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Medical image segmentation is inherently uncertain. For a given image, there may be multiple plausible segmentation hypotheses, and physicians will often disagree on lesion and organ boundaries. To be suited to real-world application,…

Computer Vision and Pattern Recognition · Computer Science 2021-09-28 João Lourenço Silva , Arlindo L. Oliveira

Medical image segmentation is critical for disease diagnosis and treatment assessment. However, concerns regarding the reliability of segmentation regions persist among clinicians, mainly attributed to the absence of confidence assessment,…

Image and Video Processing · Electrical Eng. & Systems 2025-09-12 Ke Zou , Yidi Chen , Ling Huang , Xuedong Yuan , Xiaojing Shen , Meng Wang , Rick Siow Mong Goh , Yong Liu , Huazhu Fu

The recent Segment Anything Models (SAMs) have emerged as foundational visual models for general interactive segmentation. Despite demonstrating robust generalization abilities, they still suffer performance degradations in scenarios…

Computer Vision and Pattern Recognition · Computer Science 2025-02-17 Yuan Yao , Qiushi Yang , Miaomiao Cui , Liefeng Bo

Segmentation is vital for ophthalmology image analysis. But its various modal images hinder most of the existing segmentation algorithms applications, as they rely on training based on a large number of labels or hold weak generalization…

Computer Vision and Pattern Recognition · Computer Science 2023-04-27 Zhongxi Qiu , Yan Hu , Heng Li , Jiang Liu

Few-shot segmentation is the problem of learning to identify specific types of objects (e.g., airplanes) in images from a small set of labeled reference images. The current state of the art is driven by resource-intensive construction of…

Computer Vision and Pattern Recognition · Computer Science 2024-12-17 Savinay Nagendra , Kashif Rashid , Chaopeng Shen , Daniel Kifer

Semi-supervised image segmentation has attracted great attention recently. The key is how to leverage unlabeled images in the training process. Most methods maintain consistent predictions of the unlabeled images under variations (e.g.,…

Computer Vision and Pattern Recognition · Computer Science 2024-03-28 Yuliang Gu , Zhichao Sun , Tian Chen , Xin Xiao , Yepeng Liu , Yongchao Xu , Laurent Najman

Robust and accurate segmentation of scenes has become one core functionality in various visual recognition and navigation tasks. This has inspired the recent development of Segment Anything Model (SAM), a foundation model for general mask…

Computer Vision and Pattern Recognition · Computer Science 2024-08-20 Aoran Xiao , Weihao Xuan , Heli Qi , Yun Xing , Naoto Yokoya , Shijian Lu

The Segment Anything Model (SAM) has drawn significant attention from researchers who work on medical image segmentation because of its generalizability. However, researchers have found that SAM may have limited performance on medical…

Computer Vision and Pattern Recognition · Computer Science 2024-03-28 Yihao Liu , Jiaming Zhang , Andres Diaz-Pinto , Haowei Li , Alejandro Martin-Gomez , Amir Kheradmand , Mehran Armand

Image segmentation foundation models (SFMs) like Segment Anything Model (SAM) have achieved impressive zero-shot and interactive segmentation across diverse domains. However, they struggle to segment objects with certain structures,…

Computer Vision and Pattern Recognition · Computer Science 2025-11-17 Yixin Zhang , Nicholas Konz , Kevin Kramer , Maciej A. Mazurowski

The Segment Anything Model (SAM) is the first foundation model for general image segmentation. It has achieved impressive results on various natural image segmentation tasks. However, medical image segmentation (MIS) is more challenging…

Image and Video Processing · Electrical Eng. & Systems 2024-01-18 Yuhao Huang , Xin Yang , Lian Liu , Han Zhou , Ao Chang , Xinrui Zhou , Rusi Chen , Junxuan Yu , Jiongquan Chen , Chaoyu Chen , Sijing Liu , Haozhe Chi , Xindi Hu , Kejuan Yue , Lei Li , Vicente Grau , Deng-Ping Fan , Fajin Dong , Dong Ni

The recently released Segment Anything Model (SAM) has shown powerful zero-shot segmentation capabilities through a semi-automatic annotation setup in which the user can provide a prompt in the form of clicks or bounding boxes. There is…

Computer Vision and Pattern Recognition · Computer Science 2024-06-04 Benjamin Towle , Xin Chen , Ke Zhou

Segment Anything Model (SAM) fine-tuning has shown remarkable performance in medical image segmentation in a fully supervised manner, but requires precise annotations. To reduce the annotation cost and maintain satisfactory performance, in…

Computer Vision and Pattern Recognition · Computer Science 2025-01-22 Shumeng Li , Lei Qi , Qian Yu , Jing Huo , Yinghuan Shi , Yang Gao

Scientific Artificial Intelligence (AI) applications require models that deliver trustworthy uncertainty estimates while respecting domain constraints. Existing uncertainty quantification methods lack mechanisms to incorporate symbolic…

Machine Learning · Computer Science 2026-01-21 Shahnawaz Alam , Mohammed Mudassir Uddin , Mohammed Kaif Pasha

Medical image segmentation is clinically important, yet data privacy and the cost of expert annotation limit the availability of labeled data. Federated semi-supervised learning (FSSL) offers a solution but faces two challenges:…

Computer Vision and Pattern Recognition · Computer Science 2025-11-19 Sahar Nasirihaghighi , Negin Ghamsarian , Yiping Li , Marcel Breeuwer , Raphael Sznitman , Klaus Schoeffmann

Deformable registration is a fundamental task in medical image processing, aiming to achieve precise alignment by establishing nonlinear correspondences between images. Traditional methods offer good adaptability and interpretability but…

Computer Vision and Pattern Recognition · Computer Science 2025-05-13 Jing Hu , Kaiwei Yu , Hongjiang Xian , Shu Hu , Xin Wang

This paper presents a novel unsupervised domain adaptation framework, called Synergistic Image and Feature Adaptation (SIFA), to effectively tackle the problem of domain shift. Domain adaptation has become an important and hot topic in…

Computer Vision and Pattern Recognition · Computer Science 2019-06-19 Cheng Chen , Qi Dou , Hao Chen , Jing Qin , Pheng-Ann Heng

Medical image segmentation has immense clinical applicability but remains a challenge despite advancements in deep learning. The Segment Anything Model (SAM) exhibits potential in this field, yet the requirement for expertise intervention…

Computer Vision and Pattern Recognition · Computer Science 2023-11-14 Yinsong Xu , Jiaqi Tang , Aidong Men , Qingchao Chen

Segmentation is an important analysis task for biomedical images, enabling the study of individual organelles, cells or organs. Deep learning has massively improved segmentation methods, but challenges remain in generalization to new…

Computer Vision and Pattern Recognition · Computer Science 2025-06-03 Carolin Teuber , Anwai Archit , Constantin Pape

The segmentation foundation model, e.g., Segment Anything Model (SAM), has attracted increasing interest in the medical image community. Early pioneering studies primarily concentrated on assessing and improving SAM's performance from the…

Image and Video Processing · Electrical Eng. & Systems 2024-06-19 Qin Li , Yizhe Zhang , Yan Li , Jun Lyu , Meng Liu , Longyu Sun , Mengting Sun , Qirong Li , Wenyue Mao , Xinran Wu , Yajing Zhang , Yinghua Chu , Shuo Wang , Chengyan Wang

Foundation models are experiencing a surge in popularity. The Segment Anything model (SAM) asserts an ability to segment a wide spectrum of objects but required supervised training at unprecedented scale. We compared SAM's performance…

Image and Video Processing · Electrical Eng. & Systems 2025-03-11 Danielle Ferreira , Rima Arnaout