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Large Language Models (LLMs) are increasingly applied in healthcare, yet ensuring their ethical integrity and safety compliance remains a major barrier to clinical deployment. This work introduces a multi-agent refinement framework designed…

Navigating healthcare systems can be complex and overwhelming, creating barriers for patients seeking timely and appropriate medical attention. In this paper, we introduce C-PATH (Conversational Patient Assistance and Triage in Healthcare),…

Computation and Language · Computer Science 2025-06-10 Qi Shi , Qiwei Han , Cláudia Soares

Large Language Models (LLMs) have demonstrated impressive capabilities across various specialist domains and have been integrated into high-stakes areas such as medicine. However, as existing medical-related benchmarks rarely stress-test…

Computation and Language · Computer Science 2026-03-26 Lin Yang , Yuancheng Yang , Xu Wang , Changkun Liu , Haihua Yang

Large Language Models (LLMs) are increasingly developed for use in complex professional domains, yet little is known about how teams design and evaluate these systems in practice. This paper examines the challenges and trade-offs in LLM…

Human-Computer Interaction · Computer Science 2026-02-17 Annalisa Szymanski , Oghenemaro Anuyah , Toby Jia-Jun Li , Ronald A. Metoyer

This paper explores the significant impact of AI-based medical devices, including wearables, telemedicine, large language models, and digital twins, on clinical decision support systems. It emphasizes the importance of producing outcomes…

Artificial Intelligence · Computer Science 2024-04-11 Elham Nasarian , Roohallah Alizadehsani , U. Rajendra Acharya , Kwok-Leung Tsui

Mobile and wearable healthcare monitoring play a vital role in facilitating timely interventions, managing chronic health conditions, and ultimately improving individuals' quality of life. Previous studies on large language models (LLMs)…

Artificial Intelligence · Computer Science 2025-10-01 Xin Wang , Ting Dang , Xinyu Zhang , Vassilis Kostakos , Michael J. Witbrock , Hong Jia

Diagnostic errors in healthcare persist as a critical challenge, with increasing numbers of patients turning to online resources for health information. While AI-powered healthcare chatbots show promise, there exists no standardized and…

Artificial Intelligence · Computer Science 2024-12-18 Deep Bhatt , Surya Ayyagari , Anuruddh Mishra

The rapid proliferation of large language models (LLMs) in healthcare creates an urgent need for scalable and psychometrically sound evaluation methods. Conventional static benchmarks are costly to administer repeatedly, vulnerable to data…

Computation and Language · Computer Science 2026-03-26 Tianpeng Zheng , Zhehan Jiang , Jiayi Liu , Shicong Feng

Low technology and eHealth literacy among older adults in retirement communities hinder engagement with digital tools. To address this, we designed an LLM-powered chatbot prototype using a human-centered approach for a local retirement…

Human-Computer Interaction · Computer Science 2025-04-29 Luna Xingyu Li , Ray-yuan Chung , Feng Chen , Wenyu Zeng , Yein Jeon , Oleg Zaslavsky

Conversational AI chatbots have become increasingly common within the customer service industry. Despite improvements in their emotional development, they often lack the authenticity of real customer service interactions or the competence…

Human-Computer Interaction · Computer Science 2025-02-14 Antonin Brun , Ruying Liu , Aryan Shukla , Frances Watson , Jonathan Gratch

With the rapid development of large language models (LLMs), assessing their performance on health-related inquiries has become increasingly essential. The use of these models in real-world contexts-where misinformation can lead to serious…

Computation and Language · Computer Science 2025-02-24 Chenlu Guo , Nuo Xu , Yi Chang , Yuan Wu

The rise of large language models (LLMs) has transformed healthcare by offering clinical guidance, yet their direct deployment to patients poses safety risks due to limited domain expertise. To mitigate this, we propose repositioning LLMs…

Computation and Language · Computer Science 2025-10-14 Wenya Xie , Qingying Xiao , Yu Zheng , Xidong Wang , Junying Chen , Ke Ji , Anningzhe Gao , Prayag Tiwari , Xiang Wan , Feng Jiang , Benyou Wang

Ramaswamy et al. reported in Nature Medicine that ChatGPT Health under-triages 51.6% of emergencies, concluding that consumer-facing AI triage poses safety risks. However, their evaluation used an exam-style protocol -- forced A/B/C/D…

Human-Computer Interaction · Computer Science 2026-03-27 David Fraile Navarro , Farah Magrabi , Enrico Coiera

The use of chatbots has spread, generating great interest in the industry for the possibility of automating tasks within the execution of their processes. The implementation of chatbots, however simple, is a complex endeavor that involves…

Software Engineering · Computer Science 2021-09-03 Bedilia Estrada-Torres , Adela del-Río-Ortega , Manuel Resinas

Most existing medical dialogue systems operate in a single-turn question--answering paradigm or rely on template-based datasets, limiting conversational realism and multilingual applicability. We introduce IndicMedDialog, a parallel…

Computation and Language · Computer Science 2026-05-14 Shubham Kumar Nigam , Suparnojit Sarkar , Piyush Patel

Evaluating large language models (LLMs) is challenging. Traditional ground-truth-based benchmarks fail to capture the comprehensiveness and nuance of real-world queries, while LLM-as-judge benchmarks suffer from grading biases and limited…

Computation and Language · Computer Science 2024-10-15 Jinjie Ni , Fuzhao Xue , Xiang Yue , Yuntian Deng , Mahir Shah , Kabir Jain , Graham Neubig , Yang You

Trustworthiness in healthcare question-answering (QA) systems is important for ensuring patient safety, clinical effectiveness, and user confidence. As large language models (LLMs) become increasingly integrated into medical settings, the…

Computation and Language · Computer Science 2025-11-04 Yinuo Wang , Baiyang Wang , Robert E. Mercer , Frank Rudzicz , Sudipta Singha Roy , Pengjie Ren , Zhumin Chen , Xindi Wang

This full research-to-practice paper explores approaches for developing course chatbots by comparing low-code platforms and custom-coded solutions in educational contexts. With the rise of Large Language Models (LLMs) like GPT-4 and LLaMA,…

Human-Computer Interaction · Computer Science 2025-09-18 Hemil Mehta , Tanvi Raut , Kohav Yadav , Edward F. Gehringer

Evaluating Large Language Models (LLMs) for mental health support is challenging due to the emotionally and cognitively complex nature of therapeutic dialogue. Existing benchmarks are limited in scale, reliability, often relying on…

Clinical reasoning in medicine is a hypothesis-driven process where physicians refine diagnoses from limited information through targeted history, physical examination, and diagnostic investigations. In contrast, current medical benchmarks…

Machine Learning · Computer Science 2025-10-14 Christopher Chiu , Silviu Pitis , Mihaela van der Schaar