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The AIED community envisions AI evolving "from tools to teammates," yet most research still examines AI agents primarily through one-on-one human-AI interactions. We provide an alternative perspective: a rapidly growing ecosystem of AI…

Computers and Society · Computer Science 2026-04-27 Eason Chen , Ce Guan , Zhonghao Zhao , Joshua Zekeri , Afeez Edeifo Shaibu , Emmanuel Osadebe Prince , Cyuan-Jhen Wu , A Elshafiey

Frontier scientific reasoning is rapidly emerging as a key foundation for advancing AI agents in automated scientific discovery. Deep research agents offer a promising approach to this challenge. These models develop robust problem-solving…

Artificial Intelligence · Computer Science 2026-05-27 Tianshi Zheng , Rui Wang , Xiyun Li , Kelvin Kiu Wai Tam , Newt Nguyen Kim Hue Nam , Wei Fan , Yangqiu Song , Tianqing Fang

Medical imaging research is increasingly shifting from controlled benchmark evaluation toward real-world clinical deployment. In such settings, applying analytical methods extends beyond model design to require dataset-aware workflow…

Recent advances in large language models have sparked growing interest in AI agents capable of solving complex, real-world tasks. However, most existing agent systems rely on manually crafted configurations that remain static after…

Artificial Intelligence · Computer Science 2025-09-03 Jinyuan Fang , Yanwen Peng , Xi Zhang , Yingxu Wang , Xinhao Yi , Guibin Zhang , Yi Xu , Bin Wu , Siwei Liu , Zihao Li , Zhaochun Ren , Nikos Aletras , Xi Wang , Han Zhou , Zaiqiao Meng

Artificial intelligence is reshaping scientific exploration, but most methods automate procedural tasks without engaging in scientific reasoning, limiting autonomy in discovery. We introduce Materials Agents for Simulation and Theory in…

The rapid development and adoption of Generative AI (GAI) technology in the form of chatbots such as ChatGPT and Claude has greatly increased interest in agentic machines. This paper introduces the Autonomous Cognitive Entity (ACE) model, a…

Human-Computer Interaction · Computer Science 2023-11-02 David Shapiro , Wangfan Li , Manuel Delaflor , Carlos Toxtli

Large language model (LLM)-based agents that reason, plan, and act through tools, memory, and structured interaction are emerging as a promising paradigm for automating complex workflows. Recent systems such as OpenClaw and Claude Code…

Information Retrieval · Computer Science 2026-05-27 Yingli Zhou , Wang Shu , Yaodong Su , Wenchuan Du , Yixiang Fang , Xuemin Lin

In this paper, we present AgentDisCo, a novel Disentangled and Collaborative agentic architecture that formulates deep research as an adversarial optimization problem between information exploration and exploitation. Unlike existing…

Information Retrieval · Computer Science 2026-05-13 Jiarui Jin , Zexuan Yan , Shijian Wang , Wenxiang Jiao , Yuan Lu

The advancement of data-driven materials science is currently constrained by a fundamental bottleneck: the vast majority of historical experimental data remains locked within the unstructured text and rasterized figures of legacy scientific…

Databases · Computer Science 2026-02-04 Yue Wu , Tianhao Su , Shunbo Hu , Deng Pan

The efficacy of AI agents in healthcare research is hindered by their reliance on static, predefined strategies. This creates a critical limitation: agents can become better tool-users but cannot learn to become better strategic planners, a…

Artificial Intelligence · Computer Science 2025-08-08 Huiya Zhao , Yinghao Zhu , Zixiang Wang , Yasha Wang , Junyi Gao , Liantao Ma

Recent work explores agentic inference-time techniques to perform structured, multi-step reasoning. However, stateless inference often struggles on multi-step tasks due to the absence of persistent state. Moreover, task-specific fine-tuning…

Machine Learning · Computer Science 2025-10-09 Arshika Lalan , Rajat Ghosh , Aditya Kolsur , Debojyoti Dutta

Autonomous agent frameworks still struggle to reconcile long-term experiential learning with real-time, context-sensitive decision-making. In practice, this gap appears as static cognition, rigid workflow dependence, and inefficient context…

Artificial Intelligence · Computer Science 2026-03-11 Xiaoxing Wang , Ning Liao , Shikun Wei , Chen Tang , Feiyu Xiong

Self++ is a design blueprint for human-AI symbiosis in extended reality (XR) that preserves human authorship while still benefiting from increasingly capable AI agents. Because XR can shape both perceptual evidence and action, apparently…

Human-Computer Interaction · Computer Science 2026-03-31 Thammathip Piumsomboon

Clinical image interpretation is inherently multi-step and tool-centric: clinicians iteratively combine visual evidence with patient context, quantify findings, and refine their decisions through a sequence of specialized procedures. While…

Artificial Intelligence · Computer Science 2026-03-09 Lin Fan , Pengyu Dai , Zhipeng Deng , Haolin Wang , Xun Gong , Yefeng Zheng , Yafei Ou

We introduce a novel large language model (LLM)-driven agent framework, which iteratively refines queries and filters contextual evidence by leveraging dynamically evolving knowledge. A defining feature of the system is its decoupling of…

Artificial Intelligence · Computer Science 2025-04-02 Seyoung Song

Autonomous agent frameworks built upon large language models (LLMs) are evolving into complex, tool-integrated, and continuously operating systems, introducing security risks beyond traditional prompt-level vulnerabilities. As this paradigm…

Cryptography and Security · Computer Science 2026-05-01 Luyao Xu , Xiang Chen

The rapid proliferation of scientific knowledge presents a grand challenge: transforming this vast repository of information into an active engine for discovery, especially in high-stakes domains like healthcare. Current AI agents, however,…

Artificial Intelligence · Computer Science 2025-10-14 Yinghao Zhu , Yifan Qi , Zixiang Wang , Lei Gu , Dehao Sui , Haoran Hu , Xichen Zhang , Ziyi He , Junjun He , Liantao Ma , Lequan Yu

As data continues to grow in scale and complexity, preparing, transforming, and analyzing it remains labor-intensive, repetitive, and difficult to scale. Since data contains knowledge and AI learns knowledge from it, the alignment between…

Artificial Intelligence · Computer Science 2025-10-07 Yanjie Fu , Dongjie Wang , Wangyang Ying , Xinyuan Wang , Xiangliang Zhang , Huan Liu , Jian Pei

Scientific discovery can be modeled as a sequence of probabilistic decisions that map physical problems to numerical solutions. Recent agentic AI systems automate individual scientific tasks by orchestrating LLM-driven planners, solvers,…

Machine Learning · Computer Science 2026-05-13 Juan Diego Toscano , Zhaojie Chai , George Em Karniadakis

As Large Language Models (LLMs) become ubiquitous across various scientific domains, their lack of ability to perform complex tasks like running simulations or to make complex decisions limits their utility. LLM-based agents bridge this gap…

Computation and Language · Computer Science 2026-01-21 Anurag Acharya , Timothy Vega , Rizwan A. Ashraf , Anshu Sharma , Derek Parker , Robert Rallo
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