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Graph based molecular representation learning is essential for accurately predicting molecular properties in drug discovery and materials science; however, it faces significant challenges due to the intricate relationships among molecules…

Computational Engineering, Finance, and Science · Computer Science 2025-05-28 Zhengyang Zhou , Yunrui Li , Pengyu Hong , Hao Xu

Depression is one of the most common mental illness problems, and the symptoms shown by patients are not consistent, making it difficult to diagnose in the process of clinical practice and pathological research. Although researchers hope…

Computers and Society · Computer Science 2024-10-08 Xiaohang Xu , Hao Peng , Lichao Sun , Md Zakirul Alam Bhuiyan , Lianzhong Liu , Lifang He

Depression has been the leading cause of mental-health illness worldwide. Major depressive disorder (MDD), is a common mental health disorder that affects both psychologically as well as physically which could lead to loss of lives. Due to…

Computer Vision and Pattern Recognition · Computer Science 2019-09-05 Anupama Ray , Siddharth Kumar , Rutvik Reddy , Prerana Mukherjee , Ritu Garg

Failure to timely diagnose and effectively treat depression leads to over 280 million people suffering from this psychological disorder worldwide. The information cues of depression can be harvested from diverse heterogeneous resources,…

Computer Vision and Pattern Recognition · Computer Science 2022-08-19 Ping-Cheng Wei , Kunyu Peng , Alina Roitberg , Kailun Yang , Jiaming Zhang , Rainer Stiefelhagen

Molecular property prediction constitutes a cornerstone of drug discovery and materials science, necessitating models capable of disentangling complex structure-property relationships across diverse molecular modalities. Existing approaches…

Machine Learning · Computer Science 2026-03-24 Long Xu , Junping Guo , Jianbo Zhao , Jianbo Lu , Yuzhong Peng

Depression is a major mental health condition that severely impacts the emotional and physical well-being of individuals. The simple nature of data collection from social media platforms has attracted significant interest in properly…

Computer Vision and Pattern Recognition · Computer Science 2025-08-12 Md Rezwanul Haque , Md. Milon Islam , S M Taslim Uddin Raju , Hamdi Altaheri , Lobna Nassar , Fakhri Karray

This paper presents our solution to the Multimodal Personality-aware Depression Detection (MPDD) challenge at ACM MM 2025. We propose a multimodal depression detection model in the Elderly that incorporates personality characteristics. We…

Sound · Computer Science 2025-10-10 Honghong Wang , Jing Deng , Rong Zheng

Mental disorders are among the foremost contributors to the global healthcare challenge. Research indicates that timely diagnosis and intervention are vital in treating various mental disorders. However, the early somatization symptoms of…

Computer Vision and Pattern Recognition · Computer Science 2024-09-05 Yichun Li , Shuanglin Li , Syed Mohsen Naqvi

Accurate representation of multimodal knowledge is crucial for event forecasting in real-world scenarios. However, existing studies have largely focused on static settings, overlooking the dynamic acquisition and fusion of multimodal…

Machine Learning · Computer Science 2026-03-27 Feng Zhao , Kangzheng Liu , Teng Peng , Yu Yang , Guandong Xu

Depression has been a leading cause of mental-health illnesses across the world. While the loss of lives due to unmanaged depression is a subject of attention, so is the lack of diagnostic tests and subjectivity involved. Using behavioural…

Artificial Intelligence · Computer Science 2020-10-07 Shivani Shimpi , Shyam Thombre , Snehal Reddy , Ritik Sharma , Srijan Singh

Depression, a prevalent and serious mental health issue, affects approximately 3.8\% of the global population. Despite the existence of effective treatments, over 75\% of individuals in low- and middle-income countries remain untreated,…

Computation and Language · Computer Science 2024-07-19 Shengjie Li , Yinhao Xiao

Major Depressive Disorder (MDD) is a severe illness that affects millions of people, and it is critical to diagnose this disorder as early as possible. Detecting depression from voice signals can be of great help to physicians and can be…

Audio and Speech Processing · Electrical Eng. & Systems 2022-06-28 Jinhan Wang , Vijay Ravi , Jonathan Flint , Abeer Alwan

This paper proposes an introspective deep metric learning (IDML) framework for uncertainty-aware comparisons of images. Conventional deep metric learning methods focus on learning a discriminative embedding to describe the semantic features…

Computer Vision and Pattern Recognition · Computer Science 2023-09-20 Chengkun Wang , Wenzhao Zheng , Zheng Zhu , Jie Zhou , Jiwen Lu

Multimodal regression aims to predict a continuous target from heterogeneous input sources and typically relies on fusion strategies such as early or late fusion. However, existing methods lack principled tools to disentangle and quantify…

Machine Learning · Computer Science 2025-12-29 Zhaozhao Ma , Shujian Yu

Differential diagnosis of mental disorders remains a fundamental challenge in real-world clinical practice, where multiple conditions often exhibit overlapping symptoms. However, most existing public datasets are developed under…

INTRODUCTION: The pharmacological treatment of Major Depressive Disorder (MDD) relies on a trial-and-error approach. We introduce an artificial intelligence (AI) model aiming to personalize treatment and improve outcomes, which was deployed…

We introduce a Reinforcement Learning Psychotherapy AI Companion that generates topic recommendations for therapists based on patient responses. The system uses Deep Reinforcement Learning (DRL) to generate multi-objective policies for four…

Machine Learning · Computer Science 2023-03-20 Baihan Lin , Guillermo Cecchi , Djallel Bouneffouf

We introduce Iterative Dual Reinforcement Learning (IDRL), a new method that takes an optimal discriminator-weighted imitation view of solving RL. Our method is motivated by a simple experiment in which we find training a discriminator…

Machine Learning · Computer Science 2025-04-21 Haoran Xu , Shuozhe Li , Harshit Sikchi , Scott Niekum , Amy Zhang

Current multispectral object detection methods often retain extraneous background or noise during feature fusion, limiting perceptual performance. To address this, we propose an innovative feature fusion framework based on cross-modal…

Computer Vision and Pattern Recognition · Computer Science 2025-09-16 Jifeng Shen , Haibo Zhan , Xin Zuo , Heng Fan , Xiaohui Yuan , Jun Li , Wankou Yang

Automated depression diagnosis aims to analyze multimodal information from interview videos to predict participants' depression scores. Previous studies often lack clear explanations of how these scores were determined, limiting their…

Artificial Intelligence · Computer Science 2026-03-19 Wei Zhang , Juan Chen , En Zhu , Wenhong Cheng , YunPeng Li , Yanbo J. Wang