Analysis of PDEs · Mathematics 2020-05-12 Tianyuan Xu , Shanming Ji , Ming Mei , Jingxue Yin

Complex spatial patterns in biological systems often arise through self-organization without a central coordination, guided by local interactions and chemical signaling. In this study, we explore how motility-dependent chemical deposition…

Biological Physics · Physics 2025-04-24 Subhashree Subhrasmita Khuntia , Debasish Chaudhuri , Abhishek Chaudhuri

Fluid flow has a major effect on the aggregation and fragmentation of bacterial colonies. Yet, a generic framework to understand and predict how hydrodynamics affects colony size remains elusive. This study investigates how fluid flow…

Soft Condensed Matter · Physics 2026-04-21 Yuri Z. Sinzato , Robert Uittenbogaard , Petra M. Visser , Jef Huisman , Maziyar Jalaal

In this paper we present a hydrodynamic approach to describe the motion of migrating bacteria as a special class of self-propelled systems. Analytical and numerical calculations has been performed to study the behavior of our model in the…

Soft Condensed Matter · Physics 2015-06-25 Zoltan Csahok , Andras Czirok

Bacterial biofilms are usually assumed to originate from individual cells deposited on a surface. However, many biofilm-forming bacteria tend to aggregate in the planktonic phase so that it is possible that many natural and infectious…

Anaerobic processes (e.g., methanogenesis and fermentation) largely contribute to element cycling and natural contaminant attenuation/mobilization, even in well-oxygenated porous environments, such as shallow aquifers. This paradox is…

Biological Physics · Physics 2022-11-24 Giulia Ceriotti , Sergey M. Borisov , Jasmine Berg , Pietro de Anna

Bacteria build multicellular communities termed biofilms, which are often encased in a self-secreted extracellular matrix that gives the community mechanical strength and protection against harsh chemicals. How bacteria assemble distinct…

Biological Physics · Physics 2023-09-27 Jakub A. Kochanowski , Bobby Carroll , Merrill E. Asp , Emma Kaputa , Alison E. Patteson

A diffusion-reaction model for the growth of bacterial colonies is presented. The often observed cooperative behavior developed by bacteria which increases their motility in adverse growth conditions is here introduced as a nonlinear…

Condensed Matter · Physics 2009-10-31 A. M. Lacasta , I. R. Cantalapiedra , C. E. Auguet , A. Penaranda , L. Ramirez-Piscina