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The predict-then-optimize (PTO) framework is a standard approach in data-driven decision-making, where a decision-maker first estimates an unknown parameter from historical data and then uses this estimate to solve an optimization problem.…

Optimization and Control · Mathematics 2025-07-29 Michael Albert , Max Biggs , Ningyuan Chen , Guan Wang

Test-time policy optimization enables large language models (LLMs) to adapt to distribution shifts by leveraging feedback from self-generated rollouts. However, existing methods rely on fixed-budget majority voting to estimate rewards,…

Machine Learning · Computer Science 2025-12-03 Youkang Wang , Jian Wang , Rubing Chen , Tianyi Zeng , Xiao-Yong Wei , Qing Li

The predict-then-optimize (PTO) framework is indispensable for addressing practical stochastic decision-making tasks. It consists of two crucial steps: initially predicting unknown parameters of an optimization model and subsequently…

Systems and Control · Electrical Eng. & Systems 2024-11-20 Jixian Liu , Tao Xu , Jianping He , Chongrong Fang

Predictive models for clinical outcomes that are accurate on average in a patient population may underperform drastically for some subpopulations, potentially introducing or reinforcing inequities in care access and quality. Model training…

Machine Learning · Statistics 2022-02-03 Stephen R. Pfohl , Haoran Zhang , Yizhe Xu , Agata Foryciarz , Marzyeh Ghassemi , Nigam H. Shah

Plateaus, where an agent's performance stagnates at a suboptimal level, are a common problem in deep on-policy RL. Focusing on PPO due to its widespread adoption, we show that plateaus in certain regimes arise not because of known…

Machine Learning · Computer Science 2026-03-09 Michael Beukman , Khimya Khetarpal , Zeyu Zheng , Will Dabney , Jakob Foerster , Michael Dennis , Clare Lyle

In practical applications, data is used to make decisions in two steps: estimation and optimization. First, a machine learning model estimates parameters for a structural model relating decisions to outcomes. Second, a decision is chosen to…

Optimization and Control · Mathematics 2022-10-28 Samuel Tan , Peter I. Frazier

Machine learning applications frequently come with multiple diverse objectives and constraints that can change over time. Accordingly, trained models can be tuned with sets of hyper-parameters that affect their predictive behavior (e.g.,…

Machine Learning · Computer Science 2022-10-17 Bracha Laufer-Goldshtein , Adam Fisch , Regina Barzilay , Tommi Jaakkola

Improvements in return forecast accuracy do not always lead to proportional improvements in portfolio decision quality, especially under realistic trading frictions and constraints. This paper adopts the Smart Predict--then--Optimize (SPO)…

Portfolio Management · Quantitative Finance 2026-01-13 Wang Yi , Takashi Hasuike

Randomized controlled experiments assess new policy impacts on performance metrics to inform launch decisions. Traditional approaches evaluate metrics independently despite correlations, and mixed results (e.g., positive revenue impact,…

Applications · Statistics 2026-01-29 Hoiyi Ng , Guido Imbens

To increase statistical efficiency in a randomized experiment, researchers often use stratification (i.e., blocking) in the design stage. However, conventional practices of stratification fail to exploit valuable information about the…

Methodology · Statistics 2025-10-28 Zikai Li

Modern stochastic optimization pipelines increasingly rely on learned generative models to represent uncertainty, while downstream decisions are evaluated almost entirely through Monte Carlo scenarios. This shifts the operational object of…

Optimization and Control · Mathematics 2026-05-01 Ziwei Zhang , Jonathan Yu-Meng Li

Adjustable hyperparameters of machine learning models typically impact various key trade-offs such as accuracy, fairness, robustness, or inference cost. Our goal in this paper is to find a configuration that adheres to user-specified limits…

Machine Learning · Computer Science 2023-12-05 Bracha Laufer-Goldshtein , Adam Fisch , Regina Barzilay , Tommi Jaakkola

We propose Process-Aware Policy Optimization (PAPO), a method that integrates process-level evaluation into Group Relative Policy Optimization (GRPO) through decoupled advantage normalization, to address two limitations of existing reward…

Artificial Intelligence · Computer Science 2026-04-06 Zelin Tan , Zhouliang Yu , Bohan Lin , Zijie Geng , Hejia Geng , Yudong Zhang , Mulei Zhang , Yang Chen , Shuyue Hu , Zhenfei Yin , Chen Zhang , Lei Bai

Traditionally, optimization of radiation therapy (RT) treatment plans has been done before the initiation of RT course, using population-wide estimates for patients' response to therapy. However, recent technological advancements have…

Medical Physics · Physics 2021-02-15 Stefan C. M. ten Eikelder , Ali Ajdari , Thomas Bortfeld , Dick den Hertog

Adaptive robust optimization (ARO) extends static robust optimization by allowing decisions to depend on the realized uncertainty - weakly dominating static solutions within the modeled uncertainty set. However, ARO makes previous…

Optimization and Control · Mathematics 2025-11-20 Karl Zhu , Dimitris Bertsimas

Reinforcement learning (RL) is the dominant paradigm for post-training large language models. However, in the online, on-policy setting, rollout generation dominates the computational cost of training. Group-based policy optimization…

Machine Learning · Computer Science 2026-05-27 Woojeong Kim , Ziyi Yang , Jing Nathan Yan , Jialu Liu

Recently, preference optimization methods such as DPO have significantly enhanced large language models (LLMs) in wide tasks including dialogue and question-answering. However, current methods fail to account for the varying difficulty…

Computation and Language · Computer Science 2024-12-31 Jingyuan Ma , Rui Li , Zheng Li , Lei Sha , Zhifang Sui

Policy search can in principle acquire complex strategies for control of robots and other autonomous systems. When the policy is trained to process raw sensory inputs, such as images and depth maps, it can also acquire a strategy that…

Machine Learning · Computer Science 2017-02-28 Gregory Kahn , Tianhao Zhang , Sergey Levine , Pieter Abbeel

Traditional RL algorithms like Proximal Policy Optimization (PPO) typically train on the entire rollout buffer, operating under the assumption that all generated episodes provide a beneficial optimization signal. However, these episodes…

Machine Learning · Computer Science 2026-04-03 Dong Shu , Denghui Zhang , Jessica Hullman

Direct Preference Optimization (DPO) has become a popular method for fine-tuning large language models (LLMs) due to its stability and simplicity. However, it is also known to be sensitive to noise in the data and prone to overfitting.…

Machine Learning · Computer Science 2025-10-28 Cheol Woo Kim , Shresth Verma , Mauricio Tec , Milind Tambe
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