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Fundus images are widely used for diagnosing various eye diseases, such as diabetic retinopathy, glaucoma, and age-related macular degeneration. However, manual analysis of fundus images is time-consuming and prone to errors. In this…
In this work, we propose a new paradigm of iterative model-based reconstruction algorithms for providing real-time solution for zooming-in and refining a region of interest in medical and clinical tomographic images. This algorithmic…
Gliomas are brain tumours with a high mortality rate. There are various grades and sub-types of this tumour, and the treatment procedure varies accordingly. Clinicians and oncologists diagnose and categorise these tumours based on visual…
Vascular structures in the retina contain important information for the detection and analysis of ocular diseases, including age-related macular degeneration, diabetic retinopathy and glaucoma. Commonly used modalities in diagnosis of these…
Deep learning models, such as the fully convolutional network (FCN), have been widely used in 3D biomedical segmentation and achieved state-of-the-art performance. Multiple modalities are often used for disease diagnosis and quantification.…
Effective feature fusion of multispectral images plays a crucial role in multi-spectral object detection. Previous studies have demonstrated the effectiveness of feature fusion using convolutional neural networks, but these methods are…
Previous approaches using deep learning algorithms to classify glaucomatous damage on fundus photographs have been limited by the requirement for human labeling of a reference training set. We propose a new approach using spectral-domain…
Current tomographic imaging systems need major improvements, especially when multi-dimensional, multi-scale, multi-temporal and multi-parametric phenomena are under investigation. Both preclinical and clinical imaging now depend on in vivo…
The Jaccard index, also known as Intersection-over-Union (IoU), is one of the most critical evaluation metrics in image semantic segmentation. However, direct optimization of IoU score is very difficult because the learning objective is…
The Segment Anything Model (SAM) has gained popularity as a versatile image segmentation method, thanks to its strong generalization capabilities across various domains. However, when applied to optic disc (OD) and optic cup (OC)…
Multimodal learning leverages complementary information derived from different modalities, thereby enhancing performance in medical image segmentation. However, prevailing multimodal learning methods heavily rely on extensive well-annotated…
Multimodal image registration (MIR) is a fundamental procedure in many image-guided therapies. Recently, unsupervised learning-based methods have demonstrated promising performance over accuracy and efficiency in deformable image…
Multi-modal medical image fusion is traditionally optimized for human visual perception, aiming to maximize generic contrast and structural fidelity. However, when these visually pleasing fused images are deployed in automated clinical…
Segmentation is vital for ophthalmology image analysis. But its various modal images hinder most of the existing segmentation algorithms applications, as they rely on training based on a large number of labels or hold weak generalization…
Automatic retinal layer segmentation with medical images, such as optical coherence tomography (OCT) images, serves as an important tool for diagnosing ophthalmic diseases. However, it is challenging to achieve accurate segmentation due to…
Gliomas are the most common primary tumors of the central nervous system. Multimodal MRI is widely used for the preliminary screening of gliomas and plays a crucial role in auxiliary diagnosis, therapeutic efficacy, and prognostic…
Multimodal large language models (MLLMs) hold promise for integrating diverse data modalities, but current medical adaptations such as LLaVA-Med often fail to fully exploit the synergy between color fundus photography (CFP) and optical…
As a representative optic degenerative condition, glaucoma has been a threat to millions due to its irreversibility and severe impact on human vision fields. Mainly characterized by dimmed and blurred visions, or peripheral vision loss,…
Medical image segmentation is a crucial method for assisting professionals in diagnosing various diseases through medical imaging. However, various factors such as noise, blurriness, and low contrast often hinder the accurate diagnosis of…
Medical image classification is a core task in computer-aided diagnosis (CAD), playing a pivotal role in early disease detection, treatment planning, and patient prognosis assessment. In ophthalmic practice, fluorescein fundus angiography…