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In this study we introduce a new technique for symbolic regression that guarantees global optimality. This is achieved by formulating a mixed integer non-linear program (MINLP) whose solution is a symbolic mathematical expression of minimum…

Machine Learning · Statistics 2017-11-16 Vernon Austel , Sanjeeb Dash , Oktay Gunluk , Lior Horesh , Leo Liberti , Giacomo Nannicini , Baruch Schieber

While mixed-integer linear programming and convex programming solvers have advanced significantly over the past several decades, solution technologies for general mixed-integer nonlinear programs (MINLPs) have yet to reach the same level of…

Optimization and Control · Mathematics 2026-04-07 Danial Davarnia , Mohammadreza Kiaghadi , Junyuan Qiu

We present a novel relaxation framework for general mixed-integer nonlinear programming (MINLP) grounded in computational geometry. Our approach constructs polyhedral relaxations by convexifying finite sets of strategically chosen points,…

Optimization and Control · Mathematics 2026-03-20 Haisheng Zhu , Taotao He , Mohit Tawarmalani

This paper presents an efficient Mixed-Integer Nonlinear Programming (MINLP) formulation for systems with discrete control inputs under dwell time constraints. By viewing such systems as a switched system, the problem is decomposed into a…

Optimization and Control · Mathematics 2025-01-10 Ramin Abbasi-Esfeden , Armin Nurkanovic , Moritz Diehl , Panagiotis Patrinos , Jan Swevers

Quadratic programming (QP) is a well-studied fundamental NP-hard optimization problem which optimizes a quadratic objective over a set of linear constraints. In this paper, we reformulate QPs as a mixed-integer linear problem (MILP). This…

Optimization and Control · Mathematics 2018-07-17 Wei Xia , Juan Vera , Luis F. Zuluaga

Global optimization of decision trees is a long-standing challenge in combinatorial optimization, yet such models play an important role in interpretable machine learning. Although the problem has been investigated for several decades, only…

Machine Learning · Computer Science 2026-02-03 Jiancheng Tu , Wenqi Fan , Zhibin Wu

It is well-known that by adding integrality constraints to the semidefinite programming (SDP) relaxation of the max-cut problem, the resulting integer semidefinite program is an exact formulation of the problem. In this paper we show…

Optimization and Control · Mathematics 2023-11-09 Frank de Meijer , Renata Sotirov

This work attempts to combine the strengths of two major technologies that have matured over the last three decades: global mixed-integer nonlinear optimization and branch-and-price. We consider a class of generally nonconvex mixed-integer…

Optimization and Control · Mathematics 2020-01-08 Andrew Allman , Qi Zhang

We present a global optimization approach for solving the maximum a-posteriori (MAP) clustering problem under the Gaussian mixture model.Our approach can accommodate side constraints and it preserves the combinatorial structure of the MAP…

Machine Learning · Statistics 2020-03-18 Patrick Flaherty , Pitchaya Wiratchotisatian , Ji Ah Lee , Zhou Tang , Andrew C. Trapp

We solve large-scale mixed-integer linear programs (MILPs) via distributed asynchronous saddle point computation. This is motivated by the MILPs being able to model problems in multi-agent autonomy, e.g., task assignment problems and…

Optimization and Control · Mathematics 2022-11-23 Luke Fina , Matthew Hale

This paper introduces a novel algorithm for Mixed-Integer Nonlinear Programming (MINLP) problems with multilinear interpolations of look-up tables. These problems arise when objective or constraints contain black-box functions only known at…

Many power systems operation and planning computations (e.g., transmission and generation switching and placement) solve a mixed-integer nonlinear problem (MINLP) with binary variables representing the decision to connect devices to the…

Systems and Control · Electrical Eng. & Systems 2023-04-25 Aayushya Agarwal , Amritanshu Pandey , Larry Pillegi

Our study is motivated by the solution of Mixed-Integer Non-Linear Programming (MINLP) problems with separable non-convex functions via the Sequential Convex MINLP technique, an iterative method whose main characteristic is that of solving,…

Optimization and Control · Mathematics 2022-11-29 Renan Spencer Trindade , Claudia D'Ambrosio , Antonio Frangioni , Claudio Gentile

The floor layout problem (FLP) tasks a designer with positioning a collection of rectangular boxes on a fixed floor in such a way that minimizes total communication costs between the components. While several mixed integer programming (MIP)…

Optimization and Control · Mathematics 2017-04-12 Joey Huchette , Santanu S. Dey , Juan Pablo Vielma

In this paper, we mainly study one class of convex mixed-integer nonlinear programming problems (MINLPs) with non-differentiable data. By dropping the differentiability assumption, we substitute gradients with subgradients obtained from KKT…

Optimization and Control · Mathematics 2015-09-22 Zhou Wei , M. Montaz Ali

We present a new mixed-integer programming (MIP) approach for offline multiple change-point detection by casting the problem as a globally optimal piecewise linear (PWL) fitting problem. Our main contribution is a family of strengthened MIP…

Optimization and Control · Mathematics 2026-02-13 Apoorva Narula , Santanu S. Dey , Yao Xie

Mixed integer nonlinear programs (MINLPs) are arguably among the hardest optimization problems, with a wide range of applications. MINLP solvers that are based on linear relaxations and spatial branching work similar as mixed integer…

Optimization and Control · Mathematics 2019-02-08 Jakob Witzig , Timo Berthold , Stefan Heinz

Facility and covering location models are key elements in many decision aid tools in logistics, supply chain design, telecommunications, public infrastructure planning, and many other industrial and public sectors. In many applications, it…

Optimization and Control · Mathematics 2019-09-12 Eduardo Álvarez-Miranda , Markus Sinnl

This paper considers the generalized maximal covering location problem (GMCLP) which establishes a fixed number of facilities to maximize the weighted sum of the covered customers, allowing customer weights to be positive or negative. Due…

Optimization and Control · Mathematics 2025-05-12 Wei Lv , Cheng-Yang Yu , Jie Liang , Wei-Kun Chen , Yu-Hong Dai

The last milestone achievement for the roundoff-error-free solution of general mixed integer programs over the rational numbers was a hybrid-precision branch-and-bound algorithm published by Cook, Koch, Steffy, and Wolter in 2013. We…

Optimization and Control · Mathematics 2021-01-25 Leon Eifler , Ambros Gleixner