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The proliferation of Large Language Models (LLMs) presents transformative potential for healthcare, yet practical deployment is hindered by the absence of frameworks that assess real-world clinical utility. Existing benchmarks test static…

The integration of Artificial Intelligence (AI), especially Large Language Models (LLMs), into the clinical diagnosis process offers significant potential to improve the efficiency and accessibility of medical care. While LLMs have shown…

Computation and Language · Computer Science 2024-10-15 Mingyu Derek Ma , Chenchen Ye , Yu Yan , Xiaoxuan Wang , Peipei Ping , Timothy S Chang , Wei Wang

Large language models (LLMs) have achieved strong performance on medical exam-style tasks, motivating growing interest in their deployment in real-world clinical settings. However, clinical decision-making is inherently safety-critical,…

Computation and Language · Computer Science 2026-04-13 Xiaohan Ren , Chenxiao Fan , Wenyin Ma , Hongliang He , Chongming Gao , Xiaoyan Zhao , Fuli Feng

In response to the pressing need for advanced clinical problem-solving tools in healthcare, we introduce BooksMed, a novel framework based on a Large Language Model (LLM). BooksMed uniquely emulates human cognitive processes to deliver…

Large language models (LLMs) have performed remarkably well in various natural language processing tasks by benchmarking, including in the Western medical domain. However, the professional evaluation benchmarks for LLMs have yet to be…

Computation and Language · Computer Science 2024-06-04 Wenjing Yue , Xiaoling Wang , Wei Zhu , Ming Guan , Huanran Zheng , Pengfei Wang , Changzhi Sun , Xin Ma

Large language models (LLMs) have attracted growing interest as supportive tools for psychiatric assessment and clinical decision support. However, existing mental health benchmarks largely rely on social media data or supportive dialogue…

Computation and Language · Computer Science 2026-05-19 Hoyun Song , Migyeong Kang , Jisu Shin , Jihyun Kim , Chanbi Park , Hangyeol Yoo , Jihyun An , Alice Oh , Jinyoung Han , KyungTae Lim

Large language models (LLMs) have demonstrated powerful text generation capabilities, bringing unprecedented innovation to the healthcare field. While LLMs hold immense promise for applications in healthcare, applying them to real clinical…

Computation and Language · Computer Science 2023-10-16 Rui Yang , Edison Marrese-Taylor , Yuhe Ke , Lechao Cheng , Qingyu Chen , Irene Li

As Large Language Model (LLM) alignment evolves from simple completions to complex, highly sophisticated generation, Reward Models are increasingly shifting toward rubric-guided evaluation to mitigate surface-level biases. However, the…

Artificial Intelligence · Computer Science 2026-03-04 Qiyuan Zhang , Junyi Zhou , Yufei Wang , Fuyuan Lyu , Yidong Ming , Can Xu , Qingfeng Sun , Kai Zheng , Peng Kang , Xue Liu , Chen Ma

In contrast to their remarkable performance on general knowledge QA, the true abilities of Large Language Models (LLMs) in tasks demanding deep, specialized reasoning, such as in protein biology, have yet to be thoroughly investigated.…

Quantitative Methods · Quantitative Biology 2025-12-30 Dingyi Rong , Zijian Chen , Qi Jia , Kaiwei Zhang , Haotian Lu , Guangtao Zhai , Ning Liu

As large language models (LLMs) develop increasingly sophisticated capabilities and find applications in medical settings, it becomes important to assess their medical safety due to their far-reaching implications for personal and public…

Artificial Intelligence · Computer Science 2024-10-11 Tessa Han , Aounon Kumar , Chirag Agarwal , Himabindu Lakkaraju

Evaluating large language models (LLMs) on open-ended questions is difficult because response quality depends on the question's context. Binary scores and static rubrics fail to capture these context-dependent requirements. Existing methods…

Computation and Language · Computer Science 2026-03-26 Shanghua Gao , Yuchang Su , Pengwei Sui , Curtis Ginder , Marinka Zitnik

Large Language Models (LLMs) are increasingly being explored for clinical question answering and decision support, yet safe deployment critically requires reliable handling of patient measurements in heterogeneous clinical notes. Existing…

Computation and Language · Computer Science 2026-04-16 Minh-Vuong Nguyen , Fatemeh Shiri , Zhuang Li , Karin Verspoor

LLM development has aroused great interest in Sequential Recommendation (SR) applications. However, comprehensive evaluation of SR models remains lacking due to the limitations of the existing benchmarks: 1) an overemphasis on accuracy,…

Information Retrieval · Computer Science 2026-04-14 Jianhong Li , Zeheng Qian , Wangze Ni , Haoyang Li , Hongwei Yao , Yang Bai , Kui Ren

With the rapid development of large language models (LLMs), assessing their performance on health-related inquiries has become increasingly essential. The use of these models in real-world contexts-where misinformation can lead to serious…

Computation and Language · Computer Science 2025-02-24 Chenlu Guo , Nuo Xu , Yi Chang , Yuan Wu

Large Language Models (LLMs) constitute a breakthrough state-of-the-art Artificial Intelligence (AI) technology which is rapidly evolving and promises to aid in medical diagnosis either by assisting doctors or by simulating a doctor's…

Recently, there has been a growing interest among large language model (LLM) developers in LLM-based document reading systems, which enable users to upload their own documents and pose questions related to the document contents, going…

Computation and Language · Computer Science 2024-07-16 Anni Zou , Wenhao Yu , Hongming Zhang , Kaixin Ma , Deng Cai , Zhuosheng Zhang , Hai Zhao , Dong Yu

The mismatch between the growing demand for psychological counseling and the limited availability of services has motivated research into the application of Large Language Models (LLMs) in this domain. Consequently, there is a need for a…

Computation and Language · Computer Science 2025-11-13 Bichen Wang , Yixin Sun , Junzhe Wang , Hao Yang , Xing Fu , Yanyan Zhao , Si Wei , Shijin Wang , Bing Qin

The adeptness of Large Language Models (LLMs) in comprehending and following natural language instructions is critical for their deployment in sophisticated real-world applications. Existing evaluations mainly focus on fragmented…

Computation and Language · Computer Science 2025-05-07 Tao Zhang , Chenglin Zhu , Yanjun Shen , Wenjing Luo , Yan Zhang , Hao Liang , Tao Zhang , Fan Yang , Mingan Lin , Yujing Qiao , Weipeng Chen , Bin Cui , Wentao Zhang , Zenan Zhou

Large language models (LLMs) have shown significant promise across various medical applications, with ophthalmology being a notable area of focus. Many ophthalmic tasks have shown substantial improvement through the integration of LLMs.…

Computation and Language · Computer Science 2025-02-04 Chengfeng Zhou , Ji Wang , Juanjuan Qin , Yining Wang , Ling Sun , Weiwei Dai

The rapid advancement of large language models (LLMs) has accelerated their integration into clinical decision support, particularly in prescription review. To enable systematic and fine-grained evaluation, we developed RxBench, a…

Computation and Language · Computer Science 2025-12-03 Yan Yang , Mouxiao Bian , Peiling Li , Bingjian Wen , Ruiyao Chen , Kangkun Mao , Xiaojun Ye , Tianbin Li , Pengcheng Chen , Bing Han , Jie Xu , Kaifeng Qiu , Junyan Wu