English
Related papers

Related papers: ChemFit: A framework for automated high-dimensiona…

200 papers

I present a Python package developed for fitting Voigt profiles to absorption lines. The software fits multiple components for various atomic lines simultaneously allowing parameters to be tied and fixed. Moreover, the code is able to…

Instrumentation and Methods for Astrophysics · Physics 2018-03-06 Jens-Kristian Krogager

The accuracy and efficiency of a coarse-grained (CG) force field are pivotal for high-precision molecular simulations of large systems with complex molecules. We present an automated mapping and optimization framework for molecular…

Computational Physics · Physics 2024-08-14 Zhixuan Zhong , Lifeng Xu , Jian Jiang

In this work, we introduce CHIPS-FF (Computational High-Performance Infrastructure for Predictive Simulation-based Force Fields), a universal, open-source benchmarking platform for machine learning force fields (MLFFs). This platform…

Materials Science · Physics 2025-03-20 Daniel Wines , Kamal Choudhary

Accurate low dimension chemical kinetic models for methane are an essential component in the design of efficient gas turbine combustors. Kinetic models coupled to computational fluid dynamics (CFD) provide quick and efficient ways to test…

Chemical Physics · Physics 2022-06-10 Mark Kelly , Gilles Bourque , Stephen Dooley

We present a software framework for statistical data analysis, called HistFitter, that has been used extensively by the ATLAS Collaboration to analyze big datasets originating from proton-proton collisions at the Large Hadron Collider at…

High Energy Physics - Experiment · Physics 2015-06-23 M. Baak , G. J. Besjes , D. Cote , A. Koutsman , J. Lorenz , D. Short

Random graph models are widely used to understand network properties and graph algorithms. Key to such analyses are the different parameters of each model, which affect various network features, such as its size, clustering, or degree…

Social and Information Networks · Computer Science 2024-02-09 Thomas Bläsius , Sarel Cohen , Philipp Fischbeck , Tobias Friedrich , Martin S. Krejca

Fast and accurate protein structure prediction is one of the major challenges in structural biology, biotechnology and molecular biomedicine. These fields require 3D protein structures for rational design of proteins with improved or novel…

Data Analysis, Statistics and Probability · Physics 2013-11-14 Lars A. Bratholm

We present a collection of tools automating the efficient computation of large sets of theory predictions for high-energy physics. Calculating predictions for different processes often require dedicated programs. These programs, however,…

High Energy Physics - Phenomenology · Physics 2024-01-11 Andrea Barontini , Alessandro Candido , Juan M. Cruz-Martinez , Felix Hekhorn , Christopher Schwan

A large part of modern machine learning theory often involves computing the high-dimensional expected trace of a rational expression of large rectangular random matrices. To symbolically compute such quantities using free probability…

Machine Learning · Computer Science 2025-04-16 Arjun Subramonian , Elvis Dohmatob

The task of estimating a matrix given a sample of observed entries is known as the \emph{matrix completion problem}. Most works on matrix completion have focused on recovering an unknown real-valued low-rank matrix from a random sample of…

Statistics Theory · Mathematics 2014-08-27 Olga Klopp , Jean Lafond , Eric Moulines , Joseph Salmon

Gaussian process (GP) models are commonly used statistical metamodels for emulating expensive computer simulators. Fitting a GP model can be numerically unstable if any pair of design points in the input space are close together. Ranjan,…

Computation · Statistics 2015-11-20 Blake MacDonald , Pritam Ranjan , Hugh Chipman

Semiclassical approximations for quantum dynamic simulations in complex chemical systems range from rigorously accurate methods that are computationally expensive to methods that exhibit near-classical scaling with system size but are…

Chemical Physics · Physics 2022-09-09 Shreyas Malpathak , Matthew S. Church , Nandini Ananth

Inferring parameters of macro-kinetic growth models, typically represented by Ordinary Differential Equations (ODE), from the experimental data is a crucial step in bioprocess engineering. Conventionally, estimates of the parameters are…

Machine Learning · Computer Science 2023-12-07 Maxim Borisyak , Stefan Born , Peter Neubauer , Mariano Nicolas Cruz-Bournazou

Combined-resolution simulations are an effective way to study molecular properties across a range of length- and time-scales. These simulations can benefit from adaptive boundaries that allow the high-resolution region to adapt (change size…

Computational Physics · Physics 2018-05-09 Jason A. Wagoner , Vijay S. Pande

For regulatory and interpretability reasons, logistic regression is still widely used. To improve prediction accuracy and interpretability, a preprocessing step quantizing both continuous and categorical data is usually performed:…

Methodology · Statistics 2019-03-22 Adrien Ehrhardt , Christophe Biernacki , Vincent Vandewalle , Philippe Heinrich

Recent developments in many-body potential energy representation via deep learning have brought new hopes to addressing the accuracy-versus-efficiency dilemma in molecular simulations. Here we describe DeePMD-kit, a package written in…

Computational Physics · Physics 2018-05-23 Han Wang , Linfeng Zhang , Jiequn Han , Weinan E

We present a novel computational paradigm for process design in manufacturing processes that incorporates simulation responses to optimize manufacturing process parameters in high-dimensional temporal and spatial design spaces. We developed…

Computational Engineering, Finance, and Science · Computer Science 2021-07-26 Mojtaba Mozaffar , Jian Cao

We implemented a coarse-graining procedure to construct mesoscopic models of complex molecules. The final aim is to obtain better results on properties depending on slow modes of the molecules. Therefore the number of particles considered…

Soft Condensed Matter · Physics 2009-10-31 Hendrik Meyer , Oliver Biermann , Roland Faller , Dirk Reith , Florian Mueller-Plathe

In applications such as molecule design or drug discovery, it is desirable to have an algorithm which recommends new candidate molecules based on the results of past tests. These molecules first need to be synthesized and then tested for…

Kinetic parameters such as the turnover number ($k_{cat}$) and Michaelis constant ($K_{\mathrm{M}}$) are essential for modelling enzymatic activity but experimental data remains limited in scale and diversity. Previous methods for…

Quantitative Methods · Quantitative Biology 2025-07-22 Saleh Alwer , Ronan Fleming