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We employ uncertain parametric CTMCs with parametric transition rates and a prior on the parameter values. The prior encodes uncertainty about the actual transition rates, while the parameters allow dependencies between transition rates.…

Logic in Computer Science · Computer Science 2022-12-08 Thom S. Badings , Nils Jansen , Sebastian Junges , Marielle Stoelinga , Matthias Volk

Not only does mobile health technology enable researchers to track changes in multiple longitudinal outcomes of interest and to record the occurrence of health-related events over time, but it also allows for the delivery of repeated…

Covariate adjustment is a widely used technique in randomized clinical trials (RCTs) for improving the efficiency of treatment effect estimators. By adjusting for predictive baseline covariates, variance can be reduced, enhancing…

Methodology · Statistics 2025-10-16 Mathias Lerbech Jeppesen , Emilie Højbjerre-Frandsen

In recent studies on model-based reinforcement learning (MBRL), incorporating uncertainty in forward dynamics is a state-of-the-art strategy to enhance learning performance, making MBRLs competitive to cutting-edge model free methods,…

Machine Learning · Computer Science 2019-10-08 Masashi Okada , Tadahiro Taniguchi

Randomized controlled trials (RCTs) provide strong internal validity compared with observational studies. However, selection bias threatens the external validity of randomized trials. Thus, RCT results may not apply to either broad public…

Methodology · Statistics 2017-04-26 Ziyue Chen , Eloise Kaizar

In this paper, I propose a general algorithm for multiple change point analysis via multivariate distribution-free nonparametric testing based on the concept of ranks that are defined by measure transportation. Multivariate ranks and the…

Methodology · Statistics 2021-11-09 Amanda Ng

Randomized control trials (RCTs) are the gold standard for estimating causal effects, but often use samples that are non-representative of the actual population of interest. We propose a reweighting method for estimating population average…

Methodology · Statistics 2022-02-09 Kellie Ottoboni , Jason Poulos

Often in Phase 3 clinical trials measuring a long-term time-to-event endpoint, such as overall survival or progression-free survival, investigators also collect repeated measures on biomarkers which may be predictive of the primary…

Methodology · Statistics 2022-11-30 Abigail J. Burdon , Lisa V. Hampson , Christopher Jennison

Neurodegenerative diseases such as Alzheimer's and Parkinson's often exhibit complex, multivariate longitudinal outcomes that require advanced statistical methods to comprehensively evaluate treatment efficacy. The Longitudinal Rank Sum…

Methodology · Statistics 2025-02-12 Dhrubajyoti Ghosh , Xiaoming Xu , Sheng Luo

In this paper, we develop a semiparametric sensitivity analysis approach designed to address unmeasured confounding in observational studies with time-to-event outcomes. We target estimation of the marginal distributions of potential…

Methodology · Statistics 2025-11-21 Linda Amoafo , Shiyao Xu , Elizabeth Platz , Daniel Scharfstein

Large Language Models (LLMs) have emerged as powerful tools for passage reranking in information retrieval, leveraging their superior reasoning capabilities to address the limitations of conventional models on complex queries. However,…

Information Retrieval · Computer Science 2026-05-01 Meixiu Long , Duolin Sun , Dan Yang , Yihan Jiao , Lei Liu , Jiahai Wang , BinBin Hu , Yue Shen , Jie Feng , Zhehao Tan , Junjie Wang , Lianzhen Zhong , Jian Wang , Peng Wei , Jinjie Gu

With increasing data availability, causal effects can be evaluated across different data sets, both randomized controlled trials (RCTs) and observational studies. RCTs isolate the effect of the treatment from that of unwanted (confounding)…

We develop inference procedures for longitudinal data where some of the measurements are censored by fixed constants. We consider a semi-parametric quantile regression model that makes no distributional assumptions. Our research is…

Statistics Theory · Mathematics 2009-04-02 Huixia Judy Wang , Mendel Fygenson

Patients with breast cancer tend to die from other diseases, so for studies that focus on breast cancer, a competing risks model is more appropriate. Considering subdistribution hazard ratio, which is used often, limited to model…

Methodology · Statistics 2023-11-21 Zhiyin Yu , Zhaojin Li , Chengfeng Zhang , Yawen Hou , Derun Zhou , Zheng Chen

This article provides a novel approach to assess the importance of specific treatment phases within a treatment regimen through tipping point analyses (TPA) of a time-to-event endpoint using rank-preserving-structural-failure-time (RPSFT)…

Methodology · Statistics 2021-07-06 Sudipta Bhattacharya , Jyotirmoy Dey

Learning-to-rank (LTR) algorithms are ubiquitous and necessary to explore the extensive catalogs of media providers. To avoid the user examining all the results, its preferences are used to provide a subset of relatively small size. The…

Efficiently ranking relevant items from large candidate pools is a cornerstone of modern information retrieval systems -- such as web search, recommendation, and retrieval-augmented generation. Listwise rerankers, which improve relevance by…

Information Retrieval · Computer Science 2025-06-30 Evgeny Dedov

Randomized controlled trials (RCTs) are increasingly prevalent in education research, and are often regarded as a gold standard of causal inference. Two main virtues of randomized experiments are that they (1) do not suffer from…

A central obstacle in the objective assessment of treatment effect (TE) estimators in randomized control trials (RCTs) is the lack of ground truth (or validation set) to test their performance. In this paper, we propose a novel…

We focus on the problem of generalizing a causal effect estimated on a randomized controlled trial (RCT) to a target population described by a set of covariates from observational data. Available methods such as inverse propensity sampling…

Methodology · Statistics 2023-02-27 Imke Mayer , Julie Josse , Traumabase Group
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