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Quantifying aleatoric uncertainty in medical image segmentation is critical since it is a reflection of the natural variability observed among expert annotators. A conventional approach is to model the segmentation distribution using the…

Computer Vision and Pattern Recognition · Computer Science 2026-04-08 Phi Van Nguyen , Ngoc Huynh Trinh , Duy Minh Lam Nguyen , Phu Loc Nguyen , Quoc Long Tran

Uncertainty estimation in deep learning has become a leading research field in medical image analysis due to the need for safe utilisation of AI algorithms in clinical practice. Most approaches for uncertainty estimation require sampling…

Image and Video Processing · Electrical Eng. & Systems 2022-04-12 Kaisar Kushibar , Víctor Manuel Campello , Lidia Garrucho Moras , Akis Linardos , Petia Radeva , Karim Lekadir

Generalization is an important attribute of machine learning models, particularly for those that are to be deployed in a medical context, where unreliable predictions can have real world consequences. While the failure of models to…

Computer Vision and Pattern Recognition · Computer Science 2022-12-14 Brennan Nichyporuk , Jillian Cardinell , Justin Szeto , Raghav Mehta , Jean-Pierre R. Falet , Douglas L. Arnold , Sotirios A. Tsaftaris , Tal Arbel

Active learning (AL) has found wide applications in medical image segmentation, aiming to alleviate the annotation workload and enhance performance. Conventional uncertainty-based AL methods, such as entropy and Bayesian, often rely on an…

Computer Vision and Pattern Recognition · Computer Science 2024-01-30 Siteng Ma , Haochang Wu , Aonghus Lawlor , Ruihai Dong

The discovery of patterns that accurately discriminate one class label from another remains a challenging data mining task. Subgroup discovery (SD) is one of the frameworks that enables to elicit such interesting hypotheses from labeled…

Data Structures and Algorithms · Computer Science 2017-12-07 Guillaume Bosc , Jean-François Boulicaut , Chedy Raïssi , Mehdi Kaytoue

Annotated datasets are an essential ingredient to train, evaluate, compare and productionalize supervised machine learning models. It is therefore imperative that annotations are of high quality. For their creation, good quality management…

Machine Learning · Computer Science 2024-05-30 Jan-Christoph Klie , Juan Haladjian , Marc Kirchner , Rahul Nair

Liquid chromatography tandem mass spectrometry (LC-MS/MS) is a critical analytical technique for molecular identification across metabolomics, environmental chemistry, and chemical forensics. A variety of computational methods have emerged…

Quantitative Methods · Quantitative Biology 2026-02-10 Mrunali Manjrekar , Runzhong Wang , Samuel Goldman , Jenna C. Fromer , Connor W. Coley

Chemical structure elucidation is a serious bottleneck in analytical chemistry today. We address the problem of identifying an unknown chemical threat given its mass spectrum and its chemical formula, a task which might take well trained…

Detecting and quantifying products of cellular metabolism using Mass Spectrometry (MS) has already shown great promise in many biological and biomedical applications. The biggest challenge in metabolomics is annotation, where measured…

Machine Learning · Computer Science 2020-10-12 Hao Zhu , Liping Liu , Soha Hassoun

In safety-critical applications like medical diagnosis, certainty associated with a model's prediction is just as important as its accuracy. Consequently, uncertainty estimation and reduction play a crucial role. Uncertainty in predictions…

Image and Video Processing · Electrical Eng. & Systems 2023-09-12 Abhishek Singh Sambyal , Narayanan C. Krishnan , Deepti R. Bathula

Applying Artificial Intelligence (AI) and Machine Learning (ML) in critical contexts, such as medicine, requires the implementation of safety measures to reduce risks of harm in case of prediction errors. Spotting ML failures is of…

Machine learning for molecular property prediction has focused largely on pure compounds, even though many practical applications depend on mixtures with intermolecular interactions. Recent work has expanded the availability of mixture…

Machine Learning · Computer Science 2026-05-29 Roel J. Leenhouts , Nathan K. Morgan , William Green , Jan G. Rittig , Florence H. Vermeire

Automatic medical image segmentation is a fundamental step in computer-aided diagnosis, yet fully supervised approaches demand extensive pixel-level annotations that are costly and time-consuming. To alleviate this burden, we propose a…

Computer Vision and Pattern Recognition · Computer Science 2025-10-20 Lei Shi , Gang Li , Junxing Zhang

Semantic segmentation has been widely investigated in the community, in which the state of the art techniques are based on supervised models. Those models have reported unprecedented performance at the cost of requiring a large set of high…

Computer Vision and Pattern Recognition · Computer Science 2022-01-11 Rihuan Ke , Angelica Aviles-Rivero , Saurabh Pandey , Saikumar Reddy , Carola-Bibiane Schönlieb

\noindent Randomized nomination sampling (RNS) is a rank-based sampling technique which has been shown to be effective in several nonparametric studies involving environmental and ecological applications. In this paper, we investigate…

Methodology · Statistics 2015-12-18 Mohammad Nourmohammadi , Mohammad Jafari Jozani , Brad Johnson

A central question in machine learning is how reliable the predictions of a trained model are. Reliability includes the identification of instances for which a model is likely not to be trusted based on an analysis of the learning system…

Quantum Physics · Physics 2026-01-21 Marie Kempkes , Jakob Spiegelberg , Evert van Nieuwenburg , Vedran Dunjko

Objective: Accurate probability estimates are essential for the safe deployment of medical image segmentation models in clinical decision-making. However, modern deep segmentation networks are often poorly calibrated, a problem exacerbated…

Computer Vision and Pattern Recognition · Computer Science 2026-05-05 Meritxell Riera-Marín , Javier García López , Júlia Rodríguez-Comas , Miguel A. González Ballester , Adrian Galdran

Selective classification allows models to abstain from making predictions (e.g., say "I don't know") when in doubt in order to obtain better effective accuracy. While typical selective models can be effective at producing more accurate…

Machine Learning · Computer Science 2024-06-24 Adam Fisch , Tommi Jaakkola , Regina Barzilay

Semi-supervised (SS) semantic segmentation exploits both labeled and unlabeled images to overcome tedious and costly pixel-level annotation problems. Pseudolabel supervision is one of the core approaches of training networks with both…

Computer Vision and Pattern Recognition · Computer Science 2025-01-06 Rini Smita Thakur , Vinod K. Kurmi

Deep learning has emerged as a promising paradigm to give access to highly accurate predictions of molecular and materials properties. A common short-coming shared by current approaches, however, is that neural networks only give point…

Computational Physics · Physics 2023-05-10 Albert Zhu , Simon Batzner , Albert Musaelian , Boris Kozinsky
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