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As high-throughput biological sequencing becomes faster and cheaper, the need to extract useful information from sequencing becomes ever more paramount, often limited by low-throughput experimental characterizations. For proteins, accurate…

Quantitative Methods · Quantitative Biology 2017-01-31 Xueliang Liu

Referring Expression Comprehension (REC) is a foundational cross-modal task that evaluates the interplay of language understanding, image comprehension, and language-to-image grounding. It serves as an essential testing ground for…

Computer Vision and Pattern Recognition · Computer Science 2025-06-16 Xuzheng Yang , Junzhuo Liu , Peng Wang , Guoqing Wang , Yang Yang , Heng Tao Shen

Grammatical Error Correction (GEC) faces a critical challenge concerning explainability, notably when GEC systems are designed for language learners. Existing research predominantly focuses on explaining grammatical errors extracted in…

Computation and Language · Computer Science 2025-02-24 Jingheng Ye , Shang Qin , Yinghui Li , Hai-Tao Zheng , Shen Wang , Qingsong Wen

Discovering the intended items of user queries from a massive repository of items is one of the main goals of an e-commerce search system. Relevance prediction is essential to the search system since it helps improve performance. When…

Information Retrieval · Computer Science 2023-07-21 Jiong Cai , Yong Jiang , Yue Zhang , Chengyue Jiang , Ke Yu , Jianhui Ji , Rong Xiao , Haihong Tang , Tao Wang , Zhongqiang Huang , Pengjun Xie , Fei Huang , Kewei Tu

Video Referring Expression Comprehension (REC) aims to localize a target object in video frames referred by the natural language expression. Recently, the Transformerbased methods have greatly boosted the performance limit. However, we…

Computer Vision and Pattern Recognition · Computer Science 2022-10-07 Ji Jiang , Meng Cao , Tengtao Song , Yuexian Zou

The task of Named Entity Recognition (NER) is an important component of many natural language processing systems, such as relation extraction and knowledge graph construction. In this work, we present a simple and effective approach for…

Computation and Language · Computer Science 2022-03-29 Urchade Zaratiana , Pierre Holat , Nadi Tomeh , Thierry Charnois

Machine Learning-guided solutions for protein learning tasks have made significant headway in recent years. However, success in scientific discovery tasks is limited by the accessibility of well-defined and labeled in-domain data. To tackle…

Machine Learning · Computer Science 2023-01-06 Ria Vinod , Pin-Yu Chen , Payel Das

We apply a general recurrent neural network (RNN) encoder framework to community question answering (cQA) tasks. Our approach does not rely on any linguistic processing, and can be applied to different languages or domains. Further…

Computation and Language · Computer Science 2016-03-24 Wei-Ning Hsu , Yu Zhang , James Glass

Deep learning models have driven significant progress in predicting protein function and interactions at the protein level. While these advancements have been invaluable for many biological applications such as enzyme engineering and…

Machine Learning · Computer Science 2025-05-20 Yang Tan , Wenrui Gou , Bozitao Zhong , Liang Hong , Huiqun Yu , Bingxin Zhou

We introduce a novel and efficient method for Event Coreference Resolution (ECR) applied to a lower-resourced language domain. By framing ECR as a graph reconstruction task, we are able to combine deep semantic embeddings with structural…

Computation and Language · Computer Science 2023-10-19 Loic De Langhe , Orphée De Clercq , Veronique Hoste

Mathematical Expression Recognition (MER) has made significant progress in recognizing simple expressions, but the robust recognition of complex mathematical expressions with many tokens and multiple lines remains a formidable challenge. In…

Computer Vision and Pattern Recognition · Computer Science 2025-12-17 Weikang Bai , Yongkun Du , Yuchen Su , Yazhen Xie , Zhineng Chen

Facial expressions play a crucial role in human communication serving as a powerful and impactful means to express a wide range of emotions. With advancements in artificial intelligence and computer vision, deep neural networks have emerged…

Computer Vision and Pattern Recognition · Computer Science 2025-01-15 Yassine El Boudouri , Amine Bohi

State-of-the-art neural models typically encode document-query pairs using cross-attention for re-ranking. To this end, models generally utilize an encoder-only (like BERT) paradigm or an encoder-decoder (like T5) approach. These paradigms,…

Computation and Language · Computer Science 2022-04-26 Kai Hui , Honglei Zhuang , Tao Chen , Zhen Qin , Jing Lu , Dara Bahri , Ji Ma , Jai Prakash Gupta , Cicero Nogueira dos Santos , Yi Tay , Don Metzler

Understanding how the brain responds to sensory inputs is challenging: brain recordings are partial, noisy, and high dimensional; they vary across sessions and subjects and they capture highly nonlinear dynamics. These challenges have led…

Neurons and Cognition · Quantitative Biology 2022-10-03 Omar Chehab , Alexandre Defossez , Jean-Christophe Loiseau , Alexandre Gramfort , Jean-Remi King

Large Language Models (LLMs) often fail to utilize their latent reasoning capabilities due to a distributional mismatch between ambiguous human inquiries and the structured logic required for machine activation. Existing alignment methods…

Computation and Language · Computer Science 2026-04-29 Yixiao Zhou , Dongzhou Cheng , zhiliang wu , Yi Yang , Yu Cheng , Hehe Fan

Protein function annotation is an important yet challenging task in biology. Recent deep learning advancements show significant potential for accurate function prediction by learning from protein sequences and structures. Nevertheless,…

Biomolecules · Quantitative Biology 2024-02-14 Zuobai Zhang , Jiarui Lu , Vijil Chenthamarakshan , Aurélie Lozano , Payel Das , Jian Tang

Pretrained using large amount of data, autoregressive language models are able to generate high quality sequences. However, these models do not perform well under hard lexical constraints as they lack fine control of content generation…

Computation and Language · Computer Science 2021-03-18 Lee-Hsun Hsieh , Yang-Yin Lee , Ee-Peng Lim

Identifying enzymes that catalyze target biochemical reactions is a key step in computational enzyme discovery and biocatalyst design. Recent representation-learning methods formulate this problem as enzyme--reaction matching, where paired…

Biomolecules · Quantitative Biology 2026-05-26 Gengmo Zhou , Feng Yu , Wenda Wang , Zhifeng Gao , Guolin Ke , Zhewei Wei , Zhen Wang

Predicting enzyme-substrate interactions has long been a fundamental problem in biochemistry and metabolic engineering. While existing methods could leverage databases of expert-curated enzyme-substrate pairs for models to learn from known…

Artificial Intelligence · Computer Science 2026-01-12 Tengwei Song , Long Yin , Zhen Han , Zhiqiang Xu

We treat grammatical error correction (GEC) as a classification problem in this study, where for different types of errors, a target word is identified, and the classifier predicts the correct word form from a set of possible choices. We…

Computation and Language · Computer Science 2018-07-03 Zhu Kaili , Chuan Wang , Ruobing Li , Yang Liu , Tianlei Hu , Hui Lin