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Related papers: Chemical Reaction Networks Learn Better than Spiki…

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How can neural networks such as ResNet efficiently learn CIFAR-10 with test accuracy more than 96%, while other methods, especially kernel methods, fall relatively behind? Can we more provide theoretical justifications for this gap?…

Machine Learning · Computer Science 2020-06-02 Zeyuan Allen-Zhu , Yuanzhi Li

Providing the neurobiological basis of information processing in higher animals, spiking neural networks must be able to learn a variety of complicated computations, including the generation of appropriate, possibly delayed reactions to…

Neurons and Cognition · Quantitative Biology 2016-06-30 Dominik Thalmeier , Marvin Uhlmann , Hilbert J. Kappen , Raoul-Martin Memmesheimer

In real world scenarios, objects are often partially occluded. This requires a robustness for object recognition against these perturbations. Convolutional networks have shown good performances in classification tasks. The learned…

Machine Learning · Computer Science 2019-12-09 René Larisch , Michael Teichmann , Fred H. Hamker

Molecular circuits capable of autonomous learning could unlock novel applications in fields such as bioengineering and synthetic biology. To this end, existing chemical implementations of neural computing have mainly relied on emulating…

Machine Learning · Computer Science 2025-09-23 Rajiv Teja Nagipogu , John H. Reif

Organic reactions are usually assigned to classes containing reactions with similar reagents and mechanisms. Reaction classes facilitate the communication of complex concepts and efficient navigation through chemical reaction space.…

Chemical reactions occur in energy, environmental, biological, and many other natural systems, and the inference of the reaction networks is essential to understand and design the chemical processes in engineering and life sciences. Yet,…

Molecular Networks · Quantitative Biology 2021-01-22 Weiqi Ji , Sili Deng

In machine learning, error back-propagation in multi-layer neural networks (deep learning) has been impressively successful in supervised and reinforcement learning tasks. As a model for learning in the brain, however, deep learning has…

Machine Learning · Computer Science 2016-12-19 Thomas Mesnard , Wulfram Gerstner , Johanni Brea

The rise and fall of artificial neural networks is well documented in the scientific literature of both computer science and computational chemistry. Yet almost two decades later, we are now seeing a resurgence of interest in deep learning,…

Machine Learning · Statistics 2018-08-15 Garrett B. Goh , Nathan O. Hodas , Abhinav Vishnu

Can machine learning algorithms be implemented using chemistry? We demonstrate that this is possible in the case of support vector machines (SVMs). SVMs are powerful tools for data classification, leveraging Vapnik-Chervonenkis theory to…

Molecular Networks · Quantitative Biology 2026-04-02 Amey Choudhary , Jiaxin Jin , Abhishek Deshpande

A recent series of theoretical works showed that the dynamics of neural networks with a certain initialisation are well-captured by kernel methods. Concurrent empirical work demonstrated that kernel methods can come close to the performance…

Machine Learning · Computer Science 2021-06-11 Maria Refinetti , Sebastian Goldt , Florent Krzakala , Lenka Zdeborová

Recent progress in machine learning has sparked increased interest in utilizing this technology to predict the outcomes of chemical reactions. The ultimate aim of such endeavors is to develop a universal model that can predict products for…

Chemical Physics · Physics 2025-07-03 Daniel Julian , Jesús Pérez-Ríos

Hebbian theory seeks to explain how the neurons in the brain adapt to stimuli, to enable learning. An interesting feature of Hebbian learning is that it is an unsupervised method and as such, does not require feedback, making it suitable in…

Neurons and Cognition · Quantitative Biology 2022-06-07 Jakub Fil , Neil Dalchau , Dominique Chu

Chemical reaction networks (CRNs) model the behavior of chemical reactions in well-mixed solutions and they can be designed to perform computations. In this tutorial we give an overview of various computational models for CRNs. Moreover, we…

Emerging Technologies · Computer Science 2018-11-27 Robert Brijder

Reaction virtual screening and discovery are fundamental challenges in chemistry and materials science, where traditional graph neural networks (GNNs) struggle to model multi-reactant interactions. In this work, we propose ChemHGNN, a…

Machine Learning · Computer Science 2025-06-16 Xiaobao Huang , Yihong Ma , Anjali Gurajapu , Jules Schleinitz , Zhichun Guo , Sarah E. Reisman , Nitesh V. Chawla

The automated inference of physically interpretable (bio)chemical reaction network models from measured experimental data is a challenging problem whose solution has significant commercial and academic ramifications. It is demonstrated,…

Neural and Evolutionary Computing · Computer Science 2014-12-22 Dominic P. Searson , Mark J. Willis , Allen Wright

We present a differentiable formulation of abstract chemical reaction networks (CRNs) that can be trained to solve a variety of computational tasks. Chemical reaction networks are one of the most fundamental computational substrates used by…

Molecular Networks · Quantitative Biology 2023-02-07 Alexander Mordvintsev , Ettore Randazzo , Eyvind Niklasson

Chemical reaction networks (CRNs) formally model chemistry in a well-mixed solution. CRNs are widely used to describe information processing occurring in natural cellular regulatory networks, and with upcoming advances in synthetic biology,…

Computational Complexity · Computer Science 2015-03-20 Ho-Lin Chen , David Doty , David Soloveichik

The synergy between spiking neural networks and neuromorphic hardware holds promise for the development of energy-efficient AI applications. Inspired by this potential, we revisit the foundational aspects to study the capabilities of…

Neural and Evolutionary Computing · Computer Science 2024-03-18 Manjot Singh , Adalbert Fono , Gitta Kutyniok

Spiking activity of neurons engaged in learning and performing a task show complex spatiotemporal dynamics. While the output of recurrent network models can learn to perform various tasks, the possible range of recurrent dynamics that…

Neurons and Cognition · Quantitative Biology 2018-08-21 Christopher Kim , Carson Chow

To what extent do the characteristic features of a chemical reaction network reflect its purpose and function? In general, one argues that correlations between specific features and specific functions are key to understanding a complex…

Statistical Mechanics · Physics 2012-03-22 Sang Hoon Lee , Sebastian Bernhardsson , Petter Holme , Beom Jun Kim , Petter Minnhagen
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