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The pursuit of human-level artificial intelligence (AI) has significantly advanced the development of autonomous agents and Large Language Models (LLMs). LLMs are now widely utilized as decision-making agents for their ability to interpret…

United States healthcare systems are struggling to meet the growing demand for neurological care, particularly in Alzheimer's disease and related dementias (ADRD). Generative AI built on language models (LLMs) now enables agentic AI systems…

Patient matching is the process of linking patients to appropriate clinical trials by accurately identifying and matching their medical records with trial eligibility criteria. We propose LLM-Match, a novel framework for patient matching…

Computation and Language · Computer Science 2025-03-26 Xiaodi Li , Shaika Chowdhury , Chung Il Wi , Maria Vassilaki , Xiaoke Liu , Terence T Sio , Owen Garrick , Young J Juhn , James R Cerhan , Cui Tao , Nansu Zong

The application of large language models (LLMs) in clinical decision support faces significant challenges of "tunnel vision" and diagnostic hallucinations present in their processing unstructured electronic health records (EHRs). To address…

Artificial Intelligence · Computer Science 2026-04-28 Zhiqi Lv , Duofan Tu , Jun Li , Mingyue Zhao , Heqin Zhu , Wenliang Li , Shaohua Kevin Zhou

Memory emerges as the core module in the large language model (LLM)-based agents for long-horizon complex tasks (e.g., multi-turn dialogue, game playing, scientific discovery), where memory can enable knowledge accumulation, iterative…

Computation and Language · Computer Science 2026-05-04 Yanchen Wu , Tenghui Lin , Yingli Zhou , Fangyuan Zhang , Qintian Guo , Xun Zhou , Sibo Wang , Xilin Liu , Yuchi Ma , Yixiang Fang

Large language model (LLM) systems are increasingly used to support high-stakes decision-making, but they typically perform worse when the available evidence is internally inconsistent. Such a scenario exists in real-world healthcare…

Computation and Language · Computer Science 2026-04-02 Haochen Liu , Weien Li , Rui Song , Zeyu Li , Chun Jason Xue , Xiao-Yang Liu , Sam Nallaperuma , Xue Liu , Ye Yuan

AI agents powered by Large Language Models (LLMs) have made significant advances, enabling them to assist humans in diverse complex tasks and leading to a revolution in human-AI coordination. LLM-powered agents typically require invoking…

Artificial Intelligence · Computer Science 2024-01-10 Jijia Liu , Chao Yu , Jiaxuan Gao , Yuqing Xie , Qingmin Liao , Yi Wu , Yu Wang

Online health resources and large language models (LLMs) are increasingly used as a first point of contact for medical decision-making, yet their reliability in healthcare remains limited by low accuracy, lack of transparency, and…

Artificial Intelligence · Computer Science 2026-04-22 Yujia Liu , Sophia Yu , Hongyue Jin , Jessica Wen , Alexander Qian , Terrence Lee , Mattheus Ramsis , Gi Won Choi , Lianhui Qin , Xin Liu , Edward J. Wang

Game environments provide rich, controllable settings that stimulate many aspects of real-world complexity. As such, game agents offer a valuable testbed for exploring capabilities relevant to Artificial General Intelligence. Recently, the…

Artificial Intelligence · Computer Science 2025-11-05 Sihao Hu , Tiansheng Huang , Gaowen Liu , Ramana Rao Kompella , Fatih Ilhan , Selim Furkan Tekin , Yichang Xu , Zachary Yahn , Ling Liu

Large language models (LLMs) have advanced the field of artificial intelligence (AI) and are a powerful enabler for interactive systems. However, they still face challenges in long-term interactions that require adaptation towards the user…

Artificial Intelligence · Computer Science 2025-05-20 Rebecca Westhäußer , Frederik Berenz , Wolfgang Minker , Sebastian Zepf

Effective pandemic control requires timely and coordinated policymaking across administrative regions that are intrinsically interdependent. However, human-driven responses are often fragmented and reactive, with policies formulated in…

Artificial Intelligence · Computer Science 2026-01-15 Ziyi Shi , Xusen Guo , Hongliang Lu , Mingxing Peng , Haotian Wang , Zheng Zhu , Zhenning Li , Yuxuan Liang , Xinhu Zheng , Hai Yang

Clinical decision-making is a dynamic, interactive, and cyclic process where doctors have to repeatedly decide on which clinical action to perform and consider newly uncovered information for diagnosis and treatment. Large Language Models…

Computation and Language · Computer Science 2026-03-03 David Bani-Harouni , Chantal Pellegrini , Ege Özsoy , Nassir Navab , Matthias Keicher

The integration of deep learning-based glaucoma detection with large language models (LLMs) presents an automated strategy to mitigate ophthalmologist shortages and improve clinical reporting efficiency. However, applying general LLMs to…

Multiagent Systems · Computer Science 2025-12-18 Philip R. Liu , Sparsh Bansal , Jimmy Dinh , Aditya Pawar , Ramani Satishkumar , Shail Desai , Neeraj Gupta , Xin Wang , Shu Hu

The intricate nature of modern surgical care necessitates intelligent systems that can synthesize extensive patient records, support collaborative decision-making, and provide transparent, auditable reasoning across the entire perioperative…

Computation and Language · Computer Science 2026-05-29 Dongsheng Shi , Yue Li , Xin Yi , Yongyi Cui , Huawei Feng , Linlin Wang

Large Language Model (LLM) agents are increasingly used in real-world products, where personalized and context-aware user interactions are essential. A central enabler of such capabilities is the agent's long-term semantic memory system,…

Information Retrieval · Computer Science 2026-05-27 Zhentao Xu , Shangjin Zhang , Emir Poyraz , Yvonne Li , Ye Jin , Xie Lu , Xiaoyang Gu , Karthik Ramgopal , Praveen Kumar Bodigutla , Xiaofeng Wang

The integration of Large Language Models (LLMs) into interactive systems opens new opportunities for adaptive user experiences, yet it also raises challenges regarding accessibility, explainability, and normative compliance. This paper…

Human-Computer Interaction · Computer Science 2026-01-13 Blessing Jerry , Lourdes Moreno , Virginia Francisco , Raquel Hervas

Large Language Model (LLM)-based systems present new opportunities for autonomous health monitoring in sensor-rich industrial environments. This study explores the potential of LLMs to detect and classify faults directly from sensor data,…

Artificial Intelligence · Computer Science 2025-09-30 Xian Yeow Lee , Lasitha Vidyaratne , Ahmed Farahat , Chetan Gupta

Large language models (LLMs) are revolutionizing healthcare by improving diagnosis, patient care, and decision support through interactive communication. More recently, they have been applied to analyzing physiological time-series like…

Computation and Language · Computer Science 2025-04-30 Mohammad Feli , Iman Azimi , Pasi Liljeberg , Amir M. Rahmani

Large Language Model (LLM)-empowered multi-agent systems extend the cognitive boundaries of individual agents through disciplined collaboration and interaction, while constructing these systems often requires labor-intensive manual designs.…

Machine Learning · Computer Science 2025-06-10 Guibin Zhang , Luyang Niu , Junfeng Fang , Kun Wang , Lei Bai , Xiang Wang

The rapid development of large language model (LLM)-based agents has unlocked new possibilities for autonomous multi-turn reasoning and tool-augmented decision-making. However, their real-world deployment is hindered by severe…