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Quantum computing offers the potential for superior computational capabilities, particularly for data-intensive tasks. However, the current state of quantum hardware puts heavy restrictions on input size. To address this, hybrid transfer…

Quantum machine learning has emerged as a promising approach for medical image analysis, particularly in settings where compact models and expressive feature representations are desired. This paper presents a hybrid classical--quantum…

Computer Vision and Pattern Recognition · Computer Science 2026-05-01 Shabnam Sodagari , Tommy Long

The integration of quantum machine learning with classical deep learning offers promising avenues for medical image analysis by mapping data into high-dimensional Hilbert spaces. However, effectively unifying these distinct paradigms…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Yasmin Rodrigues Sobrinho , João Renato Ribeiro Manesco , João Paulo Papa

One of the main challenges in drug discovery is to find molecules that bind specifically and strongly to their target protein while having minimal binding to other proteins. By predicting binding affinity, it is possible to identify the…

Quantum Physics · Physics 2023-01-19 L. Domingo , M. Djukic , C. Johnson , F. Borondo

Protein-ligand binding affinity is critical in drug discovery, but experimentally determining it is time-consuming and expensive. Artificial intelligence (AI) has been used to predict binding affinity, significantly accelerating this…

Emerging Technologies · Computer Science 2025-09-16 Seon-Geun Jeong , Kyeong-Hwan Moon , Won-Joo Hwang

Variational quantum circuits are increasingly studied as continuous-function approximators, but quantum regression remains difficult to train when global losses, finite-shot stochasticity, and circuit-depth growth combine to produce weak or…

Machine Learning · Computer Science 2026-05-14 Qingyu Meng , Yangshuai Wang

We introduce a Hybrid Quantum Residual Network (HQRN) and establish an exact functional correspondence between its state evolution and the dynamics of classical networks with residual connections. When inputs are restricted to the…

Quantum Physics · Physics 2026-04-20 Junxu Li

Breast cancer diagnosis through thermographic image analysis remains a critical challenge in medical AI, with classical deep learning approaches facing limitations in complex thermal pattern classification tasks. This paper presents a novel…

Hybrid quantum and classical learning aims to couple quantum feature maps with the robustness of classical neural networks, yet most architectures treat the quantum circuit as an isolated feature extractor and merge its measurements with…

Machine Learning · Computer Science 2025-12-23 Azadeh Alavi , Fatemeh Kouchmeshki , Abdolrahman Alavi

Modern cyberattacks are increasingly complex, posing significant challenges to classical machine learning methods, particularly when labeled data is limited and feature interactions are highly non-linear. In this study we investigates the…

Cryptography and Security · Computer Science 2026-01-06 Jessica A. Sciammarelli , Waqas Ahmed

Deep learning has been shown to be able to recognize data patterns better than humans in specific circumstances or contexts. In parallel, quantum computing has demonstrated to be able to output complex wave functions with a few number of…

Quantum Physics · Physics 2021-08-05 Junhua Liu , Kwan Hui Lim , Kristin L. Wood , Wei Huang , Chu Guo , He-Liang Huang

Hybrid quantum-classical models represent a crucial step toward leveraging near-term quantum devices for sequential data processing. We present Quantum Recurrent Neural Networks (QRNNs) and Quantum Convolutional Neural Networks (QCNNs) as…

Quantum Physics · Physics 2025-12-16 Stefan Balauca , Ada-Astrid Balauca , Adrian Iftene

Hybrid quantum-classical machine learning offers a promising direction for advancing automated quality control in industrial settings. In this study, we investigate two hybrid quantum-classical approaches for classifying defects in…

Computer Vision and Pattern Recognition · Computer Science 2026-04-01 Akshaya Srinivasan , Xiaoyin Cheng , Jianming Yi , Alexander Geng , Desislava Ivanova , Andreas Weinmann , Ali Moghiseh

The development of quantum computers has been the stimulus that enables the realization of Quantum Machine Learning (QML), an area that integrates the calculational framework of quantum mechanics with the adaptive properties of classical…

Computational Engineering, Finance, and Science · Computer Science 2025-09-04 Bhavna Bose , Saurav Verma

In this paper, we propose two hybrid quantum-inspired neural networks with adaptive residual and dense connections respectively for pattern recognition. We explain the frameworks of the symmetrical circuit models in the quantum-inspired…

Machine Learning · Computer Science 2025-06-19 Andi Chen , Hua-Lei Yin , Zeng-Bing Chen , Shengjun Wu

The field of drug discovery hinges on the accurate prediction of binding affinity between prospective drug molecules and target proteins, especially when such proteins directly influence disease progression. However, estimating binding…

Accurate classification of microscopic blood cells is still a critical task in medical image analysis, where subtle variations and limited data can challenge conventional deep learning models. As such, we investigate in this work the…

Computer Vision and Pattern Recognition · Computer Science 2026-05-25 Guilherme Cruz , Nouhaila Innan , Alberto Marchisio , Gabriel Falcao , Muhammad Shafique

Hybrid variational quantum algorithms (VQAs) are promising for solving practical problems such as combinatorial optimization, quantum chemistry simulation, quantum machine learning, and quantum error correction on noisy quantum computers.…

Variational quantum algorithms provide a direct, physics-based approach to protein structure prediction, but their accuracy is limited by the coarse resolution of the energy landscapes generated on current noisy devices. We propose a hybrid…

Emerging Technologies · Computer Science 2025-10-09 Yuqi Zhang , Yuxin Yang , Feixiong Chen , Cheng-Chang Lu , Nima Saeidi , Samuel L. Volchenboum , Junhan Zhao , Siwei Chen , Weiwen Jiang , Qiang Guan

Quantum machine learning is often motivated by the idea that quantum systems can expose useful high-dimensional structure that is difficult to access with classical models. We isolate one central component of this claim: the fixed…

Quantum Physics · Physics 2026-05-26 Toheeb Ogunade , Taofeek Kassim , Etinosa Osaro
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