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Efficient error-controlled lossy compressors are becoming critical to the success of today's large-scale scientific applications because of the ever-increasing volume of data produced by the applications. In the past decade, many lossless…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-11-04 Kai Zhao , Sheng Di , Xin Liang , Sihuan Li , Dingwen Tao , Julie Bessac , Zizhong Chen , Franck Cappello

Structure-based protein design has attracted increasing interest, with numerous methods being introduced in recent years. However, a universally accepted method for evaluation has not been established, since the wet-lab validation can be…

Quantitative Methods · Quantitative Biology 2023-12-04 Chuanrui Wang , Bozitao Zhong , Zuobai Zhang , Narendra Chaudhary , Sanchit Misra , Jian Tang

The design of low-power wearables for the biomedical domain has received a lot of attention in recent decades, as technological advances in chip manufacturing have allowed real-time monitoring of patients using low-complexity ML within the…

As automated attack techniques rapidly advance, CAPTCHAs remain a critical defense mechanism against malicious bots. However, existing CAPTCHA schemes encompass a diverse range of modalities -- from static distorted text and obfuscated…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Zonglin Wu , Yule Xue , Yaoyao Feng , Xiaolong Wang , Yiren Song

Over the last few years, Large Language Models (LLMs) have emerged as a valuable tool for Electronic Design Automation (EDA). State-of-the-art research in LLM-aided design has demonstrated the ability of LLMs to generate syntactically…

Hardware Architecture · Computer Science 2025-07-10 Elisavet Lydia Alvanaki , Kevin Lee , Luca P. Carloni

Commonsense question-answering (QA) tasks, in the form of benchmarks, are constantly being introduced for challenging and comparing commonsense QA systems. The benchmarks provide question sets that systems' developers can use to train and…

Artificial Intelligence · Computer Science 2020-12-23 Henrique Santos , Minor Gordon , Zhicheng Liang , Gretchen Forbush , Deborah L. McGuinness

Patent retrieval underpins critical decisions in innovation, examination, and IP strategy, yet progress has been hampered by the absence of benchmarks that reflect the diversity of real world search scenarios. We address this gap with two…

Information Retrieval · Computer Science 2026-04-28 Younes Djemmal , You Zuo , Kim Gerdes , Kirian Guiller

Computational antibody design seeks to automatically create an antibody that binds to an antigen. The binding affinity is governed by the 3D binding interface where antibody residues (paratope) closely interact with antigen residues…

Biomolecules · Quantitative Biology 2022-07-15 Wengong Jin , Regina Barzilay , Tommi Jaakkola

Large language models (LLMs) are adopted for software and hardware design, yet these domains are still evaluated separately. Software benchmarks typically assume fixed hardware targets, while hardware benchmarks focus on component-level…

Hardware Architecture · Computer Science 2026-05-20 Pei-Huan Tsai , Kuan-Lin Chiu , William Baisi , Pin-Yu Chen , Luca P. Carloni

Learning multimodal representations involves integrating information from multiple heterogeneous sources of data. It is a challenging yet crucial area with numerous real-world applications in multimedia, affective computing, robotics,…

Progress in a research field can be hard to assess, in particular when many concurrent methods are proposed in a short period of time. This is the case in digital pathology, where many foundation models have been released recently to serve…

Computer Vision and Pattern Recognition · Computer Science 2026-02-18 Pierre Marza , Leo Fillioux , Sofiène Boutaj , Kunal Mahatha , Christian Desrosiers , Pablo Piantanida , Jose Dolz , Stergios Christodoulidis , Maria Vakalopoulou

Several fundamental changes in technology indicate domain-specific hardware and software co-design is the only path left. In this context, architecture, system, data management, and machine learning communities pay greater attention to…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-11-26 Wanling Gao , Jianfeng Zhan , Lei Wang , Chunjie Luo , Daoyi Zheng , Xu Wen , Rui Ren , Chen Zheng , Xiwen He , Hainan Ye , Haoning Tang , Zheng Cao , Shujie Zhang , Jiahui Dai

Processor chip design technology serves as a key frontier driving breakthroughs in computer science and related fields. With the rapid advancement of information technology, conventional design paradigms face three major challenges: the…

Although multimodal fusion has made significant progress, its advancement is severely hindered by the lack of adequate evaluation benchmarks. Current fusion methods are typically evaluated on a small selection of public datasets, a limited…

Machine Learning · Computer Science 2026-05-07 Leyan Xue , Changqing Zhang , Kecheng Xue , Xiaohong Liu , Guangyu Wang , Zongbo Han

Equation discovery from data is a central challenge in machine learning for science, which requires the recovery of concise symbolic expressions that govern complex physical and geometric phenomena. Recent large language model (LLM)…

Machine Learning · Computer Science 2026-03-04 Sanchit Kabra , Shobhnik Kriplani , Parshin Shojaee , Chandan K. Reddy

Large Language Models (LLMs) have made significant strides in front-end code generation. However, existing benchmarks exhibit several critical limitations: many tasks are overly simplistic, test cases often lack rigor, and end-to-end…

Software Engineering · Computer Science 2025-06-19 Hongda Zhu , Yiwen Zhang , Bing Zhao , Jingzhe Ding , Siyao Liu , Tong Liu , Dandan Wang , Yanan Liu , Zhaojian Li

Biomedical datasets are often constrained by stringent privacy requirements and frequently suffer from severe class imbalance. These two aspects hinder the development of accurate machine learning models. While generative AI offers a…

Computer Vision and Pattern Recognition · Computer Science 2025-09-03 Jan Carreras Boada , Rao Muhammad Umer , Carsten Marr

With the increasing prevalence of chiplet systems in high-performance computing applications, the number of design options has increased dramatically. Instead of chips defaulting to a single die design, now there are options for 2.5D and 3D…

Hardware Architecture · Computer Science 2025-03-21 Alexander Graening , Jonti Talukdar , Saptadeep Pal , Krishnendu Chakrabarty , Puneet Gupta

There is no consensus in the field of synthetic data on concise metrics for quality evaluations or benchmarks on large health datasets, such as historical epidemiological data. This study presents an evaluation of seven recent models from…

Machine Learning · Computer Science 2026-04-20 Jean-Baptiste Escudié , Benjamin Barnes , Stefan Meisegeier , Klaus Kraywinkel , Fabian Prasser , Nils Körber

Evaluating models on large benchmarks is very resource-intensive, especially during the period of rapid model evolution. Existing efficient evaluation methods estimate the performance of target models by testing them only on a small and…

Machine Learning · Computer Science 2025-06-03 Peiwen Yuan , Yueqi Zhang , Shaoxiong Feng , Yiwei Li , Xinglin Wang , Jiayi Shi , Chuyi Tan , Boyuan Pan , Yao Hu , Kan Li