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In recent years, with rapid progress in the development of quantum technologies, quantum machine learning has attracted a lot of interest. In particular, a family of hybrid quantum-classical neural networks, consisting of classical and…

Quantum Physics · Physics 2021-11-01 Yixiong Chen

Current quantum neural networks suffer from extreme sensitivity to both adversarial perturbations and hardware noise, creating a significant barrier to real-world deployment. Existing robustness techniques typically sacrifice clean accuracy…

Quantum Physics · Physics 2026-01-27 Mohamed Afane , Quanjiang Long , Haoting Shen , Ying Mao , Junaid Farooq , Ying Wang , Juntao Chen

Graph-structured data commonly arise in many real-world applications, and this extends naturally into the quantum setting, where quantum data with inherent graph structures are frequently generated by typical quantum data sources. However,…

Quantum Physics · Physics 2025-08-27 Yanying Liang , Sile Tang , Zhehao Yi , Haozhen Situ , Zhu-Jun Zheng

We introduce RinQ, a hybrid quantum-classical framework for identifying functionally critical residues in proteins by formulating centrality detection as a Quadratic Unconstrained Binary Optimization (QUBO) problem. Protein structures are…

Quantum Physics · Physics 2025-09-12 Shah Ishmam Mohtashim

We present an effective application of quantum machine learning in histopathological cancer detection. The study here emphasizes two primary applications of hybrid classical-quantum Deep Learning models. The first application is to build a…

Quantum Physics · Physics 2023-09-13 Biswaraj Baral , Reek Majumdar , Bhavika Bhalgamiya , Taposh Dutta Roy

High-fidelity electron microscopy simulations required for quantitative crystal structure refinements face a fundamental challenge: while physical interactions are well-described theoretically, real-world experimental effects are…

Hybrid variational quantum algorithms are promising for solving practical problems, such as combinatorial optimization, quantum chemistry simulation, quantum machine learning, and quantum error correction on noisy quantum computers.…

This study introduces a hybrid quantum-classical dispatching framework designed for power systems with high renewable penetration. The proposed method integrates a variational quantum algorithm with classical optimization to provide…

Quantum Physics · Physics 2026-01-27 Fu Zhang , Yuming Zhao

This work addresses the challenge of enabling practitioners without quantum expertise to transition from classical to hybrid quantum-classical machine learning workflows. We propose a three-stage framework: starting with a classical…

This study presents a systematic comparison between hybrid quantum-classical neural networks and purely classical models across three benchmark datasets (MNIST, CIFAR100, and STL10) to evaluate their performance, efficiency, and robustness.…

Computer Vision and Pattern Recognition · Computer Science 2025-09-18 Muhammad Adnan Shahzad

We present a hybrid quantum-classical recurrent neural network (QRNN) architecture in which the recurrent core is realized as a parametrized quantum circuit (PQC) controlled by a classical feedforward network. The hidden state is the…

Machine Learning · Computer Science 2025-11-05 Wenduan Xu

The taxonomic composition and abundance of phytoplankton, having direct impact on marine ecosystem dynamic and global environment change, are listed as essential ocean variables. Phytoplankton classification is very crucial for…

Quantum Physics · Physics 2023-03-08 Shangshang Shi , Zhimin Wang , Ruimin Shang , Yanan Li , Jiaxin Li , Guoqiang Zhong , Yongjian Gu

Quantum embedding is a fundamental prerequisite for applying quantum machine learning techniques to classical data, and has substantial impacts on performance outcomes. In this study, we present Neural Quantum Embedding (NQE), a method that…

Quantum Physics · Physics 2024-08-12 Tak Hur , Israel F. Araujo , Daniel K. Park

Quantum circuits embed data in a Hilbert space whose dimensionality grows exponentially with the number of qubits, allowing even shallow parameterised quantum circuits (PQCs) to represent highly-correlated probability distributions that are…

Quantum Physics · Physics 2025-10-03 Jie Luo , Jeremy Kulcsar , Xueyin Chen , Giulio Giaconi , Georgios Korpas

Recently, there has been growing attention on combining quantum machine learning (QML) with classical deep learning approaches, as computational techniques are key to improving the performance of image classification tasks. This study…

Machine Learning · Computer Science 2025-10-29 Md. Farhan Shahriyar , Gazi Tanbhir , Abdullah Md Raihan Chy

Recovery rate prediction plays a pivotal role in bond investment strategies by enhancing risk assessment, optimizing portfolio allocation, improving pricing accuracy, and supporting effective credit risk management. However, accurate…

Computational Finance · Quantitative Finance 2026-01-27 Ying Chen , Paul Griffin , Paolo Recchia , Lei Zhou , Hongrui Zhang

Deep learning is one of the most successful and far-reaching strategies used in machine learning today. However, the scale and utility of neural networks is still greatly limited by the current hardware used to train them. These concerns…

Machine Learning · Computer Science 2022-01-12 Davis Arthur , Prasanna Date

The integration of high-penetration renewable energy introduces significant stochasticity and non-convexity into power system dispatching, challenging the computational limits of classical optimization. While Variational Quantum Algorithms…

Quantum Physics · Physics 2026-01-27 Fu Zhang , Yuming Zhao

Motivation: Drug discovery demands rapid quantification of compound-protein interaction (CPI). However, there is a lack of methods that can predict compound-protein affinity from sequences alone with high applicability, accuracy, and…

Biomolecules · Quantitative Biology 2020-12-17 Mostafa Karimi , Di Wu , Zhangyang Wang , Yang Shen

Over the past decade, machine learning revolutionized vision-based quality assessment for which convolutional neural networks (CNNs) have now become the standard. In this paper, we consider a potential next step in this development and…

Quantum Physics · Physics 2022-06-09 Barry D. Reese , Marek Kowalik , Christian Metzl , Christian Bauckhage , Eldar Sultanow