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Diffusion Models have shown remarkable proficiency in image and video synthesis. As model size and latency increase limit user experience, hybrid edge-cloud collaborative framework was recently proposed to realize fast inference and…
While diffusion models have set a new benchmark for quality in Low-Dose Computed Tomography (LDCT) denoising, their clinical adoption is critically hindered by extreme computational costs, with inference times often exceeding thousands of…
Dual-target structure-based drug design aims to generate a single ligand together with two pocket-specific binding poses, each compatible with a corresponding target pocket, enabling polypharmacological therapies with improved efficacy and…
Diffusion models have emerged as a powerful class of generative models across various modalities, including image, video, and audio synthesis. However, their deployment is often limited by significant inference latency, primarily due to the…
Diffusion large language models (dLLMs) offer a promising paradigm for parallel text generation, but in practice they face an accuracy-parallelism trade-off, where increasing tokens per forward (TPF) often degrades generation quality.…
Low-dose computed tomography (LDCT) image reconstruction techniques can reduce patient radiation exposure while maintaining acceptable imaging quality. Deep learning is widely used in this problem, but the performance of testing data…
Low-field to high-field MRI synthesis has emerged as a cost-effective strategy to enhance image quality under hardware and acquisition constraints, particularly in scenarios where access to high-field scanners is limited or impractical.…
Despite recent advancements in deep learning, deep neural networks continue to suffer from performance degradation when applied to new data that differs from training data. Test-time adaptation (TTA) aims to address this challenge by…
This paper presents Diffusion via Autoregressive models (D-AR), a new paradigm recasting the image diffusion process as a vanilla autoregressive procedure in the standard next-token-prediction fashion. We start by designing the tokenizer…
Pixel-space diffusion has recently re-emerged as a strong alternative to latent diffusion, enabling high-quality generation without pretrained autoencoders. However, standard pixel-space diffusion models receive relatively weak semantic…
Diffusion models are powerful, but they require a lot of time and data to train. We propose Patch Diffusion, a generic patch-wise training framework, to significantly reduce the training time costs while improving data efficiency, which…
Recent advances in image generation have made diffusion models powerful tools for creating high-quality images. However, their iterative denoising process makes understanding and interpreting their semantic latent spaces more challenging…
Diffusion models are a class of flexible generative models trained with an approximation to the log-likelihood objective. However, most use cases of diffusion models are not concerned with likelihoods, but instead with downstream objectives…
Predicting the binding structure of a small molecule ligand to a protein -- a task known as molecular docking -- is critical to drug design. Recent deep learning methods that treat docking as a regression problem have decreased runtime…
Camouflaged Object Detection (COD) is a challenging task in computer vision due to the high similarity between camouflaged objects and their surroundings. Existing COD methods primarily employ semantic segmentation, which suffers from…
Training object detectors demands extensive, task-specific annotations, yet this requirement becomes impractical in UAV-based human detection due to constantly shifting target distributions and the scarcity of labeled images. As a remedy,…
Autoregressive(AR)-diffusion hybrid paradigms combine AR's structured modeling with diffusion's photorealistic synthesis, yet suffer from high latency due to sequential AR generation and iterative denoising. In this work, we tackle this…
Coarse-grained (CG) molecular dynamics simulations enable efficient exploration of protein conformational ensembles. However, reconstructing atomic details from CG structures (backmapping) remains a challenging problem. Current approaches…
Prevailing Dataset Distillation (DD) methods leveraging generative models confront two fundamental limitations. First, despite pioneering the use of diffusion models in DD and delivering impressive performance, the vast majority of…
Text-to-image generation via Stable Diffusion models (SDM) have demonstrated remarkable capabilities. However, their computational intensity, particularly in the iterative denoising process, hinders real-time deployment in latency-sensitive…