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Hybrid quantum-high performance computing (Q-HPC) workflows are emerging as a key strategy for running quantum applications at scale in current noisy intermediate-scale quantum (NISQ) devices. These workflows must operate seamlessly across…

This work addresses the challenge of enabling practitioners without quantum expertise to transition from classical to hybrid quantum-classical machine learning workflows. We propose a three-stage framework: starting with a classical…

As quantum devices scale toward practical machine learning applications, the binary qubit paradigm faces expressivity and resource efficiency limitations. Multi-level quantum systems, or qudits, offer a promising alternative by harnessing a…

Quantum Physics · Physics 2025-05-09 Tiago de Souza Farias , Lucas Friedrich , Jonas Maziero

Quantum computers are the next evolution of computing hardware. Quantum devices are being exposed through the same familiar cloud platforms used for classical computers, and enabling seamless execution of hybrid applications that combine…

To address the growing needs for scalable High Performance Computing (HPC) and Quantum Computing (QC) integration, we present our HPC-QC full stack framework and its hybrid workload development capability with modular…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-10-24 Xin Zhan , K. Grace Johnson , Aniello Esposito , Barbara Chapman , Marco Fiorentino , Kirk M. Bresniker , Raymond G. Beausoleil , Masoud Mohseni

The development of quantum computers needs reliable quantum hardware and tailored software for controlling electronics specific to various quantum platforms. Middleware is a type of computer software program that aims to provide…

Hybrid quantum systems seek to combine the strength of its constituents to master the fundamental conflicting requirements of quantum technology: fast and accurate systems control together with perfect shielding from the environment,…

Machine learning has been presented as one of the key applications for near-term quantum technologies, given its high commercial value and wide range of applicability. In this work, we introduce the \textit{quantum-assisted Helmholtz…

Quantum Physics · Physics 2018-05-24 Marcello Benedetti , John Realpe-Gómez , Alejandro Perdomo-Ortiz

Quantum computing hardware is affected by quantum noise that undermine the quality of results of an executed quantum program. Amongst other quantum noises, coherent error that caused by parameter drifting and miscalibration, remains…

Hardware Architecture · Computer Science 2024-10-15 Xiangyu Ren , Junjie Wan , Zhiding Liang , Antonio Barbalace

We present a quantum compiler framework that bridges the gap between physics modeling and quantum software development. At the core of this framework is a versatile quantum circuit synthesizer capable of decomposing arbitrary Hamiltonians…

Quantum Physics · Physics 2025-09-25 Shoupu Wan

Solid state superconducting devices coupled to coplanar transmission lines offer an exquisite architecture for quantum optical phenomena probing as well as for quantum computation implementation, being the object of intense theoretical and…

Quantum Physics · Physics 2014-06-09 O. P. de Sa Neto , M. C. de Oliveira

The spin states of single electrons in gate-defined quantum dots satisfy crucial requirements for a practical quantum computer. These include extremely long coherence times, high-fidelity quantum operation, and the ability to shuttle…

Deep neural networks remain highly vulnerable to adversarial perturbations, limiting their reliability in security- and safety-critical applications. To address this challenge, we introduce QShield, a modular hybrid quantum-classical neural…

Cryptography and Security · Computer Science 2026-04-14 Navid Azimi , Aditya Prakash , Yao Wang , Li Xiong

Shortening quantum circuits is crucial to reducing the destructive effect of environmental decoherence and enabling useful algorithms. Here, we demonstrate an improvement in such compilation tasks via a combination of using hybrid…

Quantum machine learning (QML) is promising for potential speedups and improvements in conventional machine learning (ML) tasks (e.g., classification/regression). The search for ideal QML models is an active research field. This includes…

Quantum Physics · Physics 2022-02-07 Mahabubul Alam , Swaroop Ghosh

Contemporary quantum computers are inherently noisy, posing significant challenges for the development and testing of quantum software. Simplified or outdated noise assumptions can lead to incorrect assessments of program correctness,…

Quantum computing based on Neutral Atoms (NAs) provides a wide range of computational capabilities, encompassing high-fidelity long-range interactions with native multi-qubit gates, and the ability to shuttle arrays of qubits. While…

Quantum Physics · Physics 2023-11-27 Ludwig Schmid , Sunghye Park , Seokhyeong Kang , Robert Wille

The exploration of hybrid quantum-classical algorithms and programming models on noisy near-term quantum hardware has begun. As hybrid programs scale towards classical intractability, validation and benchmarking are critical to…

Quantum Physics · Physics 2019-03-06 Alexander McCaskey , Eugene Dumitrescu , Mengsu Chen , Dmitry Lyakh , Travis S. Humble

This paper presents a tool that simplifies quantum software development by unifying circuit design, code generation, and execution within a single cross-platform environment that supports iterative development. Implemented as open source,…

This work describes the theoretical foundation for all quantum chemistry functionality in PennyLane, a quantum computing software library specializing in quantum differentiable programming. We provide an overview of fundamental concepts in…