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Model merging has emerged as a promising solution to accommodate multiple large models within constrained memory budgets. We present StatsMerging, a novel lightweight learning-based model merging method guided by weight distribution…

Machine Learning · Computer Science 2025-06-06 Ranjith Merugu , Bryan Bo Cao , Shubham Jain

While machine learning is currently transforming the field of histopathology, the domain lacks a comprehensive evaluation of state-of-the-art models based on essential but complementary quality requirements beyond a mere classification…

Image and Video Processing · Electrical Eng. & Systems 2023-05-11 Maximilian Springenberg , Annika Frommholz , Markus Wenzel , Eva Weicken , Jackie Ma , Nils Strodthoff

In recent years, deep learning has successfully been applied to automate a wide variety of tasks in diagnostic histopathology. However, fast and reliable localization of small-scale regions-of-interest (ROI) has remained a key challenge, as…

Image and Video Processing · Electrical Eng. & Systems 2022-01-06 Jon Braatz , Pranav Rajpurkar , Stephanie Zhang , Andrew Y. Ng , Jeanne Shen

Large medical imaging datasets can be cheaply and quickly annotated with low-confidence, weak labels (e.g., radiological scores). Access to high-confidence labels, such as histology-based diagnoses, is rare and costly. Pretraining…

Computer Vision and Pattern Recognition · Computer Science 2023-09-20 Emma Sarfati , Alexandre Bône , Marc-Michel Rohé , Pietro Gori , Isabelle Bloch

Assessing microsatellite stability status of a patient's colorectal cancer is crucial in personalizing treatment regime. Recently, convolutional-neural-networks (CNN) combined with transfer-learning approaches were proposed to circumvent…

Computer Vision and Pattern Recognition · Computer Science 2022-08-23 Daniel Shats , Hadar Hezi , Guy Shani , Yosef E. Maruvka , Moti Freiman

Self-supervised pre-training has become the priory choice to establish reliable neural networks for automated recognition of massive biomedical microscopy images, which are routinely annotation-free, without semantics, and without guarantee…

Computer Vision and Pattern Recognition · Computer Science 2023-01-13 Wei Chen , Chen Li , Dan Chen , Xin Luo

Breast cancer is one of the leading causes of death for women worldwide. Early screening is essential for early identification, but the chance of survival declines as the cancer progresses into advanced stages. For this study, the most…

Computer Vision and Pattern Recognition · Computer Science 2023-11-27 Fahad Ahmed , Reem Abdel-Salam , Leon Hamnett , Mary Adewunmi , Temitope Ayano

Pathology is essential for cancer diagnosis, with multiple instance learning (MIL) widely used for whole slide image (WSI) analysis. WSIs exhibit a natural hierarchy -- patches, regions, and slides -- with distinct semantic associations.…

Computer Vision and Pattern Recognition · Computer Science 2025-07-01 Peixiang Huang , Yanyan Huang , Weiqin Zhao , Junjun He , Lequan Yu

Deep learning models that are trained on histopathological images obtained from a single lab and/or scanner give poor inference performance on images obtained from another scanner/lab with a different staining protocol. In recent years,…

Image and Video Processing · Electrical Eng. & Systems 2020-10-07 Harshal Nishar , Nikhil Chavanke , Nitin Singhal

Multiple instance (MI) learning with a convolutional neural network enables end-to-end training in the presence of weak image-level labels. We propose a new method for aggregating predictions from smaller regions of the image into an…

Computer Vision and Pattern Recognition · Computer Science 2018-06-14 Heather D. Couture , J. S. Marron , Charles M. Perou , Melissa A. Troester , Marc Niethammer

The task of parsing subcutaneous vessels in clinical images is often hindered by the high cost and limited availability of ground truth data, as well as the challenge of low contrast and noisy vessel appearances across different patients…

Computer Vision and Pattern Recognition · Computer Science 2026-05-11 Ayaan Nooruddin Siddiqui , Mahnoor Zaidi , Ayesha Nazneen Shahbaz , Priyadarshini Chatterjee , Krishnan Menon Iyer

Virtual stain transfer leverages computer-assisted technology to transform the histochemical staining patterns of tissue samples into other staining types. However, existing methods often lose detailed pathological information due to the…

Computer Vision and Pattern Recognition · Computer Science 2026-04-07 Haiyan Wei , Hangrui Xu , Bingxu Zhu , Yulian Geng , Aolei Liu , Wenfei Yin , Jian Liu

Deep Learning (DL) can predict biomarkers directly from digitized cancer histology in a weakly-supervised setting. Recently, the prediction of continuous biomarkers through regression-based DL has seen an increasing interest. Nonetheless,…

Image and Video Processing · Electrical Eng. & Systems 2024-03-07 Omar S. M. El Nahhas , Georg Wölflein , Marta Ligero , Tim Lenz , Marko van Treeck , Firas Khader , Daniel Truhn , Jakob Nikolas Kather

Whole slide image (WSI) classification is a crucial problem for cancer diagnostics in clinics and hospitals. A WSI, acquired at gigapixel size, is commonly tiled into patches and processed by multiple-instance learning (MIL) models.…

Computer Vision and Pattern Recognition · Computer Science 2024-10-10 Doanh C. Bui , Jin Tae Kwak

Most of the current state-of-the-art methods for tumor segmentation are based on machine learning models trained on manually segmented images. This type of training data is particularly costly, as manual delineation of tumors is not only…

Computer Vision and Pattern Recognition · Computer Science 2019-08-21 Pawel Mlynarski , Hervé Delingette , Antonio Criminisi , Nicholas Ayache

In this paper, we study weakly-supervised laparoscopic image segmentation with sparse annotations. We introduce a novel Bayesian deep learning approach designed to enhance both the accuracy and interpretability of the model's segmentation,…

Computer Vision and Pattern Recognition · Computer Science 2024-10-14 Zhou Zheng , Yuichiro Hayashi , Masahiro Oda , Takayuki Kitasaka , Kensaku Mori

Deep learning and knowledge transfer techniques have permeated the field of medical imaging and are considered as key approaches for revolutionizing diagnostic imaging practices. However, there are still challenges for the successful…

Image and Video Processing · Electrical Eng. & Systems 2020-09-21 Sina Akbarian , Laleh Seyyed-Kalantari , Farzad Khalvati , Elham Dolatabadi

Cancer disease is one of the leading causes of death all over the world. Breast cancer, which is a common cancer disease especially in women, is quite common. The most important tool used for early detection of this cancer type, which…

Image and Video Processing · Electrical Eng. & Systems 2020-12-11 Ali Narin

This paper presents a new supervised classification algorithm for remotely sensed hyperspectral image (HSI) which integrates spectral and spatial information in a unified Bayesian framework. First, we formulate the HSI classification…

Computer Vision and Pattern Recognition · Computer Science 2018-03-14 Xiangyong Cao , Feng Zhou , Lin Xu , Deyu Meng , Zongben Xu , John Paisley

It has been proven that transfer learning provides an easy way to achieve state-of-the-art accuracies on several vision tasks by training a simple classifier on top of features obtained from pre-trained neural networks. The goal of this…

Machine Learning · Computer Science 2016-06-07 Milad Mohammadi , Subhasis Das