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The accurate segmentation of lesions in whole-body PET/CT imaging is es-sential for tumor characterization, treatment planning, and response assess-ment, yet current manual workflows are labor-intensive and prone to inter-observer…

Image and Video Processing · Electrical Eng. & Systems 2025-09-04 Moona Mazher , Steven A Niederer , Abdul Qayyum

Recent advancements in foundation models, typically trained with self-supervised learning on large-scale and diverse datasets, have shown great potential in medical image analysis. However, due to the significant spatial heterogeneity of…

Computer Vision and Pattern Recognition · Computer Science 2024-01-25 Lingxiao Luo , Xuanzhong Chen , Bingda Tang , Xinsheng Chen , Rong Han , Chengpeng Hu , Yujiang Li , Ting Chen

The "pre-training then fine-tuning (FT)" paradigm is widely adopted to boost the model performance of deep learning-based methods for medical volumetric segmentation. However, conventional full FT incurs high computational and memory costs.…

Computer Vision and Pattern Recognition · Computer Science 2024-05-29 Jiachen Shen , Wenxuan Wang , Chen Chen , Jianbo Jiao , Jing Liu , Yan Zhang , Shanshan Song , Jiangyun Li

Cardiac image segmentation is an important step in many cardiac image analysis and modeling tasks such as motion tracking or simulations of cardiac mechanics. While deep learning has greatly advanced segmentation in clinical settings, there…

Objective: Positron Emission Tomography (PET) has been a commonly used imaging modality in broad clinical applications. One of the most important tradeoffs in PET imaging is between image quality and radiation dose: high image quality comes…

Image and Video Processing · Electrical Eng. & Systems 2024-04-18 Shaoyan Pan , Elham Abouei , Junbo Peng , Joshua Qian , Jacob F Wynne , Tonghe Wang , Chih-Wei Chang , Justin Roper , Jonathon A Nye , Hui Mao , Xiaofeng Yang

We present a deep learning segmentation model that can automatically and robustly segment all major anatomical structures in body CT images. In this retrospective study, 1204 CT examinations (from the years 2012, 2016, and 2020) were used…

Whole-body PET/CT scan is an important tool for diagnosing various malignancies (e.g., malignant melanoma, lymphoma, or lung cancer), and accurate segmentation of tumors is a key part for subsequent treatment. In recent years, CNN-based…

Image and Video Processing · Electrical Eng. & Systems 2023-02-27 Hengzhi Xue , Qingqing Fang , Yudong Yao , Yueyang Teng

Synthetic PET images are valuable for quantitative imaging workflow development, scalable virtual imaging trials, and deep learning model training, but conventional physics-based simulation approaches are computationally intensive, limited…

Computer Vision and Pattern Recognition · Computer Science 2026-05-21 Suya Li , Kaushik Dutta , Debojyoti Pal , Jingqin Luo , Kooresh I. Shoghi

Sequential whole-body 18F-Fluorodeoxyglucose (FDG) positron emission tomography (PET) scans are regarded as the imaging modality of choice for the assessment of treatment response in the lymphomas because they detect treatment response when…

Image and Video Processing · Electrical Eng. & Systems 2021-06-10 Kai-Chieh Liang , Lei Bi , Ashnil Kumar , Michael Fulham , Jinman Kim

Medical image segmentation plays a pivotal role in clinical diagnostics and treatment planning, yet existing models often face challenges in generalization and in handling both 2D and 3D data uniformly. In this paper, we introduce Medical…

Computer Vision and Pattern Recognition · Computer Science 2024-12-06 Jiayuan Zhu , Abdullah Hamdi , Yunli Qi , Yueming Jin , Junde Wu

Background: A crucial initial processing step for quantitative PET/CT analysis is the segmentation of tumor lesions enabling accurate feature ex-traction, tumor characterization, oncologic staging, and image-based therapy response…

Image and Video Processing · Electrical Eng. & Systems 2022-10-18 Ludovic Sibille , Xinrui Zhan , Lei Xiang

Brain tumor segmentation presents a formidable challenge in the field of Medical Image Segmentation. While deep-learning models have been useful, human expert segmentation remains the most accurate method. The recently released Segment…

Image and Video Processing · Electrical Eng. & Systems 2023-10-11 Mohammad Peivandi , Jason Zhang , Michael Lu , Dongxiao Zhu , Zhifeng Kou

Medical image segmentation is an important analysis task in clinical practice and research. Deep learning has massively advanced the field, but current approaches are mostly based on models trained for a specific task. Training such models…

Image and Video Processing · Electrical Eng. & Systems 2025-12-18 Anwai Archit , Luca Freckmann , Constantin Pape

Despite the remarkable success of deep learning in medical imaging analysis, medical image segmentation remains challenging due to the scarcity of high-quality labeled images for supervision. Further, the significant domain gap between…

Computer Vision and Pattern Recognition · Computer Science 2024-04-26 Hedda Cohen Indelman , Elay Dahan , Angeles M. Perez-Agosto , Carmit Shiran , Doron Shaked , Nati Daniel

Alzheimer's Disease (AD) is the most common form of dementia and often difficult to diagnose due to the multifactorial etiology of dementia. Recent works on neuroimaging-based computer-aided diagnosis with deep neural networks (DNNs) showed…

Image and Video Processing · Electrical Eng. & Systems 2022-07-06 Marla Narazani , Ignacio Sarasua , Sebastian Pölsterl , Aldana Lizarraga , Igor Yakushev , Christian Wachinger

Tumor segmentation in PET-CT images is challenging due to the dual nature of the acquired information: low metabolic information in CT and low spatial resolution in PET. U-Net architecture is the most common and widely recognized approach…

Image and Video Processing · Electrical Eng. & Systems 2022-10-06 Simone Bendazzoli , Mehdi Astaraki

Recent advances in deep learning have shown that learning robust feature representations is critical for the success of many computer vision tasks, including medical image segmentation. In particular, both transformer and…

Computer Vision and Pattern Recognition · Computer Science 2025-02-03 David Li , Anvar Kurmukov , Mikhail Goncharov , Roman Sokolov , Mikhail Belyaev

Analyzing CT scans, MRIs and X-rays is pivotal in diagnosing and treating diseases. However, detecting and identifying abnormalities from such medical images is a time-intensive process that requires expert analysis and is prone to…

Image and Video Processing · Electrical Eng. & Systems 2025-03-14 Daniel Syomichev , Padmini Gopinath , Guang-Lin Wei , Eric Chang , Ian Gordon , Amanuel Seifu , Rahul Pemmaraju , Neehar Peri , James Purtilo

Polyp segmentation, a critical concern in medical imaging, has prompted numerous proposed methods aimed at enhancing the quality of segmented masks. While current state-of-the-art techniques produce impressive results, the size and…

Computer Vision and Pattern Recognition · Computer Science 2024-06-24 Quoc-Huy Trinh , Hai-Dang Nguyen , Bao-Tram Nguyen Ngoc , Debesh Jha , Ulas Bagci , Minh-Triet Tran

Organ segmentation in Positron Emission Tomography (PET) plays a vital role in cancer quantification. Low-dose PET (LDPET) provides a safer alternative by reducing radiation exposure. However, the inherent noise and blurred boundaries make…

Tissues and Organs · Quantitative Biology 2025-06-30 Zanting Ye , Xiaolong Niu , Xu Han , Xuanbin Wu , Wantong Lu , Yijun Lu , Hao Sun , Yanchao Huang , Hubing Wu , Lijun Lu