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Hematoxylin- and eosin (H&E) stained whole-slide images (WSIs) are the foundation of diagnosis of cancer. In recent years, development of deep learning-based methods in computational pathology enabled the prediction of biomarkers directly…

Transfer Learning enables Convolutional Neural Networks (CNN) to acquire knowledge from a source domain and transfer it to a target domain, where collecting large-scale annotated examples is time-consuming and expensive. Conventionally,…

Computer Vision and Pattern Recognition · Computer Science 2024-01-25 S. H. Shabbeer Basha , Debapriya Tula , Sravan Kumar Vinakota , Shiv Ram Dubey

Though adversarial erasing has prevailed in weakly supervised semantic segmentation to help activate integral object regions, existing approaches still suffer from the dilemma of under-activation and over-expansion due to the difficulty in…

Computer Vision and Pattern Recognition · Computer Science 2024-07-04 Tao Chen , XiRuo Jiang , Gensheng Pei , Zeren Sun , Yucheng Wang , Yazhou Yao

Developing self-supervised learning (SSL) models that can learn universal and transferable representations of H&E gigapixel whole-slide images (WSIs) is becoming increasingly valuable in computational pathology. These models hold the…

Image and Video Processing · Electrical Eng. & Systems 2024-08-07 Guillaume Jaume , Anurag Vaidya , Andrew Zhang , Andrew H. Song , Richard J. Chen , Sharifa Sahai , Dandan Mo , Emilio Madrigal , Long Phi Le , Faisal Mahmood

To address the issues of limited samples, time-consuming feature design, and low accuracy in detection and classification of breast cancer pathological images, a breast cancer image classification model algorithm combining deep learning and…

Image and Video Processing · Electrical Eng. & Systems 2024-09-12 Weimin Wang , Yufeng Li , Xu Yan , Mingxuan Xiao , Min Gao

Early cancer detection is crucial for prognosis, but many cancer types lack large labelled datasets required for developing deep learning models. This paper investigates self-supervised learning (SSL) as an alternative to the standard…

Image and Video Processing · Electrical Eng. & Systems 2024-11-27 Hamish Haggerty , Rohitash Chandra

Cancer pathological analysis requires modeling tumor heterogeneity across multiple modalities, primarily through transcriptomics and whole slide imaging (WSI), along with their spatial relations. On one hand, bulk transcriptomics and WSI…

Machine Learning · Computer Science 2026-03-17 Jingkun Yu , Guangkai Shang , Changtao Li , Xun Gong , Tianrui Li , Yazhou He , Zhipeng Luo

Sparse neural networks are important for achieving better generalization and enhancing computation efficiency. This paper proposes a novel learning approach to obtain sparse fully connected layers in neural networks (NNs) automatically. We…

Machine Learning · Computer Science 2021-04-28 Mengqiao Han , Xiabi Liu , Zhaoyang Hai , Zhengwen Li

Convolutional Neural Networks (CNNs) are the predominant model used for a variety of medical image analysis tasks. At inference time, these models are computationally intensive, especially with volumetric data. In principle, it is possible…

Computer Vision and Pattern Recognition · Computer Science 2023-06-30 Jose Javier Gonzalez Ortiz , John Guttag , Adrian Dalca

Transfer learning has become a standard practice to mitigate the lack of labeled data in medical classification tasks. Whereas finetuning a downstream task using supervised ImageNet pretrained features is straightforward and extensively…

Computer Vision and Pattern Recognition · Computer Science 2023-11-27 Tuan Truong , Sadegh Mohammadi , Matthias Lenga

Multiple instance learning (MIL) has been successfully applied for whole slide images (WSIs) analysis in computational pathology, enabling a wide range of prediction tasks from tumor subtyping to inferring genetic mutations and multi-omics…

Computer Vision and Pattern Recognition · Computer Science 2024-07-25 Junyu Li , Ye Zhang , Wen Shu , Xiaobing Feng , Yingchun Wang , Pengju Yan , Xiaolin Li , Chulin Sha , Min He

Weight-sharing supernets are crucial for performance estimation in cutting-edge neural architecture search (NAS) frameworks. Despite their ability to generate diverse subnetworks without retraining, the quality of these subnetworks is not…

Foundation models (FMs) are transforming computational pathology by offering new ways to analyze histopathology images. However, FMs typically require weeks of training on large databases, making their creation a resource-intensive process.…

Image and Video Processing · Electrical Eng. & Systems 2026-01-27 Till Nicke , Daniela Schacherer , Jan Raphael Schäfer , Natalia Artysh , Antje Prasse , André Homeyer , Andrea Schenk , Henning Höfener , Johannes Lotz

Whole Slide Images (WSIs) in digital pathology are used to diagnose cancer subtypes. The difference in procedures to acquire WSIs at various trial sites gives rise to variability in the histopathology images, thus making consistent…

Image and Video Processing · Electrical Eng. & Systems 2022-04-07 Milad Sikaroudi , Shahryar Rahnamayan , H. R. Tizhoosh

Mutual learning, in which multiple networks learn by sharing their knowledge, improves the performance of each network. However, the performance of ensembles of networks that have undergone mutual learning does not improve significantly…

Computer Vision and Pattern Recognition · Computer Science 2021-03-30 Naoki Okamoto , Soma Minami , Tsubasa Hirakawa , Takayoshi Yamashita , Hironobu Fujiyoshi

Tissue phenotyping is a fundamental task in learning objective characterizations of histopathologic biomarkers within the tumor-immune microenvironment in cancer pathology. However, whole-slide imaging (WSI) is a complex computer vision in…

Computer Vision and Pattern Recognition · Computer Science 2022-03-02 Richard J. Chen , Rahul G. Krishnan

Due to the large size and lack of fine-grained annotation, Whole Slide Images (WSIs) analysis is commonly approached as a Multiple Instance Learning (MIL) problem. However, previous studies only learn from training data, posing a stark…

Computer Vision and Pattern Recognition · Computer Science 2024-11-28 Weiqin Zhao , Ziyu Guo , Yinshuang Fan , Yuming Jiang , Maximus Yeung , Lequan Yu

For ultra-wideband and high-rate wireless communication systems, wideband spectrum sensing (WSS) is critical, since it empowers secondary users (SUs) to capture the spectrum holes for opportunistic transmission. However, WSS encounters…

Information Retrieval · Computer Science 2024-09-16 Jibin Jia , Peihao Dong , Fuhui Zhou , Qihui Wu

In this study, we proposed a deep Swin-Vision Transformer-based transfer learning architecture for robust multi-cancer histopathological image classification. The proposed framework integrates a hierarchical Swin Transformer with…

Image and Video Processing · Electrical Eng. & Systems 2026-04-13 Muazzem Hussain Khan , Tasdid Hasnain , Md. Jamil khan , Ruhul Amin , Md. Shamim Reza , Md. Al Mehedi Hasan , Md Ashad Alam

Precise breast cancer classification on histopathological images has the potential to greatly improve the diagnosis and patient outcome in oncology. The data imbalance problem largely stems from the inherent imbalance within medical image…

Image and Video Processing · Electrical Eng. & Systems 2024-11-28 Majid Behzadpour , Bengie L. Ortiz , Ebrahim Azizi , Kai Wu