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Mobile health studies often collect multiple within-day self-reported assessments of participants' behavior and well-being on different scales such as physical activity (continuous), pain levels (truncated), mood states (ordinal), and life…

Methodology · Statistics 2023-09-22 Debangan Dey , Rahul Ghosal , Kathleen Merikangas , Vadim Zipunnikov

Multivariate functional principal component analysis (MFPCA) is a powerful dimension reduction technique for analyzing multiple functional variables simultaneously. However, existing MFPCA methods assume that all functional observations are…

Classical multivariate principal component analysis has been extended to functional data and termed functional principal component analysis (FPCA). Most existing FPCA approaches do not accommodate covariate information, and it is the goal…

Statistics Theory · Mathematics 2010-03-02 Ci-Ren Jiang , Jane-Ling Wang

Digital health technologies enable high-frequency collection of data in near-continuous time and capture rich information about the health of individuals. The raw data collected by these devices often have a hierarchical functional…

Traditional Functional Principal Component Analysis typically focuses on densely observed univariate functional data, yet many applications, particularly in longitudinal studies, involve multivariate functional data observed sparsely and…

Methodology · Statistics 2026-03-23 Uche Mbaka , Michelle Carey

Analyzing longitudinal data in health studies is challenging due to sparse and error-prone measurements, strong within-individual correlation, missing data and various trajectory shapes. While mixed-effect models (MM) effectively address…

Methodology · Statistics 2024-07-11 Corentin Ségalas , Catherine Helmer , Robin Genuer , Cécile Proust-Lima

We propose generalized conditional functional principal components analysis (GC-FPCA) for the joint modeling of the fixed and random effects of non-Gaussian functional outcomes. The method scales up to very large functional data sets by…

Methodology · Statistics 2024-11-18 Yu Lu , Xinkai Zhou , Erjia Cui , Dustin Rogers , Ciprian M. Crainiceanu , Julia Wrobel , Andrew Leroux

Functional Principal Component Analysis (FPCA) has become a widely-used dimension reduction tool for functional data analysis. When additional covariates are available, existing FPCA models integrate them either in the mean function or in…

Methodology · Statistics 2022-04-13 Ci-Ren Jiang , Eardi Lila , John AD Aston , Jane-Ling Wang

In Structural Health Monitoring (SHM), sensor measurements and derived features such as eigenfrequencies often exhibit systematic daily patterns and can therefore be naturally represented as functional data. Furthermore, these patterns are…

Methodology · Statistics 2026-03-20 Philipp Wittenberg , Lizzie Neumann , Kristof Maes , Jan Gertheiss

We propose a Bayesian modeling framework for jointly analyzing multiple functional responses of different types (e.g. binary and continuous data). Our approach is based on a multivariate latent Gaussian process and models the dependence…

Methodology · Statistics 2016-01-12 Beth A. Tidemann-Miller , Brian J. Reich , Ana-Maria Staicu

This study presents the development of multivariate functional Moran's I, along with a novel approach termed multivariate functional areal spatial principal component analysis (mfasPCA), specifically designed for analyzing functional areal…

With the advance of modern technology, more and more data are being recorded continuously during a time interval or intermittently at several discrete time points. They are both examples of "functional data", which have become a prevailing…

Methodology · Statistics 2015-07-21 Jane-Ling Wang , Jeng-Min Chiou , Hans-Georg Mueller

Functional Principal Components Analysis (FPCA) provides a parsimonious, semi-parametric model for multivariate, sparsely-observed functional data. Frequentist FPCA approaches estimate principal components (PCs) from the data, then…

Methodology · Statistics 2026-05-11 Joseph Sartini , Scott Zeger , Ciprian Crainiceanu

A number of challenges exist for the analysis of mHealth data: maintaining participant engagement over extended time periods and therefore understanding what constitutes an acceptable threshold of missing data; distinguishing between the…

The literature on high-dimensional functional data focuses on either the dependence over time or the correlation among functional variables. In this paper, we propose a factor-guided functional principal component analysis (FaFPCA) method…

Methodology · Statistics 2022-11-23 Shoudao Wen , Huazhen Lin

Between 2011 and 2014 NHANES collected objectively measured physical activity data using wrist-worn accelerometers for tens of thousands of individuals for up to seven days. In this study, we analyze minute-level indicators of being active,…

Methodology · Statistics 2025-04-01 Xinkai Zhou , Julia Wrobel , Ciprian M. Crainiceanu , Andrew Leroux

Functional principal component analysis (FPCA) could become invalid when data involve non-Gaussian features. Therefore, we aim to develop a general FPCA method to adapt to such non-Gaussian cases. A Kenall's $\tau$ function, which possesses…

Methodology · Statistics 2021-08-18 Rou Zhong , Shishi Liu , Haocheng Li , Jingxiao Zhang

The Sleep Heart Health Study (SHHS) is a comprehensive landmark study of sleep and its impacts on health outcomes. A primary metric of the SHHS is the in-home polysomnogram, which includes two electroencephalographic (EEG) channels for each…

Applications · Statistics 2009-06-09 Chong-Zhi Di , Ciprian M. Crainiceanu , Brian S. Caffo , Naresh M. Punjabi

Multilinear Principal Component Analysis (MPCA) is a widely utilized method for the dimension reduction of tensor data. However, the integration of MPCA into federated learning remains unexplored in existing research. To tackle this gap,…

Machine Learning · Computer Science 2024-04-30 Chengyu Zhou , Yuqi Su , Tangbin Xia , Xiaolei Fang

Functional principal component analysis (FPCA) is a key tool in the study of functional data, driving both exploratory analyses and feature construction for use in formal modeling and testing procedures. However, existing methods for FPCA…

Methodology · Statistics 2026-03-24 Caitrin Murphy , Eric Laber , Rhonda Merwin , Brian Reich , Jake Koerner
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