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Real-world large-scale datasets are heteroskedastic and imbalanced -- labels have varying levels of uncertainty and label distributions are long-tailed. Heteroskedasticity and imbalance challenge deep learning algorithms due to the…
Hierarchical multi-label text classification (HMTC) has been gaining popularity in recent years thanks to its applicability to a plethora of real-world applications. The existing HMTC algorithms largely focus on the design of classifiers,…
Segmentation of objects of interest is one of the central tasks in medical image analysis, which is indispensable for quantitative analysis. When developing machine-learning based methods for automated segmentation, manual annotations are…
Uncertainty in machine learning models is a timely and vast field of research. In supervised learning, uncertainty can already occur in the first stage of the training process, the annotation phase. This scenario is particularly evident…
Nuclei segmentation is a crucial task for whole slide image analysis in digital pathology. Generally, the segmentation performance of fully-supervised learning heavily depends on the amount and quality of the annotated data. However, it is…
Large amounts of unlabelled data are commonplace for many applications in computational pathology, whereas labelled data is often expensive, both in time and cost, to acquire. We investigate the performance of unsupervised and supervised…
Despite that deep learning has achieved state-of-the-art performance for medical image segmentation, its success relies on a large set of manually annotated images for training that are expensive to acquire. In this paper, we propose an…
Assessing the presence of potentially malignant lymph nodes aids in estimating cancer progression, and identifying surrounding benign lymph nodes can assist in determining potential metastatic pathways for cancer. For quantitative analysis,…
Annotators exhibit disagreement during data labeling, which can be termed as annotator label uncertainty. Annotator label uncertainty manifests in variations of labeling quality. Training with a single low-quality annotation per sample…
Melanoma represents a critical health risk due to its aggressive progression and high mortality, underscoring the need for early, interpretable diagnostic tools. While deep learning has advanced in skin lesion classification, most existing…
Deep learning-based methods are gaining traction in digital pathology, with an increasing number of publications and challenges that aim at easing the work of systematically and exhaustively analyzing tissue slides. These methods often…
Semantic segmentation is a crucial task in biomedical image processing, which recent breakthroughs in deep learning have allowed to improve. However, deep learning methods in general are not yet widely used in practice since they require…
Training a neural network with a large labeled dataset is still a dominant paradigm in computational histopathology. However, obtaining such exhaustive manual annotations is often expensive, laborious, and prone to inter and Intra-observer…
Annotation scarcity has become a major obstacle for training powerful deep-learning models for medical image segmentation, restricting their deployment in clinical scenarios. To address it, semi-supervised learning by exploiting abundant…
Large scale image classification datasets often contain noisy labels. We take a principled probabilistic approach to modelling input-dependent, also known as heteroscedastic, label noise in these datasets. We place a multivariate Normal…
The success of deep learning methods in medical image segmentation tasks heavily depends on a large amount of labeled data to supervise the training. On the other hand, the annotation of biomedical images requires domain knowledge and can…
Annotation variability remains a substantial challenge in medical image segmentation, stemming from ambiguous imaging boundaries and diverse clinical expertise. Traditional deep learning methods producing single deterministic segmentation…
Segmentation of Prostate Cancer (PCa) tissues from Gleason graded histopathology images is vital for accurate diagnosis. Although deep learning (DL) based segmentation methods achieve state-of-the-art accuracy, they rely on large datasets…
Annotating large unlabeled datasets can be a major bottleneck for machine learning applications. We introduce a scheme for inferring labels of unlabeled data at a fraction of the cost of labeling the entire dataset. Our scheme, bounded…
Despite the remarkable performance of supervised medical image segmentation models, relying on a large amount of labeled data is impractical in real-world situations. Semi-supervised learning approaches aim to alleviate this challenge using…