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Magnetic Particle Imaging (MPI) is a promising tomographic technique for visualizing the spatio-temporal distribution of superparamagnetic nanoparticles, with applications ranging from cancer detection to real-time cardiovascular…

Computer Vision and Pattern Recognition · Computer Science 2026-01-23 Vladyslav Gapyak , Thomas März , Andreas Weinmann

Magnetic particle imaging (MPI) offers unparalleled contrast and resolution for tracing magnetic nanoparticles. A common imaging procedure calibrates a system matrix (SM) that is used to reconstruct data from subsequent scans. The ill-posed…

Image and Video Processing · Electrical Eng. & Systems 2023-09-07 Alper Güngör , Baris Askin , Damla Alptekin Soydan , Can Barış Top , Emine Ulku Saritas , Tolga Çukur

We contribute to the mathematical modeling and analysis of magnetic particle imaging which is a promising new in-vivo imaging modality. Concerning modeling, we develop a structured decomposition of the imaging process and extract its core…

Numerical Analysis · Mathematics 2016-05-27 Thomas März , Andreas Weinmann

We derive a new 3D model for magnetic particle imaging (MPI) that is able to incorporate realistic magnetic fields in the reconstruction process. In real MPI scanners, the generated magnetic fields have distortions that lead to deformed…

Numerical Analysis · Mathematics 2020-12-30 Gaël Bringout , Wolfgang Erb , Jürgen Frikel

Magnetic Particle Imaging (MPI) is a promising noninvasive in vivo imaging modality that makes it possible to map the spatial distribution of superparamagnetic nanoparticles by exposing them to dynamic magnetic fields. In the Field-Free…

Numerical Analysis · Mathematics 2025-08-08 Vladyslav Gapyak , Thomas März , Andreas Weinmann

Various imaging modalities allow for time-dependent image reconstructions from measurements where its acquisition also has a time-dependent nature. Magnetic particle imaging (MPI) falls into this class of imaging modalities and it thus also…

Numerical Analysis · Mathematics 2023-06-21 Christina Brandt , Tobias Kluth , Tobias Knopp , Lena Westen

Magnetic particle imaging (MPI) is a tracer-based imaging modality that detects superparamagnetic iron oxide nanoparticles in vivo, with applications in cancer cell tracking, lymph node mapping, and cell therapy monitoring. We introduce a…

Objective: This work introduces a new magnetic particle imaging (MPI) reconstruction framework based on multi-harmonic 3D deconvolution (MH3D) of gridded portraits, offering a principled, model-driven approach to MPI imaging. Approach: MH3D…

Numerical Analysis · Mathematics 2025-10-02 Toby Sanders , Justin J. Konkle , Erica E. Mason , Patrick W. Goodwill

The purpose of this study was to present image reconstruction methods for magnetic particle imaging (MPI) with a field-free-line (FFL) encoding scheme and to propose the use of the maximum likelihood-expectation maximization (ML-EM)…

Medical Physics · Physics 2016-06-13 Kenya Murase

We present a new approach for representing and reconstructing multidimensional magnetic resonance imaging (MRI) data. Our method builds on a novel, learned feature-based image representation that disentangles different types of features,…

Image and Video Processing · Electrical Eng. & Systems 2026-01-01 Ruiyang Zhao , Fan Lam

Magnetic Particle Imaging (MPI) is a tomographic imaging modality capable of real-time, high-sensitivity mapping of superparamagnetic iron oxide nanoparticles. Model-based image reconstruction provides an alternative to conventional methods…

Magnetic particle imaging (MPI) is a relatively new imaging modality. The nonlinear magnetization behavior of nanoparticles in an applied magnetic field is employed to reconstruct an image of the concentration of nanoparticles. Finding a…

Applied Physics · Physics 2018-07-04 Tobias Kluth

Magnetic Particle Imaging (MPI) is a novel imaging modality with important applications such as angiography, stem cell tracking, and cancer imaging. Recently, there have been efforts to increase the functionality of MPI via multi-color…

Medical Physics · Physics 2017-05-23 Yavuz Muslu , Mustafa Utkur , Omer Burak Demirel , Emine Ulku Saritas

Magnetic Particle Imaging is an emerging imaging modality through which it is possible to detect tracers containing superparamagnetic nanoparticles. The exposure of the particles to dynamic magnetic fields generates a non-linear response…

Numerical Analysis · Mathematics 2024-06-19 Vladyslav Gapyak , Thomas März , Andreas Weinmann

Magnetic Particle Imaging (MPI) is a recent imaging modality where superparamagnetic nanoparticles are employed as tracers. The reconstruction task is to obtain the spatial particle distribution from a voltage signal induced by the…

Numerical Analysis · Mathematics 2025-08-11 Thomas März , Vladyslav Gapyak , Andreas Weinmann

Magnetic particle imaging (MPI) is an emerging medical imaging modality which offers a unique combination of high temporal and spatial resolution, sensitivity and biocompatibility. For system-matrix (SM) based image reconstruction in MPI, a…

Software Engineering · Computer Science 2024-01-12 Anselm von Gladiss , Amir Shayan Ahmadian , Jan Jürjens

Detail features of magnetic resonance images play a cru-cial role in accurate medical diagnosis and treatment, as they capture subtle changes that pose challenges for doc-tors when performing precise judgments. However, the widely utilized…

Computer Vision and Pattern Recognition · Computer Science 2024-05-10 Mengxiao Geng , Jiahao Zhu , Xiaolin Zhu , Qiqing Liu , Dong Liang , Qiegen Liu

Magnetic particle imaging (MPI) is an imaging modality exploiting the nonlinear magnetization behavior of (super-)paramagnetic nanoparticles to obtain a space- and often also time-dependent concentration of a tracer consisting of these…

Image and Video Processing · Electrical Eng. & Systems 2020-07-06 Sören Dittmer , Tobias Kluth , Mads Thorstein Roar Henriksen , Peter Maass

Purpose: Although recent deep energy-based generative models (EBMs) have shown encouraging results in many image generation tasks, how to take advantage of the self-adversarial cogitation in deep EBMs to boost the performance of Magnetic…

Image and Video Processing · Electrical Eng. & Systems 2021-09-10 Yu Guan , Zongjiang Tu , Shanshan Wang , Qiegen Liu , Yuhao Wang , Dong Liang

Purpose: To develop a general framework for Parallel Imaging (PI) with the use of Maxwell regularization for the estimation of the sensitivity maps (SMs) and constrained optimization for the parameter-free image reconstruction. Theory and…

Image and Video Processing · Electrical Eng. & Systems 2020-08-21 Matteo Alessandro Francavilla , Stamatios Lefkimmiatis , Jorge F. Villena , Athanasios G. Polimeridis
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