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Designing RNA molecules has garnered recent interest in medicine, synthetic biology, biotechnology and bioinformatics since many functional RNA molecules were shown to be involved in regulatory processes for transcription, epigenetics and…

Machine Learning · Computer Science 2019-04-15 Frederic Runge , Danny Stoll , Stefan Falkner , Frank Hutter

Reversible logic has received great attention in the recent years due to their ability to reduce the power dissipation which is the main requirement in low power digital design. It has wide applications advanced computing, low power CMOS…

Other Computer Science · Computer Science 2010-03-25 H. R. Bhagyalakshmi , M. K. Venkatesha

DNA Data storage has recently attracted much attention due to its durable preservation and extremely high information density (bits per gram) properties. In this work, we propose a hybrid coding strategy comprising of generalized…

Information Theory · Computer Science 2021-12-20 Yixin Wang , Li Deng , Md. Noor-A-Rahim , Erry Gunawan , Yong L. Guan , Zhi P. Shi , Chueh L. Poh

We describe properties and constructions of constraint-based codes for DNA-based data storage which account for the maximum repetition length and AT/GC balance. We present algorithms for computing the number of sequences with maximum…

Information Theory · Computer Science 2018-12-18 Kees A. Schouhamer Immink , Kui Cai

In recent years, reversible logic has emerged as a promising computing paradigm having its applications in low power computing, quantum computing, nanotechnology, optical computing and DNA computing. The classical set of gates such as AND,…

Hardware Architecture · Computer Science 2007-05-23 Himanshu Thapliyal , M. B Srinivas

Transformer models have revolutionized AI tasks, but their large size hinders real-world deployment on resource-constrained and latency-critical edge devices. While binarized Transformers offer a promising solution by significantly reducing…

Machine Learning · Computer Science 2025-05-13 Yuhao Ji , Chao Fang , Shaobo Ma , Haikuo Shao , Zhongfeng Wang

Recently, the deep neural network (derived from the artificial neural network) has attracted many researchers' attention by its outstanding performance. However, since this network requires high-performance GPUs and large storage, it is…

Neural and Evolutionary Computing · Computer Science 2016-02-25 Song Wang , Dongchun Ren , Li Chen , Wei Fan , Jun Sun , Satoshi Naoi

In today's world everyday a new technology which is faster, smaller and more complex than its predecessor is being developed. The increased number of transistors packed onto a chip of a conventional system results in increased power…

Hardware Architecture · Computer Science 2013-06-11 Aakash Gupta , Pradeep Singla , Jitendra Gupta , Nitin Maheshwari

The increasing computational demand of Convolutional Neural Networks (CNNs) necessitates energy-efficient acceleration strategies. Compute-in-Memory (CIM) architectures based on Resistive Random Access Memory (RRAM) offer a promising…

Signal Processing · Electrical Eng. & Systems 2025-07-25 José Cubero-Cascante , Rebecca Pelke , Noah Flohr , Arunkumar Vaidyanathan , Rainer Leupers , Jan Moritz Joseph

Over the past years, the ever-growing trend on data storage demand, more specifically for "cold" data (i.e. rarely accessed), has motivated research for alternative systems of data storage. Because of its biochemical characteristics,…

Image and Video Processing · Electrical Eng. & Systems 2023-05-11 Xavier Pic , Eva Gil San Antonio , Melpomeni Dimopoulou , Marc Antonini

The inverse design of RNA three-dimensional (3D) structures is crucial for engineering functional RNAs in synthetic biology and therapeutics. While recent deep learning approaches have advanced this field, they are typically optimized and…

Machine Learning · Computer Science 2026-05-11 Tianmeng Hu , Yongzheng Cui , Biao Luo , Ke Li

Despite their tremendous success and versatility, Deep Neural Networks (DNNs) such as Large Language Models (LLMs) suffer from inference inefficiency and rely on advanced computational infrastructure. To address these challenges and make…

Machine Learning · Computer Science 2025-05-05 Mohsen Dehghankar , Mahdi Erfanian , Abolfazl Asudeh

DNA is a leading candidate as the next archival storage media due to its density, durability and sustainability. To read (and write) data DNA storage exploits technology that has been developed over decades to sequence naturally occurring…

Emerging Technologies · Computer Science 2022-05-12 Jasmine Quah , Omer Sella , Thomas Heinis

The proper design of DNA sequences allows for the formation of well defined supramolecular units with controlled interactions via a consecution of self-assembling processes. Here, we benefit from the controlled DNA self-assembly to…

Soft Condensed Matter · Physics 2018-02-14 Javier Fernandez-Castanon , Francesca Bomboi , Francesco Sciortino

The coverage depth problem in DNA data storage is about computing the expected number of reads needed to recover all encoded strands. Given a generator matrix of a linear code, this quantity equals the expected number of randomly drawn…

Information Theory · Computer Science 2026-03-09 Matteo Bertuzzo , Alberto Ravagnani , Eitan Yaakobi

DNA storage systems face significant challenges, including insertion, deletion, and substitution (IDS) errors. Therefore, designing effective synchronization codes, i.e., codes capable of correcting IDS errors, is essential for DNA storage…

Information Theory · Computer Science 2025-05-23 Javad Haghighat , Tolga M. Duman

DNA methylation (DNAme) is a critical component of the epigenetic regulatory machinery and aberrations in DNAme patterns occur in many diseases, such as cancer. Mapping and understanding DNAme profiles offers considerable promise for…

The synthesis of DNA strands remains the most costly part of the DNA storage system. Thus, to make DNA storage system more practical, the time and materials used in the synthesis process have to be optimized. We consider the most common…

Information Theory · Computer Science 2023-05-15 Johan Chrisnata , Han Mao Kiah , Van Long Phuoc Pham

Using Resistive Random Access Memory (RRAM) crossbars in Computing-in-Memory (CIM) architectures offers a promising solution to overcome the von Neumann bottleneck. Due to non-idealities like cell variability, RRAM crossbars are often…

Applications of Binary Neural Networks (BNNs) are promising for embedded systems with hard constraints on computing power. Contrary to conventional neural networks with the floating-point datatype, BNNs use binarized weights and activations…

Emerging Technologies · Computer Science 2022-11-14 Mahdi Zahedi , Taha Shahroodi , Stephan Wong , Said Hamdioui
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